ID A0A3Q3CHU5_HAPBU Unreviewed; 508 AA.
AC A0A3Q3CHU5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Interleukin-1 receptor type 1-like {ECO:0000313|Ensembl:ENSHBUP00000022827.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000022827.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000022827.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the interleukin-1 receptor family.
CC {ECO:0000256|ARBA:ARBA00009752}.
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DR AlphaFoldDB; A0A3Q3CHU5; -.
DR STRING; 8153.ENSHBUP00000022827; -.
DR Ensembl; ENSHBUT00000012656.1; ENSHBUP00000022827.1; ENSHBUG00000003326.1.
DR GeneTree; ENSGT01090000259985; -.
DR OMA; LRYHMPP; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0004908; F:interleukin-1 receptor activity; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR015621; IL-1_rcpt_fam.
DR InterPro; IPR004074; IL-1_rcpt_I/II-typ.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11890; INTERLEUKIN-1 RECEPTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11890:SF47; INTERLEUKIN-1 RECEPTOR TYPE 1-LIKE; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR01536; INTRLKN1R12F.
DR PRINTS; PR01537; INTRLKN1R1F.
DR SMART; SM00409; IG; 2.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50835; IG_LIKE; 2.
DR PROSITE; PS50104; TIR; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius}; NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 279..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..86
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 107..194
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 321..486
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 508 AA; 57596 MW; CF83190FCEE10101 CRC64;
MTNSCSPVAL SPTDHRGEID TFHVSAGHFF LLNCYTAEAH DVVIWSRGES KDNLSLPTGV
EVRDRLLWFL PVQMSHNGSY TCQIRNQPGV LLRRLKFWVS VSSGECPYTV ESISITKGVS
DSLPCKQKEI FGLNSVVNVR WMKDCQLIQR QGKPISVDMK GNMRLPQASE EDNGKYTCLI
DINLDGRNYT ASRSILLTVK DEKVFVEPQL VTPDKQEITV ELGLRVELQC LAFIGYSEDN
ESSLHWTVGK DFAEDLEEIN TCLTFVSFLS PADRSSFHMS WAFCLSASLA VLALAACFFF
FKVNLILAYR DLLILSVPDG KLYDAYVSFI HSNAMSSDEG TRFAMQILPE KLEEQYGYSL
FIRGRDDCPG EAIHDATAAA MHQCRRLLII LSPEGKTEES TCICDNQSQV WYEQKVGLHD
ALTKNDPRVI LVEIDGPVDY SHLPESLRYI KRKQGALKWK KDFLATHKFT ELYSKRNFWI
NLRYHMPPVP TRRLQTIPGL NISANMSM
//
