ID   A0A3Q3F5R4_KRYMA        Unreviewed;       488 AA.
AC   A0A3Q3F5R4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 {ECO:0000256|ARBA:ARBA00018240};
OS   Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX   NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000008892.1, ECO:0000313|Proteomes:UP000264800};
RN   [1] {ECO:0000313|Ensembl:ENSKMAP00000008892.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, myofibril, sarcomere
CC       {ECO:0000256|ARBA:ARBA00004204}.
CC   -!- SIMILARITY: Belongs to the class-I pyridine nucleotide-disulfide
CC       oxidoreductase family. PYROXD1 subfamily.
CC       {ECO:0000256|ARBA:ARBA00008147}.
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DR   AlphaFoldDB; A0A3Q3F5R4; -.
DR   Ensembl; ENSKMAT00000009027.1; ENSKMAP00000008892.1; ENSKMAG00000006649.1.
DR   GeneTree; ENSGT00390000014894; -.
DR   OMA; MCENLIL; -.
DR   Proteomes; UP000264800; Unplaced.
DR   GO; GO:0030017; C:sarcomere; IEA:UniProtKB-SubCell.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.30.390.30; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 3.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR   InterPro; IPR041575; Rubredoxin_C.
DR   PANTHER; PTHR43429; PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR43429:SF2; PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF07992; Pyr_redox_2; 2.
DR   Pfam; PF18267; Rubredoxin_C; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000264800}.
FT   DOMAIN          12..167
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
FT   DOMAIN          288..371
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
FT   DOMAIN          401..465
FT                   /note="NADH-rubredoxin oxidoreductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18267"
FT   REGION          222..248
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        225..239
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   488 AA;  53313 MW;  7478C2AAEDF5B20D CRC64;
     TAMAGKQVKK FEFVVVGGGI AGVTCVEQVA SRFPSADVAL ITAGLQIKAV TNYKQVSKTL
     EEFDVEERPS GVLEERFPNL TVIHSAVKSL HTHSHCVETA DGRVFGYKKL CLCSGARPKL
     LTQDDPRVLG IRDTDSAQEF QKRLSKAKRI VVVGNGGIGL ELVYEVEGCE VIWAVKDKAI
     GNAFFDAGAA QFLIPALEAD KPQAAAPCRR LCYTTEEPGP GAAQTFTAGG TSRGRSSGSV
     EPGSALGPDW HREPDLLISS YSPSPGLFFF DFHSFILKSS EGSWPVYIQL TNGKAVGCDF
     VVSATGVVPN TEPFLRGNSF AVADDGGLQV DDHMRTSEPD VYAAGDVCTA CWEHSPLWQQ
     MRLWTQARQM GWHAGRCVAA DVLSEPIELD FCFELFSHVT KFFNHKVVLL GRFNAQGLGS
     DHELLVRCTK GREYVKVVLS RGRMVGAVLI GETDLEETFE NLMLNRMDLT AYGEELLNPD
     VDIEDYFD
//