ID A0A3Q3GMM2_9LABR Unreviewed; 778 AA.
AC A0A3Q3GMM2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Cyclin-F {ECO:0000256|ARBA:ARBA00019493};
OS Labrus bergylta (ballan wrasse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrus.
OX NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000035132.1, ECO:0000313|Proteomes:UP000261660};
RN [1] {ECO:0000313|Ensembl:ENSLBEP00000035132.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Essential for the control of the cell cycle at the G2/M
CC (mitosis) transition. {ECO:0000256|ARBA:ARBA00003222}.
CC -!- SUBUNIT: Interacts with the CDK1 protein kinase to form a
CC serine/threonine kinase holoenzyme complex also known as maturation
CC promoting factor (MPF). The cyclin subunit imparts substrate
CC specificity to the complex. {ECO:0000256|ARBA:ARBA00025821}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome, centriole {ECO:0000256|ARBA:ARBA00004114}.
CC Cytoplasm, perinuclear region {ECO:0000256|ARBA:ARBA00004556}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC {ECO:0000256|ARBA:ARBA00006955}.
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DR AlphaFoldDB; A0A3Q3GMM2; -.
DR STRING; 56723.ENSLBEP00000035132; -.
DR Ensembl; ENSLBET00000036628.1; ENSLBEP00000035132.1; ENSLBEG00000026388.1.
DR GeneTree; ENSGT00810000125541; -.
DR InParanoid; A0A3Q3GMM2; -.
DR OrthoDB; 3020936at2759; -.
DR Proteomes; UP000261660; Unplaced.
DR GO; GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd20521; CYCLIN_CCNF_rpt1; 1.
DR CDD; cd22082; F-box_FBXO1; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR InterPro; IPR048258; Cyclins_cyclin-box.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR PANTHER; PTHR10177:SF496; CYCLIN-F; 1.
DR PANTHER; PTHR10177; CYCLINS; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR Pfam; PF12937; F-box-like; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SMART; SM01332; Cyclin_C; 1.
DR SMART; SM00256; FBOX; 1.
DR SUPFAM; SSF47954; Cyclin-like; 2.
DR SUPFAM; SSF81383; F-box domain; 1.
DR PROSITE; PS00292; CYCLINS; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cyclin {ECO:0000256|ARBA:ARBA00023127, ECO:0000256|RuleBase:RU000383};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000261660}.
FT DOMAIN 28..75
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REGION 613..636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 662..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 737..778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 686..706
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 754..768
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 778 AA; 86241 MW; D4AB14724154BEFD CRC64;
MKAGVVHCRC SKCYSIPARK RVRKRTPALT LLSLPEEVLL CVLQCLSAED LLSVRAVHSQ
LRDIVDNHSS VWARVSFRDT WPSPKTLWLF ERAAEKGNFE AAVKLGIAYL YNEGPLLSDE
GRADVCGRKA SHFFSLAESL HSPLTDPFIW VFIRPPWSPT GSCCKAVVFD RLKAECDSNV
EKRGPLLHCL ARVLQLFEGD ERRSDAISML KESSQAGCLQ SSYMLWEHNR KAAMADPGRY
LQCVRTLRDY AGKGCWEAQV SLAKVCSSGN PLGLESKACS DLVAQLFSCN PASGHCTQGI
LKRGIKDTMR YILVDWLVEV TTMKDFSSLT LHVTVGCVDR YLALRSVPKA RLQLLGIACM
VVCTRYISKE ILTIREAVWL TDNTYKYEDL VRMMGEVVAV LEGKIRSPTL LDYGEVLLSL
LPLERRTTHL FSYICELSLL YSALSSPPPA KLACAALLLT RALHHYAPLW PSQLVDYTGF
SKQDLVSLAV LLFVKCFSQD VPKDYRHVSL TGVKQRFEDE AYRSISKERV MDYKELCQLL
EIPEVEPQME PPSPTGQPAD IHTFLASPSS TSKRKRDDAM QAHRACFMAT PTAELSNQEE
TLLGDIMDWS LDTSCSGYEG DQEEESEGEK DSDASMISIK LSPLTEDEKI LEHCRALSSD
EDSFCEAEKD ESKDGQAPNP MSFPADLHTS GYSSIQSVSP SSTCSSSSLM PCTFKTLTTS
LGAASANATP GFRLLVPMQR PRGTSGKQVK RKNSAAHSGG EVEREGDEYS ANAGFLSL
//
