ID A0A3Q3F0S3_9LABR Unreviewed; 626 AA.
AC A0A3Q3F0S3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Polyadenylate-binding protein {ECO:0000256|RuleBase:RU362004};
DE Short=PABP {ECO:0000256|RuleBase:RU362004};
OS Labrus bergylta (ballan wrasse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrus.
OX NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000013194.1, ECO:0000313|Proteomes:UP000261660};
RN [1] {ECO:0000313|Ensembl:ENSLBEP00000013194.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Binds the poly(A) tail of mRNA.
CC {ECO:0000256|RuleBase:RU362004}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU362004}.
CC -!- SIMILARITY: Belongs to the polyadenylate-binding protein type-1 family.
CC {ECO:0000256|ARBA:ARBA00008557, ECO:0000256|RuleBase:RU362004}.
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DR AlphaFoldDB; A0A3Q3F0S3; -.
DR Ensembl; ENSLBET00000013894.1; ENSLBEP00000013194.1; ENSLBEG00000010084.1.
DR GeneTree; ENSGT00940000157106; -.
DR Proteomes; UP000261660; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12378; RRM1_I_PABPs; 1.
DR CDD; cd12379; RRM2_I_PABPs; 1.
DR CDD; cd12380; RRM3_I_PABPs; 1.
DR CDD; cd12381; RRM4_I_PABPs; 1.
DR Gene3D; 3.30.70.330; -; 4.
DR Gene3D; 1.10.1900.10; c-terminal domain of poly(a) binding protein; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR036053; PABP-dom.
DR InterPro; IPR006515; PABP_1234.
DR InterPro; IPR002004; PABP_HYD.
DR InterPro; IPR034364; PABP_RRM1.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR045305; RRM2_I_PABPs.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR NCBIfam; TIGR01628; PABP-1234; 1.
DR PANTHER; PTHR24012:SF466; POLYADENYLATE-BINDING PROTEIN 1-LIKE; 1.
DR PANTHER; PTHR24012; RNA BINDING PROTEIN; 1.
DR Pfam; PF00658; PABP; 1.
DR Pfam; PF00076; RRM_1; 4.
DR SMART; SM00517; PolyA; 1.
DR SMART; SM00360; RRM; 4.
DR SMART; SM00361; RRM_1; 3.
DR SUPFAM; SSF63570; PABC (PABP) domain; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS51309; PABC; 1.
DR PROSITE; PS50102; RRM; 4.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU362004};
KW Reference proteome {ECO:0000313|Proteomes:UP000261660};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176,
KW ECO:0000256|RuleBase:RU362004}.
FT DOMAIN 11..89
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 99..175
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 191..268
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 294..370
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 542..619
FT /note="PABC"
FT /evidence="ECO:0000259|PROSITE:PS51309"
SQ SEQUENCE 626 AA; 70106 MW; 64BF65E60BCCF9CB CRC64;
MNSTGQSYPL ASLYVGDLHP DVTEAMLYQK FSPAGPIMSI RVCRDIITRR SLGYAYINFQ
QPADAECALD TMNYDVIKGR PIRIMWSQRD PGLRKSGVGN IFIKNMDESI DNKALYDTFS
AFGNILSCKV VCDEKGSKGY GFVHFETHEA ANRAIDTMNG MLLNDRKVFV GHFKSRKERE
VEFGTKAMKF TNVYIKNFGE DYSDEKLKEV FSSFGRTLSV RVMRDERGRS RGFGFVNYAN
HEDAQKAVDE MNGKEINGKT IFAGRAQKRL ERQGELKRKF DQIKQDRIQR YQGVNLYVKN
LDDGIDDERL RKEFAPYGTI TSAKVMTDGS LSKGFGFVCF SSPEEATKAV TEMNGRIVAT
KPLYVALAQR REERKAILTN KYMQRLASLR TMTSPIIDSY HQGGYYMTVP QPPARSFYNH
NAVSNMRPVP RWTGQPPRVQ GPYPAQYAGT SVPRRGSNPI ATVRQASTQA PRIISSSQKT
NNIGTQTVGG RTDVPGVTRS GQYKYSSAVR NVTQVVTIPA PMTRLQVISA PVIEQQVHIQ
GQEPLTASLL AAAQPMDQKQ LLGERLYPLI HSLHPNLAGK ITGMLLEIDN SELLHMLESP
ESLHAKVDEA IAVLQAHQVK DCSPKK
//
