ID   A0A3Q3GMS9_9LABR        Unreviewed;      1878 AA.
AC   A0A3Q3GMS9;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Lactase-phlorizin hydrolase-like {ECO:0000313|Ensembl:ENSLBEP00000034676.1};
GN   Name=LCT {ECO:0000313|Ensembl:ENSLBEP00000034676.1};
OS   Labrus bergylta (ballan wrasse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Labriformes; Labridae; Labrus.
OX   NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000034676.1, ECO:0000313|Proteomes:UP000261660};
RN   [1] {ECO:0000313|Ensembl:ENSLBEP00000034676.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   STRING; 56723.ENSLBEP00000034676; -.
DR   Ensembl; ENSLBET00000036163.1; ENSLBEP00000034676.1; ENSLBEG00000026000.1.
DR   GeneTree; ENSGT00940000155324; -.
DR   InParanoid; A0A3Q3GMS9; -.
DR   Proteomes; UP000261660; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 4.
DR   InterPro; IPR001360; Glyco_hydro_1.
DR   InterPro; IPR018120; Glyco_hydro_1_AS.
DR   InterPro; IPR033132; Glyco_hydro_1_N_CS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10353; GLYCOSYL HYDROLASE; 1.
DR   PANTHER; PTHR10353:SF36; KLOTHO (MAMMALIAN AGING-ASSOCIATED PROTEIN) HOMOLOG; 1.
DR   Pfam; PF00232; Glyco_hydro_1; 4.
DR   PRINTS; PR00131; GLHYDRLASE1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 4.
DR   PROSITE; PS00572; GLYCOSYL_HYDROL_F1_1; 2.
DR   PROSITE; PS00653; GLYCOSYL_HYDROL_F1_2; 2.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Glycosidase {ECO:0000256|RuleBase:RU004468};
KW   Hydrolase {ECO:0000256|RuleBase:RU004468};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261660};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..1878
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018753779"
FT   TRANSMEM        1835..1858
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   ACT_SITE        1234
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10055"
FT   ACT_SITE        1697
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10055"
SQ   SEQUENCE   1878 AA;  214182 MW;  27551B752A7FFFEE CRC64;
     MLLPGKLFSL CLITVFGCMC QKHEDPRQAV FLAGPMTSEQ VEGLSGNPSD WALLDTFDCG
     YALPPEFQQY FKFLQTTGVT HYKVPLSWTQ LLPTGLSSQP QQAAVSCYQT LMKQLLDVGL
     QPLVILHGSA VPEALRSKYG GWESQELVEM FQQYAEFVFG LFGELTDSWL TLSCLDELRD
     AELQNALDAH ISVYQRYHQL FPGRGRRSMF YDITCRDLIR YSDFISIKIH YDCTIGRELA
     EELQNVLVCR NVLQNIVNSP HLVYFIAIRS SASSILPFQT FAEKMFVGFL LKYVIQFNFQ
     HLVPYIRNTL PTSSCSMTYC KVWSDFATKT LSEPDALLNE SFPDGFQWAT SSESFKVEGG
     WSEDGKGETI WDRWGHENHF FDNHTADLAC DSYNKVDYDV YLLRGLNVNT YQFSISWARI
     FPSGQRGSQS EKGVLYYDKL INALIESGIQ PVVTLYHWDL PQALQDYGGW TNASIVEAFK
     DYADFCFSRF GDRVKTWNTF SSPWVVSHAG YGTGEHPPGV KDYVVASYKV THNILKSHAE
     AWHVYNDRYR KAQGGEVGIA LNSDWAEPKD PSRPEDTAAA DRYLQFMLGW FAHPIFVNGD
     YPETLKTQIE QKRNKCPLSE PARLPVFTAE ESKRIHGTAD FLGLNHYTSW LINSTDGGCI
     PGPHGVGDFQ AHVDPSWSST VSDWIYSTPW GLRRLLNYIS KEYLNVTKVP IHITGNGMPT
     EYSGDTLDDT HRVDYLKSYI NEALKAIHLD GVNVQRFTVQ SLMDSFEGPQ GHSERFGLHH
     VDFDLPDRPR TPKQSAYFYS KIIENNGFAS REKLFNAQET KNIEPNKVSS LPPSTVPSQT
     KNVWSRFSSQ TNFQRKLYHY GTFPDGFSWG VSSSAYQIEG AWNADGKGPS VWDTFTNETS
     SIPGNADGDV ACDSYNRLDE DLYMLRALRV KSYRFSLSWS RIFPDGRRTS LNQKGVDYYN
     RLIDELLAYN ITPMVTLYHW DLPQALQNLS GWENEDMINI FNEFCDFCFA TFGDRVKFWM
     TFNQPHTIAW SGYGLGQIPP NVKNPGTAPY RVAHNLIKAH AKAYHTYDDK YRKSQGGQVS
     IALNADWVEP KDVNAPREVV AADRALQFQL GWFAHPIFKN GDYPDAMKWQ VGNKSELQGL
     SETRLPAFTE EEKRFIKGTA DMFCVNHYTT KIVGHLTARL SPPSYEYDKD LSEAEESDSP
     STAISKQKAV AWGLRRLLIW IKEEYGDPEI YITENGVATD TKTTVDDIDR VFYYKTYVDE
     ALKAHNLDGV RVKGYIATSL MDSFEWLNGY KVGFGLHHVD FTNPHRPRTP KRSAHYYYKV
     MKDNGFPLPD DERTLYEEFP MAFNWSTASA SYQIEGSWRT DGKGLSIWDK FAHTPLRVDN
     SYNGDIACDS YNKVDEDVAV LKKLKVTHYR FSVSWSRVLP DGTYNFINEA GLDYYHRLLD
     ALKAANIEPQ VTLYHWDLPL ALQKIGGWEN EIMVRRFYEY ADVLFSRLGQ KVKFWITLNE
     PYIVANLGYG YGTFAPGIIG KQYIAAHNLI KAHAEAWHLY NRKYRAKQGG IISITINSDW
     AEPRNPYKQE DVDAAKRYLQ FFIGWFAHPI FNGDYPEVMK KTIHERSLAA GLPKSRLPEF
     TPEEIQRIKG THDYFGFNHY TTVLSYPVDL GKGTGTTHDR TWIESGSFWL KITPFGFRKI
     LKFIKDEYGN PPVYVTENGI SERGAVDLND IHRKHYYEKY INQALKAQVL DGVDLRGYTA
     WSLMDNFEWA AGYSERFGLF FVNRSDPNLP RIPKNSASRY ASIISCNGFP DPALGPHECL
     NPEPEDTTLL TTTPIPPVNM VNFLGLELSS DDAGVALYVL FAVLLVSVLG VIFVVYGLMK
     TRRKLKKTAV ASLQMEKM
//