ID A0A3Q3ET29_9LABR Unreviewed; 462 AA.
AC A0A3Q3ET29;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Kringle-containing protein marking the eye and the nose {ECO:0000256|ARBA:ARBA00032328};
OS Labrus bergylta (ballan wrasse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrus.
OX NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000010528.1, ECO:0000313|Proteomes:UP000261660};
RN [1] {ECO:0000313|Ensembl:ENSLBEP00000010528.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00121}.
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DR STRING; 56723.ENSLBEP00000010528; -.
DR Ensembl; ENSLBET00000011075.1; ENSLBEP00000010511.1; ENSLBEG00000008130.1.
DR Ensembl; ENSLBET00000011093.1; ENSLBEP00000010528.1; ENSLBEG00000008130.1.
DR GeneTree; ENSGT00940000158390; -.
DR Proteomes; UP000261660; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR GO; GO:0048903; P:anterior lateral line neuromast hair cell differentiation; IEA:Ensembl.
DR GO; GO:0001889; P:liver development; IEA:Ensembl.
DR GO; GO:0048916; P:posterior lateral line development; IEA:Ensembl.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00041; CUB; 1.
DR CDD; cd00108; KR; 1.
DR Gene3D; 2.40.20.10; Plasminogen Kringle 4; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR000001; Kringle.
DR InterPro; IPR013806; Kringle-like.
DR InterPro; IPR018056; Kringle_CS.
DR InterPro; IPR038178; Kringle_sf.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR002889; WSC_carb-bd.
DR PANTHER; PTHR24269; KREMEN PROTEIN; 1.
DR PANTHER; PTHR24269:SF16; PROTEIN SLG1; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF00051; Kringle; 1.
DR Pfam; PF01822; WSC; 1.
DR PRINTS; PR00018; KRINGLE.
DR SMART; SM00042; CUB; 1.
DR SMART; SM00130; KR; 1.
DR SMART; SM00321; WSC; 1.
DR SUPFAM; SSF57440; Kringle-like; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS01180; CUB; 1.
DR PROSITE; PS00021; KRINGLE_1; 1.
DR PROSITE; PS50070; KRINGLE_2; 1.
DR PROSITE; PS51212; WSC; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Kringle {ECO:0000256|ARBA:ARBA00022572, ECO:0000256|PROSITE-
KW ProRule:PRU00121}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261660};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..462
FT /note="Kringle-containing protein marking the eye and the
FT nose"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041126496"
FT TRANSMEM 383..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..110
FT /note="Kringle"
FT /evidence="ECO:0000259|PROSITE:PS50070"
FT DOMAIN 112..206
FT /note="WSC"
FT /evidence="ECO:0000259|PROSITE:PS51212"
FT DOMAIN 210..317
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT REGION 323..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..365
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 462 AA; 50887 MW; F38507D1707ACDD5 CRC64;
MDSWTVSAAL FLAGVISSAA FSHFDTECYT ANGEDYRGFQ NQTSLHGGKP CLFWNETFQH
PYNTLKYPNG EGGLGRHNYC RNPDGDVQPW CYIADHEDGI YWRYCDIPTC QMPGNLGCFR
DSGDPPTLSG TSETSNKLTI QNCISFCRKQ RYKLAGMESG YACFCGNEVD LRDHGESPSM
ECNHVCFGDH TQPCGGDGWV IIFDTRVGSC GGNYSSPSDV IYSPDFPDKY SAGRVCYWTI
QVPGSSAILF NFTFFDISDQ TDMVELLDGY TNQVVARFDW RSPPRELVNV TGDFVILYFF
SDRTNQAQGF ALLYQAIGSQ DSRTMEAEGE GEENGEDVSS TAGPQLAGSV TERSNSTSNG
RSSQIRYVIT SSPGKPEHNM PVWTIYALAA LLILTVIAMV AKLLLHITVK SPSIPAVSSS
DSCSQSTASS EPWIILYRPS TISLFKKKLK NHHGDLSPLV GN
//
