ID A0A3Q3EAP3_9LABR Unreviewed; 1960 AA.
AC A0A3Q3EAP3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Myosin heavy chain, fast skeletal muscle-like {ECO:0000313|Ensembl:ENSLBEP00000003116.1};
OS Labrus bergylta (ballan wrasse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrus.
OX NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000003116.1, ECO:0000313|Proteomes:UP000261660};
RN [1] {ECO:0000313|Ensembl:ENSLBEP00000003116.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR STRING; 56723.ENSLBEP00000003116; -.
DR Ensembl; ENSLBET00000003282.1; ENSLBEP00000003116.1; ENSLBEG00000002325.1.
DR GeneTree; ENSGT00940000164626; -.
DR InParanoid; A0A3Q3EAP3; -.
DR Proteomes; UP000261660; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 5.
DR Gene3D; 1.20.5.370; -; 4.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF44; MYOSIN-13; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000261660};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1925..1945
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 33..82
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 86..778
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 655..677
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT COILED 846..1146
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1183..1646
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1675..1913
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 179..186
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1960 AA; 226346 MW; 0691657D9C98E730 CRC64;
MSSDAEMAQY GPASIFLRKP EKERVEAQNR PFDARTACFV PDAKELYIKG VIQKRDGEQV
TVKTAADEIV TVKEEDVHPM NPPKYDKIED MAMMTHLNEP SVLFNLKERY AAWMIYTYSG
LFCATVNPYK WLPVYDPQVV AAYRGKKRME APPHIFSVSD NAYQNMLTDR ENQSVLITGE
SGAGKTVNTK RVIQYFATIA VAGGDKKEHS SGKIQGTLED QIISANPLLE AFGNAKTVRN
DNSSRFGKFI RIHFGTTGKL ASADIETYLL EKSRVTFQLT EERSYHIFYQ IMTGHKPELI
EMLLITTNPY DFPLISQGQI AVASIDDREE LLATDTATDI LGFTNEEKVG IYKLTGAVLH
YGNMKFKQKQ REEQAEPDGT EVADKVAFLM GLNSADLLKG LCYPRVKVGN EYVTKGQTVP
QVTNAVGALA KSVYEKMFLW MVIRINEMLD TKQPRQFFIG VLDIAGFEIF DFNSMEQLCI
NFTNEKLQQF FNHHMFVLEQ EEYKKEGIDW EFIDFGMDLA ACIELIEKPM GIFSILEEEC
MFPKASDTSF KNKLYDQHMG KNMAFQKPKV VKGKPEAHFS LLHYAGNVDY NISGWLEKNK
DPLNESVVQL YQKSPMKLLA YLYASFSGGD AGGKKGAKKK GGSFQTVSAV FRENLGKLMT
NLRSTHPHFV RCLIPNEIKT PGIMDNHLVI HQLRCNGVLE GIRICRKGFP SRILYADFKQ
RYRILNASAI PEGQFIDGKK ASEKLLGSID LDHTQYRFGS TKVFFKAGLL GTLEELRDEK
LVSLVTQTQA LCRGYVMRKE YNNLIYNLRS FMNVKHWPWM KLFFKIKPLL KSAETEKEMA
TMKEDFVKCK DDLSKLESKR KELEEKMVSL LQEKNNLLLQ VQSDSENLCD AEERCEGLIK
SKIQLEAKLK EVTERLEDEE EMTAELTAKK RKLEDECSEL KKDIDDLEMT LAKVEKEKHA
TENKVKNLME ELAGQDENLG KLTKEKRALQ EAHQQVLDDL QAEEDKVNSL SKAKTKLEQQ
VDDLEASLEQ EKKIRMDLER AKRKLEGDLK LSQESIMDLE NDKQQSEEKI KKKEFENNEL
LSKISDEQAI NNQLQKKMKE LHARIEELEE EVEAERAMRA KIEKQRSDLS REIEEISERL
EEAGGATAAQ IEMNKKREAE FLKLRRDLEE STLHHEATNA ALRKKQADSM AELGEQIDNL
QRIKQKLEKE KSELKMEVDD LAVNMETVAK TKVNLEKTCR SFEDQLIELK TKNDECMRQI
NDLSNQRARF QTENAEFSRQ MEERESLISQ LTRGKQGFTT QIDELKRLIE EETKAKNALA
HSVQSARHDC DLLREQYEEE QEAKAELQRT LSKANTEVAM WRNKYETDAI QRTEELEEAK
KKLAQRLQEA EEQIEAINSK CASLEKTKQR LQNEMEDLMV DVERSNSLAA TLDKKQRNFD
KILAEWKQKF EESQAELESS QKESRSLSTE LFKLKNSYEE ALDHLETMKR ENKNLQQEIA
DLTEQLGETG KTVHELEKFK KTVETEKYDM QTSLEEAEAT LEQEESKILR AQMELNQVKA
EVDRKLAEKD EEIEQMKRNQ QRVMESMQNT LDAEVRSRND ALRLKKKMDG DLNEMEIQLS
HANRQAAESQ KQLRNLQGQL KDAQIHLDDS LRGHDDMKEQ VGMMERRTTL MQAEIEELRA
VVEQSERSRK LAEQELVDTS ERAGLLHSQN TSLLNTKKKL EADVTQFHSE IEEAVQEARN
AEEKAKKAIT DAAMMAEEMK KEQDTCAHLE RMKKNLEVTV KDLQHRLDEA ENLAMKGGKK
QLQKLEARVR ELETELEAEQ KRSSDAIKGV RKYERKIKEL SYQTDEDKKN NIRLQDLVDK
LQIKMKAYKR NAEEAEEQCN VHMARFRKAQ HELEEAEERA DVAESLANKM RVKSREIGAK
VPCGVFFFFL LFIIFFFYFF SSLLFKHYVL FLFYMHSNYS
//
