ID A0A3Q3FA48_9LABR Unreviewed; 553 AA.
AC A0A3Q3FA48;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Interleukin-1 receptor type 1-like {ECO:0000313|Ensembl:ENSLBEP00000016474.1};
OS Labrus bergylta (ballan wrasse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrus.
OX NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000016474.1, ECO:0000313|Proteomes:UP000261660};
RN [1] {ECO:0000313|Ensembl:ENSLBEP00000016474.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the interleukin-1 receptor family.
CC {ECO:0000256|ARBA:ARBA00009752}.
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DR AlphaFoldDB; A0A3Q3FA48; -.
DR STRING; 56723.ENSLBEP00000016474; -.
DR Ensembl; ENSLBET00000017416.1; ENSLBEP00000016474.1; ENSLBEG00000012729.1.
DR GeneTree; ENSGT01090000259985; -.
DR InParanoid; A0A3Q3FA48; -.
DR Proteomes; UP000261660; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR015621; IL-1_rcpt_fam.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11890; INTERLEUKIN-1 RECEPTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11890:SF26; INTERLEUKIN-1 RECEPTOR TYPE 1; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR01537; INTRLKN1R1F.
DR SMART; SM00409; IG; 3.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS50104; TIR; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius}; NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000261660};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..553
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018629103"
FT TRANSMEM 332..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 222..322
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 375..539
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 553 AA; 62345 MW; 68677B2253A7FD68 CRC64;
MDSSRLLFSV FFLLITTSDC SDTDELQCND MDNEIFHRLE GEAFYFLPYV LMDGNIPDEN
ITWHKNNSEE ISNNEDRMVH YHGGALFFLN LQIEDSGFYT ALHRTSSGEC FNYHLNLVVF
DKSHANTEVL FRTVSGGSKN RKIPCPDNVK ETCSVFRGKL SWEKDSNIFP DEHGAQLWIM
DVDKSQEGIY TCVCTWKHHE KEYKTSGSRK LEVEDQVVVK PPKILSPANK EQFADEGLEI
KLNCSVLCGK NVGNDCQATW RIDGSPISQI DGYNLTTKRE EPADGTTVTA ILTIKRVSAK
DFLAEFTCTG HGGFEPASAT LTLKPKESKT PLIIGALSVL FFCVFAAVLI KYFAIDLALL
FRPYFTLALN NKDGRVFDAY VVYQTQNLDN PSEDTFSLFV TKNLPSVLEE KCGYRLFIQG
RDDIPGEDRL ELVEDRMNQS RRLMVILTPG SGSESSPTSP QNSVIGGFDW QVGLHHALVQ
REMNVILIQL GDMGPEGYAH LPPGLQHLIH KSAPIKWPED SRGASAYNSR FWKRVRYLMP
VTPAKKDCQS LII
//
