ID   A0A3Q3EMH9_KRYMA        Unreviewed;       699 AA.
AC   A0A3Q3EMH9;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Interleukin-1 receptor accessory protein-like 1-B {ECO:0000313|Ensembl:ENSKMAP00000003047.1};
OS   Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX   NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000003047.1, ECO:0000313|Proteomes:UP000264800};
RN   [1] {ECO:0000313|Ensembl:ENSKMAP00000003047.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the interleukin-1 receptor family.
CC       {ECO:0000256|ARBA:ARBA00009752}.
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DR   RefSeq; XP_017265773.1; XM_017410284.1.
DR   AlphaFoldDB; A0A3Q3EMH9; -.
DR   Ensembl; ENSKMAT00000003110.1; ENSKMAP00000003047.1; ENSKMAG00000002292.1.
DR   GeneID; 108232468; -.
DR   CTD; 568868; -.
DR   GeneTree; ENSGT01090000260076; -.
DR   OrthoDB; 3994459at2759; -.
DR   Proteomes; UP000264800; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd00096; Ig; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR015621; IL-1_rcpt_fam.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR11890:SF46; INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN-LIKE 1-A; 1.
DR   PANTHER; PTHR11890; INTERLEUKIN-1 RECEPTOR FAMILY MEMBER; 1.
DR   Pfam; PF13927; Ig_3; 1.
DR   Pfam; PF01582; TIR; 1.
DR   PRINTS; PR01537; INTRLKN1R1F.
DR   SMART; SM00409; IG; 3.
DR   SMART; SM00408; IGc2; 2.
DR   SMART; SM00255; TIR; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 3.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50835; IG_LIKE; 3.
DR   PROSITE; PS50104; TIR; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius}; NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..699
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018709532"
FT   TRANSMEM        362..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          6..136
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          164..234
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          244..350
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          405..561
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   699 AA;  80344 MW;  1EA1B8D3419BD642 CRC64;
     MTPPSPLLIL LYFTLSKSVK VVSKRGSVDG CTDWSVDYLK YRVLQGEPVR LKCALFYGYI
     RANYSQAQSV GLSLMWYRSS GLGHSDFEEP ISFDGVRMSK EEDAIWFRPA DLQDVGLYSC
     VLRNSTYCMK VSMSLTVAEN DTDLCYNSNM RRNEKAELSK SKDILCPDID DYVEPGKEPE
     ITWYKECHPK QWRASIIQKR DILSIQEVKE DDIGNYTCEV QFGGFVVRRT TELTVTAPLT
     DKPPKILFPT ENKISTMELQ LGSPLNLTCR AFFGYSGDVS PLIYWMKGEK FIEDLDEERV
     QESDIKLVRD HLGEQEVAIS LTIDSLEEED LGNYSCYVEN GNGRRQATIQ IFRRELMYTV
     ELAGGLGAIL LLLIFLISLY KCYKIELMLF YRRHFGSEDV DGENKDYDAY LSYTKVDPDQ
     WSQETREEER FALEILPDVL EKHYGYKLFI PDRDLIPTGT YIEDVARCVD QSKRLIIVMT
     PNYVVRRGWS IFELETRLRN MLVTGEIKVI LIECAELRGI MNYQEVEALK HTIKTLTVIK
     WRGPKSNKLN SKFWKQLQYE MPFRRTEPML THEPALDVSE QGPFGELQTV SAISMAAATS
     TAMATAHPEL RSSFHNTYHT TMRQKHYYRS YEYDIPPGGT LPPLSSLGNQ HTYCNIPLTL
     LNGQRPPGKT REHSLEEPHA NNAMLPLLPR ETSISSVIW
//