ID   A0A3Q3GB98_9LABR        Unreviewed;       491 AA.
AC   A0A3Q3GB98;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Fascin {ECO:0000256|PIRNR:PIRNR005682};
OS   Labrus bergylta (ballan wrasse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Labriformes; Labridae; Labrus.
OX   NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000030451.1, ECO:0000313|Proteomes:UP000261660};
RN   [1] {ECO:0000313|Ensembl:ENSLBEP00000030451.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|PIRNR:PIRNR005682}.
CC   -!- SIMILARITY: Belongs to the fascin family.
CC       {ECO:0000256|ARBA:ARBA00007415, ECO:0000256|PIRNR:PIRNR005682}.
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DR   AlphaFoldDB; A0A3Q3GB98; -.
DR   Ensembl; ENSLBET00000031860.1; ENSLBEP00000030451.1; ENSLBEG00000022988.1.
DR   GeneTree; ENSGT00950000183157; -.
DR   OrthoDB; 5484756at2759; -.
DR   Proteomes; UP000261660; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:InterPro.
DR   GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR   CDD; cd00257; Fascin; 4.
DR   Gene3D; 2.80.10.50; -; 4.
DR   InterPro; IPR008999; Actin-crosslinking.
DR   InterPro; IPR010431; Fascin.
DR   InterPro; IPR022768; Fascin-domain.
DR   InterPro; IPR024703; Fascin_metazoans.
DR   PANTHER; PTHR10551; FASCIN; 1.
DR   PANTHER; PTHR10551:SF24; FASCIN-2; 1.
DR   Pfam; PF06268; Fascin; 4.
DR   PIRSF; PIRSF005682; Fascin; 1.
DR   SUPFAM; SSF50405; Actin-crosslinking proteins; 4.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203,
KW   ECO:0000256|PIRNR:PIRNR005682};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR005682};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212,
KW   ECO:0000256|PIRNR:PIRNR005682};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261660}.
FT   DOMAIN          21..132
FT                   /note="Fascin"
FT                   /evidence="ECO:0000259|Pfam:PF06268"
FT   DOMAIN          143..253
FT                   /note="Fascin"
FT                   /evidence="ECO:0000259|Pfam:PF06268"
FT   DOMAIN          265..374
FT                   /note="Fascin"
FT                   /evidence="ECO:0000259|Pfam:PF06268"
FT   DOMAIN          389..491
FT                   /note="Fascin"
FT                   /evidence="ECO:0000259|Pfam:PF06268"
SQ   SEQUENCE   491 AA;  54647 MW;  A3F807C729F82D63 CRC64;
     MPTNGINKAL KLQFGLINYE NRYLTAEAFG FKVNASGISM KKKQIWTLEQ DEQDGQVVFL
     RSHLGRYLAS DKDGKMTCGA EKPDPDCRFL IVPQSDGRWA LQSEPYLRYF GGSADYLSCF
     AQAIGEQELW AVHLALHPQA SLLSVARKRY AHLSASDGEI SVDSNIPWGV DSLVTLVYLD
     GKYSLKTCDS RFLRNDGKLV KENTNTTSFT LELKSGKLAF KDCDGKYLSP LGPTGTLRSG
     RCSKPGKDEL FDLEESHPQV VFQAANKRFV SVKQGVSISA NQDVETDMET FQMEIHKDTK
     KPMFRTNGGS YWTLVSHGEI QSTATEVEVN TMFDIEWRGK RVALKASNGK YVCTKKNGQL
     SAVSDAVGDG ELFLMKLINR PMLILHGENG FVCHHKSSNT LDANRSVYDI FSLIFNDGAY
     YVKSVNGMFW YVSSSGLVCS DGEKPEDFFL EFLEHGCVAI KGSNGKYLRG DKGGTLMGDA
     TTVDRSCLWE Y
//