ID   A0A3Q3G2P3_9LABR        Unreviewed;      1273 AA.
AC   A0A3Q3G2P3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=DENN domain containing 4C {ECO:0000313|Ensembl:ENSLBEP00000027356.1};
GN   Name=DENND4C {ECO:0000313|Ensembl:ENSLBEP00000027356.1};
OS   Labrus bergylta (ballan wrasse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Labriformes; Labridae; Labrus.
OX   NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000027356.1, ECO:0000313|Proteomes:UP000261660};
RN   [1] {ECO:0000313|Ensembl:ENSLBEP00000027356.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q3G2P3; -.
DR   Ensembl; ENSLBET00000028664.1; ENSLBEP00000027356.1; ENSLBEG00000020364.1.
DR   GeneTree; ENSGT00940000158215; -.
DR   Proteomes; UP000261660; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.100.10.50; -; 1.
DR   Gene3D; 3.40.50.11500; -; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR001194; cDENN_dom.
DR   InterPro; IPR005112; dDENN_dom.
DR   InterPro; IPR043153; DENN_C.
DR   InterPro; IPR023341; MABP.
DR   InterPro; IPR002885; Pentatricopeptide_rpt.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR037516; Tripartite_DENN.
DR   InterPro; IPR005113; uDENN_dom.
DR   PANTHER; PTHR12296; DENN DOMAIN-CONTAINING PROTEIN 4; 1.
DR   PANTHER; PTHR12296:SF17; DENN DOMAIN-CONTAINING PROTEIN 4C; 1.
DR   Pfam; PF03455; dDENN; 1.
DR   Pfam; PF02141; DENN; 1.
DR   Pfam; PF03456; uDENN; 1.
DR   SMART; SM00801; dDENN; 1.
DR   SMART; SM00799; DENN; 1.
DR   SMART; SM00800; uDENN; 1.
DR   PROSITE; PS50211; DENN; 1.
DR   PROSITE; PS51498; MABP; 1.
DR   PROSITE; PS51375; PPR; 1.
PE   4: Predicted;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261660}.
FT   DOMAIN          38..185
FT                   /note="MABP"
FT                   /evidence="ECO:0000259|PROSITE:PS51498"
FT   DOMAIN          177..610
FT                   /note="UDENN"
FT                   /evidence="ECO:0000259|PROSITE:PS50211"
FT   REPEAT          773..807
FT                   /note="PPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT   REGION          904..972
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        937..972
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1273 AA;  142406 MW;  D7F8D664513946B7 CRC64;
     MIEDKGHRVT DYFVVAGLTD KSTPLEQDLS ETKSGGPKAP ITDLAVINRS AGETVPEGFT
     CIDSTYSGQP ANLNHGSLKS PELFLCYKRS RGKSPLIDIG VLYEGKERLI QGCEVIQATP
     YGRCANVNNS SAPPVQPQNS LAVTDICVIV TSKGEIPPHT FCKVEKNLNC GMWGSSVFLC
     YKKSVSASNS ISYKAGLIFR YPEENYESFP LPEPVPLFCL PMGAKIECWA PNTRDPLPVF
     STFVLTLSSG EKVYGSAIQF YEPYPVDLLS EKQKIQLGLL TTVEKKMIPN RPVNTNKCIC
     LLSHWPFFES FRKFLMFLYK LSVSGPHPLP IENIVFFPPS CPMSPLLSLC SLPNLIIISF
     SLSLSLPVSG ADYGTLLMNL GSENCATLLH FVLLENKILL HSLRPAVLTG VAEAVVAMIF
     PFQWQCPYIP LCPLSLAQVL NAPFPFIVGV DSRYFDLYDP PPDVVCVDLD TNTIYLSDEK
     RHNNWKNLPK KPCKSLVNSL SNLHHQLATG TNTTFADFTW HKKKTALEME IQETFLRFMA
     SILKGYRSYL KPITEAPSEK ATAADSLYDL QGFLKSRDRT HQKFYSQLTK TQIFIRFIEE
     CTFVSDKDTG LAFFDDCVEK VEGESSEDTR LLELDESQKS EHTVFVMPPE PAADDGPEPA
     PRYTFPRLHM GLFDRPKELR PAISSRTAGA SLSSSPALLA KRTKQEIKLA YKMAKRFYSN
     PAQWARCLFS HCYSLWFICL PAAAGLAKSK SRAMQQAYNI LLKMRTTEVE VLDEVCFRVV
     MQLCGVYGLP VMAVRVLVEM KKAGVRPNAI TYGYYNKAVL EGPWPSRNRS GLFMWTKLRN
     VLRGATQFKQ ALHSTSSKKG ATLSTTGWYG VCSMVYIYSL FRFPPLFSHL LETMSPGRSC
     IRRRAQGDST DAPQPKPPLE RRSSLPVPPV KTLTGSPGDT PKRSPNTVTR SKTFAVKTRT
     PASTTGSPGP RSASLTALVL MSSCSQCHSC EALVYDEEIM AGWTADDSNL NTNCPFCRTA
     FLPFLHVEFH DLRTMTGYGS VVFEFSDPLG LLEHQAAGKQ QKCSGTSLTR SNSPVSVPYL
     SPLVLRKELE TLLENEGDQV KHSHFLSQHP IIFWNLVWYF RRLDLPSHLP GLILTSEHCN
     KGVQDSKQVY IQLLWDNVNL HQENGDPLYL LWRTFSENSK SLAVKDSNVH ILNANLNVSY
     VSCISCRSIY RDILFLSLVA LGRENIDVEA FDREYRLAYD ELSAEQLKSL HRIDQPPSPS
     VQWCVKCFGA PFI
//