ID A0A3Q3C8X6_HAPBU Unreviewed; 4556 AA.
AC A0A3Q3C8X6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=LDL receptor related protein 1B {ECO:0000313|Ensembl:ENSHBUP00000016732.1};
GN Name=LRP1B {ECO:0000313|Ensembl:ENSHBUP00000016732.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000016732.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000016732.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the LDLR family.
CC {ECO:0000256|ARBA:ARBA00009939}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR STRING; 8153.ENSHBUP00000016732; -.
DR Ensembl; ENSHBUT00000025345.1; ENSHBUP00000016732.1; ENSHBUG00000018946.1.
DR GeneTree; ENSGT00940000157521; -.
DR OMA; PSRNPCT; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00112; LDLa; 29.
DR CDD; cd12087; TM_EGFR-like; 1.
DR Gene3D; 4.10.1220.10; EGF-type module; 1.
DR Gene3D; 2.10.25.10; Laminin; 12.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 30.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 9.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR000033; LDLR_classB_rpt.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR22722:SF5; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1B; 1.
DR PANTHER; PTHR22722; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF14670; FXa_inhibition; 3.
DR Pfam; PF00057; Ldl_recept_a; 29.
DR Pfam; PF00058; Ldl_recept_b; 7.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00181; EGF; 26.
DR SMART; SM00179; EGF_CA; 8.
DR SMART; SM00192; LDLa; 31.
DR SMART; SM00135; LY; 33.
DR SUPFAM; SSF57196; EGF/Laminin; 6.
DR SUPFAM; SSF57184; Growth factor receptor domain; 4.
DR SUPFAM; SSF57424; LDL receptor-like module; 30.
DR SUPFAM; SSF63825; YWTD domain; 8.
DR PROSITE; PS00010; ASX_HYDROXYL; 2.
DR PROSITE; PS00022; EGF_1; 4.
DR PROSITE; PS01186; EGF_2; 3.
DR PROSITE; PS50026; EGF_3; 5.
DR PROSITE; PS01187; EGF_CA; 3.
DR PROSITE; PS01209; LDLRA_1; 19.
DR PROSITE; PS50068; LDLRA_2; 31.
DR PROSITE; PS51120; LDLRB; 17.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 4412..4435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 349..392
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 393..436
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 586..628
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 629..674
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 675..724
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 725..768
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1305..1351
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1352..1394
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1398..1444
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1626..1668
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1713..1752
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1930..1972
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1973..2015
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 2016..2059
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 2958..2998
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REPEAT 3089..3131
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 3132..3175
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 4011..4054
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 4181..4214
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 4217..4253
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 4254..4289
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 4360..4395
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 857..869
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 864..882
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 898..910
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 905..923
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 939..951
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 946..964
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 958..973
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 986..1004
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 998..1013
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1017..1029
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1024..1042
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1078..1093
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1121..1136
