ID A0A3Q3F6U9_9LABR Unreviewed; 2854 AA.
AC A0A3Q3F6U9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Bromodomain PHD finger transcription factor {ECO:0000313|Ensembl:ENSLBEP00000015646.1};
GN Name=BPTF {ECO:0000313|Ensembl:ENSLBEP00000015646.1};
OS Labrus bergylta (ballan wrasse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrus.
OX NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000015646.1, ECO:0000313|Proteomes:UP000261660};
RN [1] {ECO:0000313|Ensembl:ENSLBEP00000015646.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR Ensembl; ENSLBET00000016577.1; ENSLBEP00000015646.1; ENSLBEG00000012115.1.
DR GeneTree; ENSGT00940000154830; -.
DR Proteomes; UP000261660; Unplaced.
DR GO; GO:0016589; C:NURF complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd05509; Bromo_gcn5_like; 1.
DR CDD; cd15559; PHD1_BPTF; 1.
DR CDD; cd15560; PHD2_3_BPTF; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR038028; BPTF.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR028941; WHIM2_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45975; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR PANTHER; PTHR45975:SF2; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF00628; PHD; 2.
DR Pfam; PF15613; WSD; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00571; DDT; 1.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS01359; ZF_PHD_1; 2.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000261660};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 227..287
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 377..424
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2685..2736
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2762..2832
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 553..768
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1067..1164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1204..1466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1480..1544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1556..1609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1631..1655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1878..1908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1941..1968
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2181..2207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2300..2358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2603..2672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2441..2476
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2531..2558
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 30..44
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..173
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..618
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 680..723
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1085..1130
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1145..1160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1206..1230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1305..1333
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1337..1352
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1363..1377
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1391..1424
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1435..1466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1500..1514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1523..1544
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1556..1576
