ID A0A3Q3F8V8_9LABR Unreviewed; 1176 AA.
AC A0A3Q3F8V8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Neurofascin-like {ECO:0000313|Ensembl:ENSLBEP00000016019.1};
GN Name=NFASC {ECO:0000313|Ensembl:ENSLBEP00000016019.1};
OS Labrus bergylta (ballan wrasse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrus.
OX NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000016019.1, ECO:0000313|Proteomes:UP000261660};
RN [1] {ECO:0000313|Ensembl:ENSLBEP00000016019.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily.
CC L1/neurofascin/NgCAM family. {ECO:0000256|ARBA:ARBA00008588}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3Q3F8V8; -.
DR Ensembl; ENSLBET00000016955.1; ENSLBEP00000016019.1; ENSLBEG00000012107.1.
DR GeneTree; ENSGT00940000157024; -.
DR Proteomes; UP000261660; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 4.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR026966; Neurofascin/L1/NrCAM_C.
DR PANTHER; PTHR44170:SF12; NEUROFASCIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF13882; Bravo_FIGEY; 1.
DR Pfam; PF00041; fn3; 4.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 4.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 4.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261660};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1045..1066
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 38..130
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 248..342
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 347..434
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 440..526
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 530..613
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 624..720
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 722..815
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 820..908
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 912..1005
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 1176 AA; 133933 MW; FDC5067E1226D7B9 CRC64;
MFIFFWPWCS CALCYLCSNF TFSKLMYSIS LPAVRQPPTI IKQSMKDHIV DPKDTMVIEC
EAKGNPHPIF SWRRNGKYFN VARDPQASVR RRSGTLDIYA WNNPEQYEAE YQCIASNEYG
SAYSNKIRLR LYRAPVWPRE ILEPVVVSVG LPLVLSCDPP PGPPFNWPIQ TAFPTMQPVR
PDRRVSMGVN GDLYFSNVLF NDSDSDYCCN ARFPYKNVIQ QKMPVVVKVL TSKYDYTTAV
RSSFVYLPYF AAPTWLSPTG SSSSILVLQG EELLLECIAA GVPTPRITWT KDGEDLVVTP
RMKVKNFNKM IQIPKADFDD IGEYVCTATN KIGYIEHTIM VKVKAAPFWL EKPTDLVLAP
EENGHLVCRS DGIPRPTISW FINGEPIETS TPQPNRQVSG DTLILRGVTA ANNAVYQCNA
SNQYGYLLAN AFVNVLHATP RIIGPRNELI KVIEGSHTFL DCRYFGSPVP DLRWSKYGQG
NLEGNRFNTH SNGTLEIRHI RIEDQGTYLC IVSNLAGRDE SQIRVEVKEP TLIVTRPQSM
KVIRGTDVRF ECGVKADLTT PVTTSWMKDK RMVTYGWRIS LDESNLVITN VNRGDEGNYT
CIIKSELDQK SASARLMVMD RPEPPTNLEL SDPYERSVRL SWIPGASNHN PVTEYLVQYD
DDDWLPGKWR NLSTYPGNLN SVILHLTPFT YYEFRVIAIN EIGMSRPSRP SKRFQSSAPD
VIPKNLKGVG TWRNNMEISW EPLTYREWNG PHLKYLVWWK RRDSREEWKN ATTKWLKYYI
YDADTFTPYD IKVQAVNDFG LGPESPVVTG YSGEDRPVTA PLNLRVSDIE STQVTVHWDP
VKRNSMMGEL KEYKVTMKSK SFPENGPEPS GVLTGIIPYS NYKMYIVVTN NRYEGPPSNY
IHFSTPEGVP SAPKSFRIQQ RHLDSIYVDW ELPAEPNGVV TGYSLKYQTG TGEELRVEDF
PPNVTSFSMR RYDRYTRYRF SVAARTRLGI GEWHTEESPH YTTESNFIIN QSIDLDSVWT
KRCAHVLVCI SAYATDQVDI TTQGWFIGIM CAVALIVLIL LIVCFIKRSR GGKYPVRDKK
DISLEPMDDK DQEGSFDYRE EERGLQRGQT SIESIMKRSD SDDSLVDYGE GGEIQFNEDG
SFIGQYTGTR RDVREVDFGV GSVELHSPMN AIYSLA
//
