ID   A0A3Q3GFR6_9LABR        Unreviewed;      1512 AA.
AC   A0A3Q3GFR6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=DEP domain containing 5, GATOR1 subcomplex subunit {ECO:0000313|Ensembl:ENSLBEP00000032142.1};
GN   Name=DEPDC5 {ECO:0000313|Ensembl:ENSLBEP00000032142.1};
OS   Labrus bergylta (ballan wrasse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Labriformes; Labridae; Labrus.
OX   NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000032142.1, ECO:0000313|Proteomes:UP000261660};
RN   [1] {ECO:0000313|Ensembl:ENSLBEP00000032142.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   STRING; 56723.ENSLBEP00000032142; -.
DR   Ensembl; ENSLBET00000033584.1; ENSLBEP00000032142.1; ENSLBEG00000024189.1.
DR   GeneTree; ENSGT00390000016559; -.
DR   InParanoid; A0A3Q3GFR6; -.
DR   Proteomes; UP000261660; Unplaced.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd04449; DEP_DEPDC5-like; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000591; DEP_dom.
DR   InterPro; IPR045838; DEPDC5_CTD.
DR   InterPro; IPR027244; IML1.
DR   InterPro; IPR048255; IML1_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR13179; DEP DOMAIN CONTAINING PROTEIN 5; 1.
DR   PANTHER; PTHR13179:SF8; GATOR COMPLEX PROTEIN DEPDC5; 1.
DR   Pfam; PF00610; DEP; 1.
DR   Pfam; PF19418; DEPDC5_CTD; 1.
DR   Pfam; PF12257; IML1; 1.
DR   SMART; SM00049; DEP; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50186; DEP; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261660}.
FT   DOMAIN          1118..1177
FT                   /note="DEP"
FT                   /evidence="ECO:0000259|PROSITE:PS50186"
FT   REGION          1024..1045
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1427..1446
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1512 AA;  170905 MW;  3923A927CBC59A9A CRC64;
     MKASKSYKLV LHKKGFGGSD DELVVNPKVF PQVNLGDIIE IAHPTDEYSP LLLQVKSLKE
     DLQKEIISVD QTVAQAFKLR AYQDVIISIV DPKDVTLDLV ELTFKDQYIG RGDMWRLKKC
     LVSTCAYVTQ KVEFAGIRAQ ASELWVKGEK VTCGYISEDT RVVFRSTSAM VYIFIQMSCE
     MWDFDIYGDL YFEKAVNGFL SDLFAKWKEK NCSHEVTVVL FSRTFYIANT IEEFPEILRG
     SIRQDHEGRF YEDFYRVVAQ NERRDEWTSL LVTIKKLFIQ YPVLVRLEEA GNGFPVSYNS
     TAAEGNYLEA INLSFNVFDK HYINRNFDRT GQMSVVITPG VGVFEVDRLL MILTKQRMID
     NGIGVDLVCM GEQPLHAVPL FKLHNRTTPG DSRVGDDYNL PHWINHSFYT SKSQNSCGSF
     TPRIKLAGRK VNSQFLKNSL GTPKDSDNSL PIQVDYDAYD AQVFRLPGPS RVQRSTNFRI
     GRDKEISGRK SWGSVDVTAG IGVSPPIRSV GPEEQRSLAS DDSLGPVSNV LLIPRLPPAQ
     YEVSSSLGYT STRELLEKMM DSQRDSSAPG RFTVGSAEST LHIRPGGYTP QRALINPFTP
     SRMPMKLTSN RRRWMHTFPV GPSGEAIQIH HQTRQNMAEL QGSQKRDPAH TSAELLELAY
     HEATGRRTTL RQGGDNSLYI GGGMEELTGS PGNNSTLLIS APPTVPSFCC TVGVDWKSLT
     TPACLPLTTD YFPERQTLQN DYTEGCYDLL PHSDLERRED ESPVMSASQV FEEFICQRLM
     QGYQIIVQPN NRKQQPSVAT PLGSSPHYSR GLVSLRRAEE ENVYWLSMGR TFHKVCLKDK
     IITVTRYLPK YPYESAQIPY SYSLCPPHSD AQFVFCWVEF GHERLEEYKW NYLDQYICSA
     GSEDFSLIDS LKFWRTRFLL LPAGGARRVA DGEGHWDVYG DGAGAGMSSS GDWVLLDGFI
     RYLEGLNRIR RRHRSDRIIR KGTPLKGLQV TTHPLPFPTE PLAPPQGKKG TSALSALLEM
     EQNQKTLEEQ QQAKPQTTVG DLTSVATAPT YVDSPRRVSR PKIQPVHTTD HVCVLSGQSA
     AGALSLSSSS TLLEILEAIK HPTTGVQLLP EQKGLPINCF ISAEVVHWLV NNVEGMATQG
     MAVDIMQKML DEGLVAHASG DAMRTFVYGF YFYRIAIWIF NIQRWSTAAR EDFAMFQRKW
     FEVAFVLEEP QACNLPAFLL PWLPSRPASY ASRHSSFSRS FGGRSQAAAL LAATVPEQKT
     VTLDVDVNNR SERTEWCSCY YHGNFSLNAA FEIKLHWMAV TAAVLFEMVQ GWHRKAASCG
     FLLVPVLEVP FALTSYLYGD PLRAQLFIPL NIHCLLKNSS DNLFEGFEPE TYWDRMQLFQ
     EAILYRFGFV HDKFSPSAFN FPSENKPQYI HVTGTVFLQL PYSKRKYSSG QQRRRRNSTT
     SNSQGAFGGE ERVGYYWAYN TMLTKAWRTG VLGDERLAER LLRDFTDFCI NKDNRLLNFW
     DSCQEKMNAS AP
//