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2300..2320
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2332..2358
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2622..2645
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2649..2672
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2854 AA; 312668 MW; A2BC0AA77B84D5BA CRC64;
MRGRRGRPPK QAAMMREGSP GPVRGSRGGR SRGMRGRGRG RGRGRGRGAS VGVIGTGSTE
VDTEISGREN FHSSRGRRKV GASSSAAAAV SRGRGGRGRG RGSRGGRGSR GGVRRPQTKV
VYDDNSDEED DNLSYRSDDD ELLNDNPSSD LEEEEALGND SDYLEELPDD EDASYCTESS
FKSHSTLGST PGRRRSRALR PQSPILEAKN IPPLDLPKSS EDLLVLNSQL LNVSAVYEVL
RNFGTVLRLS PFRFEDFCAA LSSQEQCTLL AETHISLLKA ILREEDTSNT TFGPTDVKDS
VNSTLYFVDG MTWPEVVRAY CESDPEYRHI LPCQEGEDYP YEPLESKIKV LQFLVDQFLA
TNIAREELMS EGVVAYDDHC RVCHRLGDLL CCETCSAVYH LECVKPPLQE VPEDEWQCEV
CVAHKVPGVA DCIPEVQRSK PFIRQLPVGY DRHHRKYWFL NRRIVVEEDG EQEDKAIWYY
STKVQLAELI DCLDKEYWEA DLNAALEEIR DEVHAHMDIS EDLTNKARGS NRCYLTAANE
EILDRLRAKK EEELEEVKRR AAEEARLERE KKELEAERER ENEEVKVKEE VQQDGKELRK
EEETKDSGWE EKSGRIKTEV VEAPSTGHEG SGGCSVSEGP LPAAPAPTQT TPSTDSYRPA
PEVPKPKVST LKALIGGGSH TEVSNCTKET PPSDSVPPGG NGIPSLSQPS QTSEENSNSS
VGAAVPPRGP EPPDLADKSS QSSLASFDDT GDCKDSANGD TPGLGGKKSA ATRMVTRLRN
PESKLSQLKN QQVIVVNAQG DITRVSTRSS KDVVMKGTLS QFFKLGQEGK YRVYHNQFSS
NTVALNKHQH REDHDKRRHL SHKFCMTPAG EFKWNGSIYG SKVLTISTLR LTIIQLENNV
PAPFMHPNWA SHRTNWIKAV QMCSKAREFA LALAILECAI KPVAMLPVWK DSLGHTRLNR
MTSMEREEKE KVKKREKKLE DEETLQQATW VKYTFPIKHQ VWKQKGEEYR VTGYGGWSWI
SRTYVQRFLP RLPGNTNANY RKELEDAKLG KKCTLLDLSR RPSVAAAEAQ EVTVPSSEAK
VEESSNLSEP AKDRLTSIED LKSGERNEEE TKDGTVVKEK SAHESPEKME VDPTPPPSYE
EPRSSIEEAS MKEEPADEPS RPFNYDVVDV SKGFLTRIAY KKKVKSSKLD ILLERRVKQH
VIEERQRQQV SASNPMTSTS ASSTPTPALS TPVRPRSPLR PHNLTQKQLA LGEAVKVTEK
PSITQTPEPG DGGERLVGGG EGQSELSKTA DEKVTPPPPS PALGSTPTDS SSTGTGEHSV
SPQTTSTPQG LEADLVERTT GPKEKNSDIS GKEGVKLPDV QETNTGGILS SAEVSSDDTK
AAHIENTRLK MDSVRTSTSV LDQKNSQNTS PSKLTQQEAL SSVHSEENGM GPEESQGIKQ
GQTDAVSTPE PASPLPQVNG NDAIGSELSN SVVSANNGVL TNSSQLKVNN VGKGEEQGLG
VSLNDSTQQK PLVNGDVARV NDFTEVGTKE SKSTASDEDY KPPPKVLRLE NNIDALGGNT
QSTKQHDSTS PTKPSSGVKI IRMAPSPIPS AEESSLSDDF AEENSNSGTA ETIVTQVTTT
ATTTTTVVST QTRTTTKVSP AVPGETGTTE SSAVSTLTTM TKTTVTKICS SDGQSDDSQS
EIVTQEDKLL ASVRKSTTNI RGETSVSLED YSSTKGRVRL LKFSRTKKTR SDTALPSYRK
FVTKSNRKSI FVLPHDDVKV LGRRGGLREV PIFSYNAKPA LDIWPYPSPR PTFGITWRYR
LQTVKSLAGV SLMLRLLWAS LRWDDMAVKP SAAVGTTRTE TSDTEITTTE IIKRRDVGPY
GIRSEYCIRK IICPLGVPET PKETHTPQRK GLRSSALRPK KPEPAKQTGP VVLETWVAEE
ELDLWEIRAF SERVEKEKAQ AAEQAKKRLE QKPGSVNATP TGIPSTPAAT PKVIVGSLSG
QGTPTTKVVL STKMGTPVTF QQNKNFQQSF ATWVKQGQST GAGNETTVAT SGGHTFQITG
TSVGGKVVTT KLPLPANSKI VTVNVPTSQG GVVQQKVLGI IPSSTAGGAQ TYTTFQPRTT
TLNIRPNTPG SQQQVLAAGT QIRPGMTVIR TPIQQTGPMG KTILRTPLVV QQGQGGQQVV
TQIIRGQAVS TAISGASPVA TVTGQGSASP TTGGQAAGQT TQGTPRAQAQ GQVKLSLAQI
TQLTQKQQAA SGVERQAGAG GTQQALTVMV QGQGQTAGQL QVIPQGVTVI PGPGQQLMQA
SLPNGQVQRF LFTPLASAAT PTSSTATQPN CASTKAPAQP AQQAAAPIQA GATPLATTST
PSSATPQGQL PPQTQAHMPI QSPTSLQVKT QGGTAQLQIQ QSPQIISMSG LQQQVLAQLQ
AQQAAGSLPQ HIKLQLPIQI QQTGTTSAQG GQIGNVVTIQ TASVQEQLQR IQQLREQQQQ
KKRQAAEAKR EQALNAASQS DIIQKQVVMK QNAAIEHLKQ KKTMTPAERE ENQRMIVCNQ
VMKFILDRID KDERQETKRR KKEEVVEAKR RLANASKLSS LLYRHKESLK MEILKKRALL
DKELQLEAQE ELKRDLLRMR REKERAQAAA QQAAQAAAAA AAASARNQQQ HSHTHAISSQ
HHATTAASTH KRKREEERET ATPAKSKKKK MILTTSTKES KKDIKLYCVC KTPYDETKFY
IGCDRCQNWY HGRCVGILQS EANHIDEYVC PQCQSTEDAM TVFTPLTDKD YEGLRRTLRS
LQAHKMAWPF LEPVDTNDAP DYYRVIKEPM DLSTMEERLQ KREYVKLTEF VADMTKIFDN
CRYYNPSDSP FYQCAEVLET FFVQKLKGFK ASRL
//
