ID A0A3Q3FSJ9_KRYMA Unreviewed; 2364 AA.
AC A0A3Q3FSJ9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=NBAS subunit of NRZ tethering complex {ECO:0000313|Ensembl:ENSKMAP00000015532.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000015532.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000015532.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_017282847.1; XM_017427358.1.
DR STRING; 37003.ENSKMAP00000015532; -.
DR Ensembl; ENSKMAT00000015756.1; ENSKMAP00000015532.1; ENSKMAG00000011503.1.
DR GeneID; 108242493; -.
DR KEGG; kmr:108242493; -.
DR CTD; 51594; -.
DR GeneTree; ENSGT00390000012474; -.
DR OMA; KHMLPAE; -.
DR OrthoDB; 7541at2759; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0048703; P:embryonic viscerocranium morphogenesis; IEA:Ensembl.
DR GO; GO:2000623; P:negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:Ensembl.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR029145; NBAS_N.
DR InterPro; IPR013244; Sec39_domain.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR15922:SF2; NBAS SUBUNIT OF NRZ TETHERING COMPLEX; 1.
DR PANTHER; PTHR15922; NEUROBLASTOMA-AMPLIFIED SEQUENCE; 1.
DR Pfam; PF15492; Nbas_N; 1.
DR Pfam; PF08314; Sec39; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 4: Predicted;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 81..361
FT /note="Neuroblastoma-amplified sequence N-terminal"
FT /evidence="ECO:0000259|Pfam:PF15492"
FT DOMAIN 720..1359
FT /note="Sec39"
FT /evidence="ECO:0000259|Pfam:PF08314"
FT REGION 452..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..471
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2364 AA; 265698 MW; A528E18FCAC93F01 CRC64;
MAEGSLVEGE DENILYDLLV INEWPPETDT QLRGSKEPNS SLIAKAVTGP FRLLLHNLWY
SPSRSSLPLG LIRLANKQIS WQLALSSHGK LLAVVQDQYV EIRSVRDDFG SVIVKCQVPK
DPNPQWRRVA WSYDCTLLAY ADSTGTVRLF NLKGSELFVI PPVGSFPSDF SHAVAGLIFL
EYTASAQWSA ELLVITHGGG LKSYLVSVGT NQNFQENHAF SFSPQHSHGV TSAIYLPAHR
LLLIGGCESG ADGASKASCS GITAWRALSS SPHYKQVTSY EDDISPKQKR GFLRMPSFRW
FSRQGDEKDG VFRMSLSPDG TLLAVIHFSG RLSLWDVPSL KQRATWSQEE QPGFEEINPE
WRTSLERRKK IKDKEQYYPL VDVSWWSDGV LILARCSGSV TVSSVRTLRN LLGKSCEWFE
PSPRVTAAHD GGFLSLECEV RLAQKRVRLE SNLSGGASED EEGDDGDSDI DEESSAKARY
FGYAKQGLYY VTEMERFAPP RKRPRTVIKN YRLVSLRSTT PEELYQRKID NEEYGEALSL
AQAYNLDSDL VYQRQWRKSP VSIASIQDYL SKIRKRSWVL HECVERVPEN VDAAKELLEY
GLKGTDLEAL LAIGHNEDGG RFIMPGDVDL DDLPYEDVLL GDEELEMTKE KETKKRQELL
AKVDFRRLTL EQKELCRSRL KLLSYLDRLA TYEEILGGPH AAEQKYDAEF FKTFRSQNIV
LSARNYARES NVQALDILFT YHGGELLQHR LAILYNFPET TSPHEYSTLL PEARLDDRGE
LVLIPWVEQR HREMDWCESE ECRAVLEQNL LDDDDFLYEE ASELRRFRTT TPSIELLTDW
YQSRAQDIDS CSRQLDCALS LVRLGKERKI PGLELLCDDL VTMETLVYES SCELNVTLKD
LQQLSDIDKL CLLMKNSSSE RYVKDAFQWM VPFLHRCEGQ KGGAAKSLLA KYLVGLAQQD
LTLPLVIFQH SKPNCQQRII GDPDQLMEVA LECIYSCERD DQLSLCYDIL ECLPQRGFGP
KTDITASLHD QVDKLEKHLS VVEVLEKHGL KKPILYVKNS QSSEEEAHQL MVKLCRHTGR
KNPPVGEAVW RGLLEDLLNM QQNAYTCLKP ETCHQVFVES LLCSSRVENI RLAGQFMHCS
KVGQDVPVSL SFRGKGYTLK VAYNNSVELV LAAAREYFNS STALTDPCMN LARACLQLIT
DCPPAVQEEL DLVSALSQLE DFGVCILPLQ VRLRSDRLSL IEECVSHCST AYKQSTTLLD
LASLLRVSGD DEAKRRGQVL TLLAEQSLRF LDFKASYIHC QDLMAAGYSP AWDVCSLLGQ
CEGYADLEAR QELLAFALTH CPPDSIHALL AASSDLQTQV LYQAVNYQME PVIPEAEQEA
STSTVASPVG TAGDLLHRTT AKTMKVLTTT GVTTKAVLSA VSDHRWWKES LSYLRPLHGH
DAGATTQEGV CENSNLEHQG CSPFYQELIE DPYVDPSQDV YSSYREMPKE NFAEVLLRTG
KLAEAKTAGE TLFPATEVLL QLANDAFPRD MMLALSYLLA LPQVLDANRC FEKQCRSALS
LQLAAYYYSL QIYSHLLPCF KDKNHTLYQA DPKELIRLVT QHVSSYSDWP EELQKLISQL
HVYNERLTDF TQAQVLQGLG RGVDVQRFST DSDYKKETIL GLTETLDDDV YRIALSLAKR
YNVLLWEVYM THLEFLFTDS GLSTKDIEAR SDFLKLFETL KGDPEAFYSH MTKYVLPTIE
GTDLGRLLYY YTLIDAAGCE PYVTTAIKPD SHVKLLKKLR AVANGVNYKK LTDESSDPLA
SLQPVLTSQN VLSISKLASR LSLPGGGGAT VSPSSVHAVW LQKLFWKGDP QLLKRPPQSD
QDYLHAYDTC AKYLDRLAPA DTVPFLDSIT FSPDAAKNLS VQARLELIRR ATKALRQLGE
KSRKRGGDVC GEQEGTDAAG TTFDEALAHL QQSQAHLDTL SHEFILSLRD SQQEQLQRYS
QLYDLSRSER PKICELAVTM ATDGQPLAQI KELLTVAVGP LDLTVKTVLW EAVKRVVAAL
SGDVGAMTNC PQPLGVLEAV VTSVHNNVQS GDSAVTSDDL LAWLRPFCGD ASLPVRPRID
VLQILESNFP LRDSDVRLLL LYRTQAVLKD REVQVEDVED EDKRYDLFRE LLNAAQKWED
FQLLMLLLQA WPPMMKEEVA KSEGNPWVML TSMLLTRCQE SEVRLDLGQQ VVTMVRSLYN
TKHKLPVQCV RHVAHLLLHN QPSLLQPALK LMCESEDEQL LQLTLDQINN MSIETASSCD
AELLSLLLDA GLLVGCVSST LYPLLSSHML SHQQEGGWDV EKAAAELMAA GHGPEAGSLL
LAHRGTHRAQ FTFNSALAVL RKWL
//
