ID A0A3Q3EN24_9LABR Unreviewed; 507 AA.
AC A0A3Q3EN24;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Cytokine-like nuclear factor N-PAC {ECO:0000256|ARBA:ARBA00034140};
DE AltName: Full=Glyoxylate reductase 1 homolog {ECO:0000256|ARBA:ARBA00030287};
DE AltName: Full=Nuclear protein NP60 {ECO:0000256|ARBA:ARBA00032038};
DE AltName: Full=Putative oxidoreductase GLYR1 {ECO:0000256|ARBA:ARBA00034145};
OS Labrus bergylta (ballan wrasse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrus.
OX NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000008873.1, ECO:0000313|Proteomes:UP000261660};
RN [1] {ECO:0000313|Ensembl:ENSLBEP00000008873.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC -!- SIMILARITY: Belongs to the HIBADH-related family. NP60 subfamily.
CC {ECO:0000256|ARBA:ARBA00007598}.
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DR AlphaFoldDB; A0A3Q3EN24; -.
DR STRING; 56723.ENSLBEP00000008873; -.
DR Ensembl; ENSLBET00000009352.1; ENSLBEP00000008873.1; ENSLBEG00000006880.1.
DR GeneTree; ENSGT00940000156435; -.
DR InParanoid; A0A3Q3EN24; -.
DR OrthoDB; 103196at2759; -.
DR Proteomes; UP000261660; Unplaced.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd05836; PWWP_GLYR1; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR035501; GLYR1_PWWP.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR000313; PWWP_dom.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50812; PWWP; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Reference proteome {ECO:0000313|Proteomes:UP000261660}.
FT DOMAIN 8..66
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 92..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..143
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 507 AA; 55430 MW; 99DF7F93DDCC907E CRC64;
MATVHLRIGD LVWGKLGRYP PWPGKVVSPP KDLKKPRGKK CHFVKFFGTE DHAWIKVEQL
KPYHAHKEEM IKINKGKRFQ QAVDAVEDFL KKAKGKEQNS DGKGESKGKK TPSKPLKILE
EEDEDLSALK DPSEKDLTDS DPEPSTIERL GAGPGSGFKW ESSPVKDDPH FHHFLLSQSD
KPASSMEPIS KRLKIIEEDT GSTSIQAADS TAINGSITPT DKRIGFLGLG LMGSGIVSNL
LKMGHVVTVW NRTAEKCDLF IQEGARLGRT PAEVASMCDI TFSCVSDPKA ARDLVMGPSG
VLQGIRPGKC YVEMSTVDPE TITELSQVIT SRGGRFLEAP VAGSQQLSND GMLVILAAGD
RTVYEDCSSC FQAMGKTSFF LGEAGNAARM MLILNMVQGS FMATIAEGLT LAQATGQSQQ
TFLDILCQGQ MASTFVDQKC QNILQGNFKP DYYLKHIQKD LRLAISMGDM ANHPTPMAAA
ANEVYKRAKA LDQSDNDISA VYRAYIH
//