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2509..2527
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2543..2555
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2550..2568
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2562..2577
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2581..2593
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2588..2606
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2600..2615
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2649..2664
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2672..2684
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2679..2697
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2691..2706
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2710..2722
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2717..2735
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2795..2807
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2802..2820
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2835..2847
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2881..2893
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2888..2906
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2900..2915
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2962..2972
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 3307..3319
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3314..3332
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3347..3359
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3354..3372
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3366..3381
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3406..3421
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3446..3461
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3466..3478
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3473..3491
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3485..3500
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3505..3517
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3512..3530
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3524..3539
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3543..3555
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3550..3568
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3562..3577
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3585..3597
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3592..3610
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3604..3619
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3643..3658
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3666..3678
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3673..3691
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3737..3749
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3744..3762
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 4185..4195
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4221..4231
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4243..4252
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4257..4267
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4279..4288
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4362..4372
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4366..4383
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4385..4394
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 4556 AA; 507841 MW; 335C6DD5C5A3EF5A CRC64;
MSWRMFSAET CAHACVCSVP SPHAASLLSP SPPLCSRHPD ILCDVGEFHC HNHDTCVPED
WLCDGEPDCP DESDETDHVC AREVVIRCPL NHMQCTGTKK CIHFNKLCNG ARDCDDGYDE
GVHCRELLSA CHELRCRYGC VMTRNGTFCF CADGFEVGED GTSCRDHDEC AMYGACSQTC
TNTYGSYRCS CTEGYILQPN RISCKAKQDP GDSRPALLIG GSDRIVVTHL NGSGLQPLRS
LRTNWTLALD FQQNQESVCW VLSSESSGQL RCAVTRSLRG FTREQEIRTQ QSLQHVEQMA
IDWLTGNFYF VDRVTDKIFV CDSGGDTCVT VLQLDLLNPK GIALDPLMGM LFFTDYGNVA
KVERCNMDGT NRTRLVDYKI EQPTAVALDV VKKLVYWADA YLDYIDVVDY QGKNRHTVIH
GSQVSYIYSL AVFEDYLYAI HSDPSKGSSS AELLQIHRFN ITADSRTLGS LGNSKGLRVY
HKLTQPKVRS HACEMDSYGK PGGCSHICLL SGSYKSRTCR CRTGYSLGFD GMSCKKPKND
IFLFYGKGRP GVIRGLDMNI KSSDEHMVPI EDLVNPRAID YHAELGHVYF ADTTSFLIGR
QKIDGSSRET ILKDELDNVE GISVDWIGNN LYWTNDGYRK TISVARLDRA SQTRKTLLEG
NMSHPRAIVV DPLNSWMYWT DWEEDEVNDS IGRIEKAWMD GSNRRIFVTS NMLWPNGLTL
