ID A0A3Q3FAW1_KRYMA Unreviewed; 392 AA.
AC A0A3Q3FAW1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=REST corepressor 1 {ECO:0000313|Ensembl:ENSKMAP00000010512.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000010512.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000010512.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CoREST family.
CC {ECO:0000256|ARBA:ARBA00038011}.
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DR STRING; 37003.ENSKMAP00000010512; -.
DR Ensembl; ENSKMAT00000010674.1; ENSKMAP00000010512.1; ENSKMAG00000007876.1.
DR GeneTree; ENSGT00940000155654; -.
DR OMA; TSTISCW; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd00167; SANT; 1.
DR Gene3D; 1.20.58.1880; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR000949; ELM2_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR049048; REST_helical.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR PANTHER; PTHR16089:SF11; REST COREPRESSOR 1; 1.
DR PANTHER; PTHR16089; REST COREPRESSOR COREST PROTEIN-RELATED; 1.
DR Pfam; PF01448; ELM2; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR Pfam; PF20878; REST_helical; 1.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51156; ELM2; 1.
DR PROSITE; PS51293; SANT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800}.
FT DOMAIN 53..126
FT /note="ELM2"
FT /evidence="ECO:0000259|PROSITE:PS51156"
FT DOMAIN 276..327
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 337..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 392 AA; 44683 MW; C48BDAEA69C239DC CRC64;
MLERNPEAPG KRRGPGTAAG SGGKSLSGNG TSANSCWEEG SSGFSSDEEH GGGGMRVGPQ
YQAVVPDFDP DVAQAAQLRD NLGMLPVSPI CRLSLTVFPF LRQALGMLFW HKHNIEKSLA
DLPNFTPFPD EWTVEDRVLF EQAFSFHGKS FHRIQQMVSL KNACKKKNYL YSCFLKLRTK
ESEDKYKKYK NKLVFIIRQH KKKYYSDLLN RSNGDMRATW KVMNGVLKNH KRXRQLDCQL
VSIKKQNQTI KQTNSLLKEQ LSSGVEEFKQ PEMSQKFNNR WTTEEQLLAV QAIRKYGRDF
QAISDVIGNK SVVQVKNFLV NYRRRFNLDE VLQEWEAEQE MEGGGGGGDA GEKENEEEEE
KIMEVCSAED EGAASEQRVK VRWTFRLSFG SK
//
