ID   A0A3Q3FRA4_9LABR        Unreviewed;       818 AA.
AC   A0A3Q3FRA4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Interferon-induced GTP-binding protein Mx {ECO:0000256|ARBA:ARBA00015210};
DE            EC=3.6.5.5 {ECO:0000256|ARBA:ARBA00011980};
DE   AltName: Full=Interferon-inducible Mx protein {ECO:0000256|ARBA:ARBA00031810};
OS   Labrus bergylta (ballan wrasse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Labriformes; Labridae; Labrus.
OX   NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000021448.1, ECO:0000313|Proteomes:UP000261660};
RN   [1] {ECO:0000313|Ensembl:ENSLBEP00000021448.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC       superfamily. Dynamin/Fzo/YdjA family. {ECO:0000256|RuleBase:RU003932}.
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DR   AlphaFoldDB; A0A3Q3FRA4; -.
DR   STRING; 56723.ENSLBEP00000021448; -.
DR   Ensembl; ENSLBET00000022600.1; ENSLBEP00000021448.1; ENSLBEG00000016445.1.
DR   GeneTree; ENSGT00940000155214; -.
DR   InParanoid; A0A3Q3FRA4; -.
DR   Proteomes; UP000261660; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   CDD; cd08771; DLP_1; 1.
DR   CDD; cd01256; PH_dynamin; 1.
DR   Gene3D; 1.20.120.1240; Dynamin, middle domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR022812; Dynamin.
DR   InterPro; IPR001401; Dynamin_GTPase.
DR   InterPro; IPR019762; Dynamin_GTPase_CS.
DR   InterPro; IPR045063; Dynamin_N.
DR   InterPro; IPR000375; Dynamin_stalk.
DR   InterPro; IPR030381; G_DYNAMIN_dom.
DR   InterPro; IPR003130; GED.
DR   InterPro; IPR020850; GED_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR11566; DYNAMIN; 1.
DR   PANTHER; PTHR11566:SF32; DYNAMIN-1; 1.
DR   Pfam; PF01031; Dynamin_M; 1.
DR   Pfam; PF00350; Dynamin_N; 1.
DR   Pfam; PF02212; GED; 1.
DR   Pfam; PF00169; PH; 1.
DR   PRINTS; PR00195; DYNAMIN.
DR   SMART; SM00053; DYNc; 1.
DR   SMART; SM00302; GED; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS00410; G_DYNAMIN_1; 1.
DR   PROSITE; PS51718; G_DYNAMIN_2; 1.
DR   PROSITE; PS51388; GED; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003932};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW   Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU003932};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261660}.
FT   DOMAIN          28..294
FT                   /note="Dynamin-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51718"
FT   DOMAIN          515..621
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          650..741
FT                   /note="GED"
FT                   /evidence="ECO:0000259|PROSITE:PS51388"
FT   REGION          742..818
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        771..818
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   818 AA;  92120 MW;  8ED3E75D9D92864E CRC64;
     MGNRGMEDLI PLVNRLQDAF ASIGQNSSLD LPQIAVVGGQ SAGKSSVLEN FVGKDFLPRG
     SGIVTRRPLV LQLINCPTEY AEFLHCKGKK FIDFDEVRQE IEAETDRVTG ANKGISPVPI
     NLRVYSPHVL NLTLVDLPGM TKVPVGDQPA DIEHQIREML MQFVTKDNCL LLAVSPANSD
     LANSDALKIA KEVDPQGLRT IGVITKLDLM DEGTDARDIL ENKLLPLRRG YIGVVNRSQK
     DIDGRKDITA ALQAERKFFL SHPSYRHLAD RMGTAHLQKA LNQQLTNHIR ETLPALRSKL
     QGQLLAIEKE VEEYKNFRPD DPGRKTKALL QMVQQFAVDF EKRIEGSGDQ VDTYELSGGA
     KINRIFHERF PFELVKLESD EKTLRKEISY AIKNIHGIRT GLFTPDMAFE TIVKRLIAQI
     KEPCQKCVDM VINELVNTVR QCTQKLAQYP MLREEMERIV TQHIRDRESR TKDQVMLMID
     IELSYINTNH DDFIGFANAQ QKSNQASKKK AAGNQVIRKG WLTINNIGIM KGGAKDYWFV
     LTAETLSWYK DDEEKEKKYM LPVDNLKFKD IEKSFMSSKH IFALFSTEHR NVYKDYRQLE
     LASDSQEEVD SWKASFLRAG VYPERSVSEA EESSGDGQIH SMDPQLERQV EIVRNLVDSY
     LSIIHRTVRD LIPKAIMHLM VNNTKEFIHA DLLAQLYSCG DQNSLMEESQ DQAMHRDDML
     KMYHALREGL SIIGDISTST ITTTMPPPVD DSWLQVTGMP SGRRSPMSSP TPQRRAPPGP
     PRPGGRAAPS RPAVSPDPGP APSVPSRPNR APPPGVPR
//