DHSSSTMYWC DAYYDHIEKI HLNGTGRMVV YSGKELNHPF GISHYRNFIF WTEYMNASVF
QLDLTNGDIT LLRSERPPLF GLRVYDAQSQ QGDNACSVNY GGCTTLCLAI PGGRVCACAD
NQVLEKNNVT CAEPQRCKSD EFQCRNQRCI RALWKCDGDD DCLDGSDEEI QSCYNHTCPL
NQFKCSNNRC IPKRWLCDGT NDCGNNEDES NNTCSAQPCQ AEQFSCQNGR CIPRSWSCDR
EDDCGDKSDE ISCVFPTCEP VTQFSCSSGR CISVEWHCDS DDDCGDGSDE VGCIQSCSNT
HFQCSNGRCI PDHWACDGDN DCGDLSDETL TCRGGPACNA EEFHCVTDGT CIPERWSCDG
DKDCEDGSDE KDCEGTKRMC DPKAKFTCKD TGKCITKSWV CDGDIDCEDR SDEESCESAA
CKPPKYPCAN DSSVCLTPDK ICNGKVDCAD RSDEGPICDL CLVARGGCSH QCTVAPGKGV
VCSCPPGLHL DSSNKTCEVV DYCSRHLKCS QVCEQYKTTV KCSCYPGWML DSDGDSCHST
DPFEAFVIFS IRHEIRRIDL HKRDYSLLVP GLRNTIALDF HFNHSLLYWT DVVEDKIYRG
KLSESGGVTG IEVVVQHGLA TPEGLAVDWI TGKLYWIDSN LDQIEVAKLN GEMRTTLIAG
GMEHPRAIAL DPGQGYVGIL FWTDWDATFP RIEAASMSGG GRHVVFKDME IGAWPNGLTL
DHLEKRIVWT DARSDAIFSA LYDGTGVIEI LRGHEYLSHP FAVSLFGGSV YWTDWRTNTL
ARANKWTGQN VTVIQKTSAQ PFDLQIFHPS RQPQVPNPCE KNDGRGPCSH LCLINYNRTA
SCTCPHLMKL STNKQSCFAL KRFLLYVRRS EIRGVDIDDP YMNVMTALTV PDIDDVTVVD
YDSQEERIYW ADIKTQTIKR AFVNGTQLET VISLDIVNCR GLALDWLSKN LYWLSSENDE
SQINVARFDG SLKTSIIHGI DKPRCLVVHP AKGKMYWTDG NTINMASMDG SNSKVLHQNQ
RDPVGLSIDY AANKLYWISS TNGTINRCNL DGSGLEVLET VKRELAKGTA LAVMGGKLWW
ADEESGRLGT VTKRDGRNLV VLRNKTGGVV HMKVYDRDSQ KGKNQCQVNN GGCSQLCFPT
SENTRSCSCT VGYNLRSDRT SCEGVDSFLM YSIHEGIRGI ALDPNDNSEA LMPITGTLFA
VGVDFHAGND TVYWTDMGLN RISRAKRDQT WREDVITTGI SRVEGIAVDW IAGNLYWTDH
GFNLIEISRL NGAYRSVVIS EGLDQPRAIA VHPQKGYLFW TEWGQNPCIG RSRLDGSDQV
TLVSSGITWP NGISIDYEEN TLYWCDARTD KIERINLETG ESREIVLSMA NVDLFSVAVF
GPYIYWSDRA HSNGSIRRGL KTDPSEAVTM RSGLGVNLKD VTVFTRGREK GTNPCARSNG
GCQQLCFHLG SGRRTCSCAH GRLAEDGFAC ERYEGYLLYS ERTILKSIHL SDENDLNSPV
QPFENPAFFK NVITLAFDYS QETAGANRIF FSDVHFGNIQ MINDDWTGRS IIAENVGSVE
GLAYHKGWDT LYWTSSTTST ITRQTVDQSQ AGAISRQAVV TLSEEDHPHV LALDECQRSV
VFLIMLRTTA LTGLNLHIFK LLLCTTEPLI SKIPLIAKIL EKIVAKQLTV IIKSGPGNFY
GLAIYADFIY WSDWARRSVL RSNKYTGGDT KVLRADIPHQ PMGIIAVAKD TNNCQLSPCR
HMNGGCGDLC LLTPYGRVNC TCRGERVLLD DNRCVSENSS CNIYTEYECG NGECIDFQLT
CDGIAHCKDK SDEKMQYCDN RSCRKGFRPC YNQRCVATNR FCDGIDDCGD NSDEALCNVT
CGSSESSCKD GSCVPSSAWC NQVIDCADAS DEKNCNHTDC SHFYKLGVKE KDFISCNSTS
LCIHASWICD GANDCGDYAD ETNCQGERRH KCEEGHFACP SGNCISSVWL CDGQKDCEDG
ADEFQCDSSC LWNQFACSKN KCIAKQWLCD GENDCEDGLD ESVQICGTVT CAPGLFSCPG
SYACVPKRWL CDGERDCPDG SDELSAAGCA PNNTCDDSSF RCRNKACIPQ RFVCDHDNDC
GDGSDESVEC VYRSCGSEEF RCGDGRCLLS SQWECDGYAD CPDLSDELPL NLKCLAAGSL
CNGSFFMCSN GRCISQGNLC DGKDDCGDRS DERNCNVNEC LNRRVSGCTQ DCQDLPVGYK
CKCWPGFYLK DDGRTCVDVD ECSTTLPCSQ RCINTYGSYK CLCVDGYEAL ERNPNTCKAL
SAEEPFLIMA DHHEIRKLSV DGSNYTILKQ GLYNIIHLDF DYKKEFIYWV DSTRPSGRKI
NRMRLNGSDL KIVHRTAVPS ALAVDWIGKN LYWCDAEKKT MEVSKANGLY PTVLISSGLK
NPTDLALDPQ TGYIFWVDCC DPPHIGRIGM DGRGQTVIID TEIYSPTALT IDYTNKRLYW
ADDNHILFAS MDGAQRRKVS YDHIQGVMAL TLFEDFVYWT DGKSKSLRRA HKTTGAQGIE
LLNSWQAIKS IKVYHSLRQP EVPKHQCQIA NGGCSHLCLL SPGGEHKCAC PTNFYLAADN
KTCLSNCTSS QFRCGTDECI PFWWKCDTVD DCGDGSDEPA DCPEFKCQPG RFQCGTGLCA
LPPFICDGEN DCGDNTDEAN CETYICLSGQ FKCTGKQKCI PLNLRCNGQD DCGDGEDETD
CPESTCSPDQ FQCKASMHCI SKLWVCDEDP DCADGSDEAD CDEKTCGPHE FRCENNNCIP
DHWRCDSQND CGDNSDEENC KPVTCNHKDF ACANGDCISS RFRCDGDYDC LDNSDEKGCE
AHCSDDQFRC HNNLCISMKW LCDGQEDCKM GEDEKTCQET VVPSCSVNEY VCTSGGCVSA
SLRCDGHDNC LDGSDEIGCV KECREDEFLC LNRAHCIPRR WRCDEVLDCM DHSDEENCGQ
GRSFFCRADE FICNNTLCKL HTWVCDGKDD CGDNSDEDAD MCGGLRLSLT RISFEADDAY
FIDLCFSISR EGTPRPCGKT EFSCSNRRCV PIQLQCDLFS DCGDGGSDEQ DCKAYVCGKK
TNPCGEDAIC NQTNANSICQ CKPGFKRNQK TGQCEEINEC LQFDACPHYC ANTKGSYKCS
CDRNFKEING NCVARGPEER VFYVSNDTEI RSFLYPFNQS LGYRLPTHIE DNARIIGMDV
LFHHQKFIWA TQFNPGGIFY KDNLERSQSK TNVRNICSDF RRPRDISADW ITGNIYWTDH
SRMHWFSYYT AHWTKLRYSI NVGQLKGPNC TRLITDIPGE PYAIAVNPTR GMMYWSVIGD
HSQIEESAMD GSLRRVMLDK NLRRPTGLAI DYFNQRIYWA DPELSQIGSM RLDGSDPLVT
IRISQPYRID IFEDYIYGTG LKHEVFKIHK YGKQAVEFLS LGVEKPTNVF ISHRYKQQDG
PNPCSRMSCD FMCLLNPTGA RCTCPEGKVL VNGTCNDVNV SGELCRPPCE NGGRCLANEK
GDWRCYCWPD FSGERCEVNH CTDYCLNGGT CMGSPLGKPT CRCPVGFSGP FCEKRICDNY
CLNGGTCDVT QGNQPVCRCM AEYTGDRCLY HICHHYCVNS KACTLSSSGY VECVCPARFE
GNKCEVDKCL RCHGAPCLIN EETGEVVCNC TNGRIAPSCQ LCDGYCYNGG TCHLDPDTNL
PFCQCSANWA GTQCERPAPK SSRSDNMSGG SIAIIVPLVL LVILIVMVVA GVYICRRRQR
GKRVQRQPMT NGGINVEIGN PSYNMYEVDH DNHADAGSLL RPNFTLDPHK VGVCVSRVLN
NTSFLSTSMS PMNYSNPVYA KIYIDGQNCR KPVISIDERR ELLPKKLEGT IHETAA
//
