ID A0A3Q3BQQ2_HAPBU Unreviewed; 560 AA.
AC A0A3Q3BQQ2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Tensin 3 {ECO:0008006|Google:ProtNLM};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000004191.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000004191.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PTEN phosphatase protein family.
CC {ECO:0000256|ARBA:ARBA00007881}.
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DR AlphaFoldDB; A0A3Q3BQQ2; -.
DR STRING; 8153.ENSHBUP00000004191; -.
DR Ensembl; ENSHBUT00000009118.1; ENSHBUP00000004191.1; ENSHBUG00000005521.1.
DR GeneTree; ENSGT00940000156328; -.
DR OMA; YSISHRE; -.
DR Proteomes; UP000264840; Unplaced.
DR Gene3D; 2.60.40.1110; -; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR014020; Tensin_C2-dom.
DR InterPro; IPR029023; Tensin_phosphatase.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR PANTHER; PTHR45734; TENSIN; 1.
DR PANTHER; PTHR45734:SF5; TENSIN-3; 1.
DR Pfam; PF10409; PTEN_C2; 1.
DR SMART; SM01326; PTEN_C2; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR PROSITE; PS51182; C2_TENSIN; 1.
DR PROSITE; PS51181; PPASE_TENSIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT DOMAIN 1..170
FT /note="Phosphatase tensin-type"
FT /evidence="ECO:0000259|PROSITE:PS51181"
FT DOMAIN 175..301
FT /note="C2 tensin-type"
FT /evidence="ECO:0000259|PROSITE:PS51182"
FT REGION 355..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..438
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 560 AA; 62182 MW; C6DAD3F67218FF25 CRC64;
MEEGYELDLT YITERIIAVS FPRGCSEEIY SHNLKDVTRM LKSKHADNYL IINLSEKRQD
LSRMNPKTLD TGWPDLHAPP LDKICTICKA MESWLNADPL HVAVIHCRGG KGRIGVVISS
FVHFTDVSAS ADQALDRFAM RKYYDDKVSA LMTPSQKRYV WILNSLLSGS MKINASPLFM
HCVILHGIPD FNSARVCCPY IKVYQGMQAV YSSGFYHIGP GHRDRVCIML EPAQLLKGDI
MIKCYHKSEV TSEREVIFRV QFHTGAVQGY NLMFEKEDME TANKDPRFPD YGKVELVFSE
GPEKIPGADK WKNGGDVIVD YNTADPLTRW DSYQNICDGE APHLFCFAAP RSQGLTQDRT
ANKRSPTRGD VALAQGPRTT SATSSPDHSD HALSVSSDSG LSSTSLWADK PTPVASATTT
TTTTTSVKGN QGPSQQEKVQ LKRLLSGFGL EDPSLEEMTD EGARVGVQQV VPAQVHINGD
PQPRERETDI LDDETYFIPS CFSPAPSAFL PLHSRANITK HTFSPLPTWR VLGAEIAGLL
PGFQMFSDIF RGKSAVLTCF
//
