ID A0A3Q3GPR8_9LABR Unreviewed; 1279 AA.
AC A0A3Q3GPR8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Nuclear factor of activated T cells 5 {ECO:0000313|Ensembl:ENSLBEP00000035411.1};
OS Labrus bergylta (ballan wrasse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrus.
OX NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000035411.1, ECO:0000313|Proteomes:UP000261660};
RN [1] {ECO:0000313|Ensembl:ENSLBEP00000035411.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q3GPR8; -.
DR STRING; 56723.ENSLBEP00000035411; -.
DR Ensembl; ENSLBET00000036911.1; ENSLBEP00000035411.1; ENSLBEG00000026588.1.
DR GeneTree; ENSGT00940000155213; -.
DR InParanoid; A0A3Q3GPR8; -.
DR Proteomes; UP000261660; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd07882; RHD-n_TonEBP; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.340; Rel homology domain (RHD), DNA-binding domain; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR008366; NFAT.
DR InterPro; IPR015646; NFAT5_RHD_DNA-bd.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR032397; RHD_dimer.
DR InterPro; IPR011539; RHD_DNA_bind_dom.
DR InterPro; IPR037059; RHD_DNA_bind_dom_sf.
DR PANTHER; PTHR12533; NFAT; 1.
DR PANTHER; PTHR12533:SF10; NUCLEAR FACTOR OF ACTIVATED T-CELLS 5; 1.
DR Pfam; PF16179; RHD_dimer; 1.
DR Pfam; PF00554; RHD_DNA_bind; 1.
DR PRINTS; PR01789; NUCFACTORATC.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS50254; REL_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000261660}.
FT DOMAIN 268..447
FT /note="RHD"
FT /evidence="ECO:0000259|PROSITE:PS50254"
FT REGION 41..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 121..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 246..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 694..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 870..898
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 919..946
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 979..1001
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1040..1061
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 756..800
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 64..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1279 AA; 139128 MW; 38E8FA4ECBB8CEEC CRC64;
MPSDFISLFS GDLDLNPPRA FYSKESAYDL LPGKLQLSST RQSLKVMSQK SGGEAGPPPS
AAVASDAMSS SMTMEGPRSA FPTSSSSIIH SSTSASDQNL AHCGNVDPDD IRSSRAGLEV
VGAESGNGNG SSGGNCRGSS EITPSKRRTV LNISPPPQDL FDDSQMSCQG EASLDSEQSN
SIWMDDSLSN FSIMSTVSYN DNTEVPRKSR KRTPRQRPGP KSVPTGEGSM DMFDADSAKA
PHFVLSQLGP DTKTGQKGSS DDPPTTKQKG GTLLIQHPQK CEGKELKILV QPETQHRARY
LTEGSRGSVK DRTQQSFPTV KLEGVNEPVV LQVFVGNDAG RVKPHGFYQA CRVTGRNTTA
CKEVDIDGTT VIEVSLDPST MMTLAVDCVG ILKLRNADVE ARIGVAGSKK KSTRARLVFR
VNIPRPDGSV LTLQTPSSPI LCTQPAGVPE ILKKSLHCCS VRGGEEVFII GKNFLKDTKV
IFQENVSDET SWKAEAEIDM ELFHQNHLIV KVPPYQSQSI TSSVCVGIYV MTNAGRSHDV
QPFTYTPDTA KNDIPVKKEA PSPVKTCPFD EQIKVLDGAL IPSLLPLVKR EDVTPMEISN
LQSSGVFKQT KDLCTAQQSP DGTAGHLNKS RPFSNSLSQP ASDSEKSQAT VFTNTEPLST
IQKQDIAATS SFSVPADSLL QQSSQQFLLE REGLRQERPG SGSGAVGRLC GEPAPQQQQQ
QIPLFPPDEV AQLEEAVRQL KAKGFCNLPL QSDDSLAKQQ QQHIQHQQQI QKQQIQQQQL
HQQHQQQQQQ QQVLENIQQQ LFQSQIQMQC GMFQDASQGK NSEQQSSSQV VVPNQGTLFQ
QAQQQQQQQQ QQAALFQQAS DLLSIQNNFL QQTPTHPSPP MFHNPTSLAE TQDQQGGLFQ
KASQGQVQAT LFQNTMTVLQ SPDQQPSTPG LFLTQSSSAQ QQQQQQQQQQ QLAFLTALQT
PAPEPQSVYQ AQTQLSPIQQ RGPMEQQQPS QAQPHTQPAQ QASLFQNISQ HPANTLSSGQ
QQQQQAGLLF CNNRLSSPDQ TSSLMFSSQG QMPPLTSSSL VSQETQNPPL LFSQASMVTV
NQQDRSEPMA LGNPTDPRQQ VMFQEQQPMQ LGSSSNSRQE QPVGLFMPQS NIASLQGELA
AQELAQSAMF ASQNGVANLQ TTTSSPVQQP GTLFQTAVSG NINQPSQPPQ PGLFLYGIQN
ECGQLMNTPG NTLSDQIIAI SQSGQNQRES EAHIQSLLSQ SLSQSGSVQN SMTASQNMEK
IDDLLVSLQE SGSNLTRSY
//
