ID A0A3Q3E1U4_9LABR Unreviewed; 550 AA.
AC A0A3Q3E1U4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLBEP00000001265.1};
OS Labrus bergylta (ballan wrasse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrus.
OX NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000001265.1, ECO:0000313|Proteomes:UP000261660};
RN [1] {ECO:0000313|Ensembl:ENSLBEP00000001265.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC Evidence={ECO:0000256|ARBA:ARBA00001962,
CC ECO:0000256|RuleBase:RU003974};
CC -!- SIMILARITY: Belongs to the lipoxygenase family.
CC {ECO:0000256|RuleBase:RU003974}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
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DR AlphaFoldDB; A0A3Q3E1U4; -.
DR STRING; 56723.ENSLBEP00000001265; -.
DR Ensembl; ENSLBET00000001355.1; ENSLBEP00000001265.1; ENSLBEG00000000959.1.
DR GeneTree; ENSGT00940000155191; -.
DR InParanoid; A0A3Q3E1U4; -.
DR Proteomes; UP000261660; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR GO; GO:0034440; P:lipid oxidation; IEA:InterPro.
DR Gene3D; 3.10.450.60; -; 1.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 1.
DR InterPro; IPR000907; LipOase.
DR InterPro; IPR013819; LipOase_C.
DR InterPro; IPR036226; LipOase_C_sf.
DR InterPro; IPR020834; LipOase_CS.
DR InterPro; IPR020833; LipOase_Fe_BS.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR PANTHER; PTHR11771; LIPOXYGENASE; 1.
DR PANTHER; PTHR11771:SF161; POLYUNSATURATED FATTY ACID LIPOXYGENASE ALOX15B; 1.
DR Pfam; PF00305; Lipoxygenase; 1.
DR Pfam; PF01477; PLAT; 1.
DR PRINTS; PR00087; LIPOXYGENASE.
DR SMART; SM00308; LH2; 1.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 1.
DR SUPFAM; SSF48484; Lipoxigenase; 1.
DR PROSITE; PS00711; LIPOXYGENASE_1; 1.
DR PROSITE; PS00081; LIPOXYGENASE_2; 1.
DR PROSITE; PS51393; LIPOXYGENASE_3; 1.
DR PROSITE; PS50095; PLAT; 1.
PE 3: Inferred from homology;
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964, ECO:0000256|RuleBase:RU003974};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU003974};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU003974};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003974};
KW Reference proteome {ECO:0000313|Proteomes:UP000261660}.
FT DOMAIN 2..118
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 172..550
FT /note="Lipoxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51393"
SQ SEQUENCE 550 AA; 62288 MW; 9F280FB0CC10A6D3 CRC64;
MVKYQVTITT GSIAGASTFN HIFIKLVGTD GESDRSWLIN FKGALAFTPG AVSLKYFESD
GNPQLGCLLL VRLPLFPEDS WFPTKVEVKS PEGDTYNFPV YRWITDSALS NFDLSVFLSW
DVYKEGIPHC MKADNPLSLP CEVRFSFTKT SEFLFTAASG SALLFPDYVQ EHWKEDAFFG
YQFLNGINPM LIRRCSVLPE NFPVTDGMVR LPDQCSLEDE MKKGNIYLCD YKRLDGVEAN
IINGKKQYLM APLVLLHKTP EDKMMPIAIQ LKQTPGEDNP IFFPTDSEYD WLMAKIFVRS
ADFSEHQLNV HLLRTHLLAE VFAVSLLRNV PMVHPLYKLL IPHTRYTLQI NFLARLALIS
DTGVFTQFSA SGGEAMLPIL KRSLSSVTYS SLCIPDDIAE RGLEAVPNYY YRDDGLKLWE
IIHRFVQGIL SYYYKRDAEV QQDSELQKWI SDIYEHGFLS QPCPGIPKSL TTVVELIKFV
TMVIFTGSGQ HSAVNTGQYD YGGWMPNTPI SLEATMLQTF PDVNVTVQGM STVWLLSKQS
SDFVSIDDFM
//
