ID A0A3Q3G609_9LABR Unreviewed; 432 AA.
AC A0A3Q3G609;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Tumor necrosis factor receptor superfamily member 16-like {ECO:0000313|Ensembl:ENSLBEP00000028267.1};
OS Labrus bergylta (ballan wrasse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrus.
OX NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000028267.1, ECO:0000313|Proteomes:UP000261660};
RN [1] {ECO:0000313|Ensembl:ENSLBEP00000028267.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR AlphaFoldDB; A0A3Q3G609; -.
DR STRING; 56723.ENSLBEP00000028267; -.
DR Ensembl; ENSLBET00000029608.1; ENSLBEP00000028267.1; ENSLBEG00000021441.1.
DR GeneTree; ENSGT00730000110974; -.
DR InParanoid; A0A3Q3G609; -.
DR OrthoDB; 4222274at2759; -.
DR Proteomes; UP000261660; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR GO; GO:0048922; P:posterior lateral line neuromast deposition; IEA:Ensembl.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd08311; Death_p75NR; 1.
DR CDD; cd13416; TNFRSF16; 1.
DR Gene3D; 6.10.250.1780; -; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 3.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR041448; TNFR16_TM.
DR InterPro; IPR022325; TNFR_16.
DR InterPro; IPR034046; TNFRSF16_N.
DR PANTHER; PTHR46605; TUMOR NECROSIS FACTOR RECEPTOR; 1.
DR PANTHER; PTHR46605:SF3; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16; 1.
DR Pfam; PF00531; Death; 1.
DR Pfam; PF18422; TNFR_16_TM; 1.
DR Pfam; PF00020; TNFR_c6; 3.
DR PRINTS; PR01966; TNFACTORR16.
DR SMART; SM00005; DEATH; 1.
DR SMART; SM00208; TNFR; 4.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF57586; TNF receptor-like; 3.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
DR PROSITE; PS00652; TNFR_NGFR_1; 1.
DR PROSITE; PS50050; TNFR_NGFR_2; 3.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261660};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..432
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018774675"
FT TRANSMEM 243..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 56..97
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 56..97
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 98..136
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 98..136
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT DOMAIN 138..177
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 138..177
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 358..417
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
FT REGION 192..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 274..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..212
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 76..89
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 79..97
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 115..128
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 118..136
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 139..154
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 432 AA; 46644 MW; 90998311DF81C9EB CRC64;
MNSAFTALLV GLVGVLANKE ECLSGQYTTS GECCLQCQPG EGVIKACGVT QTDCAPCLDS
ETFSENFSHE DICQPCTVCT GLLRMKAPCT DSNDAECVCN YGYYLSQISQ RCEPCTKCPE
GQGMLFSCDY SHDTVCEECI GETYSDQESS REPCIPCTTC DEGEMLQGCT SVTDTVCQVN
YSVFPSIPFN GSPMPPFDEL PPDGPPEGPP PDGASTESTT TTTTTTTGDS QERLYQGLND
KLIPIYCSIL AAVVVGLVAF IIFKKWNSCK QNKQGANNCT ANQNQTPSPE GEKLHSDSGI
SVDSQSLQEQ LAQTQAQTVV TMDEEPCLLL PLHTREKVEK LLFNGSEGDD CNHMDDSDWC
NLAGLLGYEE ERIATFGQEE HPVRALLSDW ASKDSASIDA LCTALRKINR DDIAQSLVLS
PSVTKPTATS VV
//
