ID   A0A3Q3G101_KRYMA        Unreviewed;      1196 AA.
AC   A0A3Q3G101;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Plakophilin 4 {ECO:0000313|Ensembl:ENSKMAP00000018102.1};
GN   Name=PKP4 {ECO:0000313|Ensembl:ENSKMAP00000018102.1};
OS   Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX   NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000018102.1, ECO:0000313|Proteomes:UP000264800};
RN   [1] {ECO:0000313|Ensembl:ENSKMAP00000018102.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the beta-catenin family.
CC       {ECO:0000256|ARBA:ARBA00005462}.
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DR   RefSeq; XP_017279980.1; XM_017424491.1.
DR   AlphaFoldDB; A0A3Q3G101; -.
DR   STRING; 37003.ENSKMAP00000018102; -.
DR   Ensembl; ENSKMAT00000018354.1; ENSKMAP00000018102.1; ENSKMAG00000013437.1.
DR   GeneTree; ENSGT00940000155773; -.
DR   Proteomes; UP000264800; Unplaced.
DR   GO; GO:0098609; P:cell-cell adhesion; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR028435; Plakophilin/d_Catenin.
DR   PANTHER; PTHR10372:SF8; PLAKOPHILIN-4; 1.
DR   PANTHER; PTHR10372; PLAKOPHILLIN-RELATED; 1.
DR   Pfam; PF00514; Arm; 3.
DR   SMART; SM00185; ARM; 6.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 3.
PE   3: Inferred from homology;
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264800}.
FT   REPEAT          577..604
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REPEAT          621..664
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REPEAT          879..916
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REGION          71..162
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          192..241
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          266..346
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1034..1054
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1089..1115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          33..60
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        75..162
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        192..211
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        221..241
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1089..1104
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1196 AA;  131866 MW;  68F2EF366D350F6B CRC64;
     MPAPEQSPVT EEGLLLTICN SSTGRKMETD STANNILASV KEQELQFERL TRELEVERQI
     VANQLERCRL GAESPGAGSS SSSEKSLPWR TADTSASGDT KSRVTDSSQS PSYRIRTESE
     QVSLYSPEQS SLHERSAGNS CGSAQMNSYS DSGYQDASSG YLSGQNHAKA ELKMQHSFPG
     AGTGTLGRNA RAEGQASAQV PTVTTTQPGR AMRRVCSVPS RSHSPAYSTS MSPSRGSLRT
     SVGSAYGSPI VTEPKPYSSI FSTTLPSVQR TSSVGGGTSP YSTQKNSPAG LRRVSSTNSR
     SGTASRTTAS YQTSAGSSSG RMGSPLTMVD NINPPLTKQP AHSSSPIRAS MTAVPQHYSS
     TLPRSMLHNT DPYGPQSYDI YERMTRPDSL ADALIDGDIK GIRSSYASQH SQLGQDVRSA
     ISPDRHIAPI YEDRTFQGPL YRSPSHTQQG TLYRSASGVG SLKRTSSQRS AMTYQRNNYA
     LNTAATYADP YRTAQYRPPE VTYARQPLLM DDDATRSPSI DSIQKDPREF AWRDPELGEV
     IQMLQHHFPS VQANAAAYLQ HLCFGDNRVK SEVGRLGGIK HLVDLLDHKI VEVQRNSCGA
     LRNLVYGKAM DDNKVAVRNA GGIPALLRLL RKTVDAEVRE LVTGVLWNLS SCDAVKMTII
     RDALSTLTNT VIIPHSGWSS STFDDDHKLK FHSSLVLRNT TGCLRNLSSA GEEARKQMRT
     CEGLVDSLLY VIKACVSTSD FDSKIVENCI CTLRNLSYRL ELEMMPSRLM GGHELDGFLG
     RESPSKEVDS SCWGRKKKKK KNSLQEDSWD GVGPIPGFSK SPKGAEMLWH PSVVKPYLTL
     LAESSNPATL EGSAGSLQNL SAGNWKFAAY IRAAVRKEKG LPILVELLRM DNDRVVCSVA
     TALRNMALDI RNKELIGKYA MRDLVNRLPG GNTSLLSDET VAAICCTLHE VTSKNMENAK
     ALADTGGIEK LVNITKGRGD RYSMKVVKAA AQVLNTLWQY RDLRTIYKKD GWNQNHFITP
     VSTLERDRFK SQPTLPTSTI QMSPVSHPAT SATSSPAMLG IKEHRDTIRD YQRPQSTMQF
     YNYQGDGSIH RKQYTGSGKP SPYYYSSPTR EEPRRTQPVY YTDEPSRRNY DTYRMYLQHP
     HGYNDTFLEE VITYPPTVDY QPHGLKSTAN YVDYYTSTRG PLYRSEQYPG SPDSWV
//