ID   A0A3Q3CKQ1_HAPBU        Unreviewed;      1169 AA.
AC   A0A3Q3CKQ1;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Myelin transcription factor 1 like {ECO:0000313|Ensembl:ENSHBUP00000024762.1};
GN   Name=MYT1L {ECO:0000313|Ensembl:ENSHBUP00000024762.1};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000024762.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000024762.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the MYT1 family.
CC       {ECO:0000256|ARBA:ARBA00010194}.
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DR   AlphaFoldDB; A0A3Q3CKQ1; -.
DR   Ensembl; ENSHBUT00000007715.1; ENSHBUP00000024762.1; ENSHBUG00000006413.1.
DR   GeneTree; ENSGT00940000155671; -.
DR   Proteomes; UP000264840; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 4.10.320.30; -; 5.
DR   InterPro; IPR013681; Myelin_TF.
DR   InterPro; IPR002515; Znf_C2H2C.
DR   InterPro; IPR036060; Znf_C2H2C_sf.
DR   PANTHER; PTHR10816:SF11; MYELIN TRANSCRIPTION FACTOR 1-LIKE PROTEIN; 1.
DR   PANTHER; PTHR10816; MYELIN TRANSCRIPTION FACTOR 1-RELATED; 1.
DR   Pfam; PF08474; MYT1; 1.
DR   Pfam; PF01530; zf-C2HC; 5.
DR   SUPFAM; SSF103637; CCHHC domain; 5.
DR   PROSITE; PS51802; ZF_CCHHC; 5.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU01143}.
FT   DOMAIN          604..854
FT                   /note="Myelin transcription factor 1"
FT                   /evidence="ECO:0000259|Pfam:PF08474"
FT   REGION          1..159
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          183..211
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          314..347
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          470..491
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          645..696
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1041..1110
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1..17
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        55..103
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        113..146
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        314..339
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        470..490
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        669..693
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1169 AA;  129298 MW;  CE24DA8D0AD23B83 CRC64;
     MCVRSHDTHE RSHTRAARGA RVYGCPLAKK RKSIDRQTLE TSPKRSTYLD DMDNSTMEEC
     YETDGTEEMD DREEEEEEGA VEDEEEEGEV EEEEEEEVEA YMDYNVEQME HEDGEVETGD
     GEGEEEAEEE EVEVEQEEEE EGDEGRVVEK DDNNNDEYEN YDELVAKSLL NLGKIAEDAA
     NRAMTESEMN SNSSNSEEEE GDEPQRGDLS LDVDSDVVRE TVDSLKLLAQ GHGAVLSDNL
     DGQEFEDGTA NNRDAIDCTN NGVNAHNGGN GQIKTTSNGQ IENSDEEVCL SSLECLRNQC
     FDLARKLSET KSIDRNAPSQ QNHFSCEDPN QQPQHHGYGD FHSSQDDRRM LDRNYSDMDN
     LMKLEEQLSP RSKAFSSCAH DDRYHTHHRD FDEDTASVTS DRSEEVFDMT KGNLSLLEKA
     IALESERAKA MRDKMAAEAA RRDGVRYGHE DHGPRHGYGV ERKARLPDGM KKPFYHKDAS
     RVDKKESRCP TPGCDGTGHV TGLYPHHRSL SGCPHKDRVP PEIVAMYENV LKCPTPGCTG
     RGHVNSNRNS HRSLSGCPIA AAEKLAKAKE KHQSCDGPKS NQASDRVLRP MCFVKQLDYP
     QYGYKNNVST STPRSNLAKE LEKYSKTSFD YSAFDGGNNH HVYGKRAIAP KVHGQRDTSP
     KGYDAKRYCK NSSSASSTTS TYAPSSSGSS LSCGGGGGRG GSSFDYSHDM EAAHMAATAI
     LNLSTRCREM PHDMAGKPQD LCSQVGPGLD VDENGTLDLS VSKRLCSGGA GDSVLTPLEP
     MSPQRQAALL GSRCYGMGDA ADCWDLPVDY TKIKHIDEDE KEPDDLDPFH DLLDDRSYTT
     DVNMPSPKPK FLQCKETKKD LITLSGCPLA DKSIRSMLAN NAQELKCPTP GCDGSGHITG
     NYASHRSLSG CPRARKSGIK IIHSKENKED QEPIRCPVPG CDGQGHVTGK YASHRSASGC
     PIAAKRQKDG YLNGIQFTWK SGKTEGMSCP TPGCDGSGHV SGSFLTHRSL SGCPRATSAM
     RKARLSGVEM LTIKQQRASN GLEHDEEIKQ LDEEIKDLSE SNSQVEADMI KLRTQITTME
     SNLKSIEEEN KVIEQQNESL LHELANLSQS LINSLANVQL PHMEPISEQN FDAYVTTLTD
     MYTNQEQYQS PENKALLENI KQAVQGIQV
//