ID A0A3Q3GQI0_KRYMA Unreviewed; 234 AA.
AC A0A3Q3GQI0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Transmembrane emp24 domain-containing protein 1 {ECO:0000256|ARBA:ARBA00040024};
DE AltName: Full=p24 family protein gamma-1 {ECO:0000256|ARBA:ARBA00041274};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000025617.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000025617.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004115}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004115}.
CC Endoplasmic reticulum-Golgi intermediate compartment membrane
CC {ECO:0000256|ARBA:ARBA00004151}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004151}. Golgi apparatus, cis-Golgi network
CC membrane {ECO:0000256|ARBA:ARBA00004619}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00004619}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003827}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU003827}.
CC -!- SIMILARITY: Belongs to the EMP24/GP25L family.
CC {ECO:0000256|ARBA:ARBA00007104, ECO:0000256|RuleBase:RU003827}.
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DR RefSeq; XP_017281077.1; XM_017425588.1.
DR AlphaFoldDB; A0A3Q3GQI0; -.
DR STRING; 37003.ENSKMAP00000025617; -.
DR Ensembl; ENSKMAT00000025940.1; ENSKMAP00000025617.1; ENSKMAG00000018977.1.
DR GeneID; 108241444; -.
DR KEGG; kmr:108241444; -.
DR CTD; 791158; -.
DR GeneTree; ENSGT00940000158445; -.
DR OMA; PAGRQEC; -.
DR OrthoDB; 601480at2759; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR015720; Emp24-like.
DR InterPro; IPR009038; GOLD_dom.
DR InterPro; IPR036598; GOLD_dom_sf.
DR PANTHER; PTHR22811; TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22811:SF40; TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF01105; EMP24_GP25L; 1.
DR SMART; SM01190; EMP24_GP25L; 1.
DR SUPFAM; SSF101576; Supernatant protein factor (SPF), C-terminal domain; 1.
DR PROSITE; PS50866; GOLD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003827};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022927}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..234
FT /note="Transmembrane emp24 domain-containing protein 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018688609"
FT TRANSMEM 200..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 48..130
FT /note="GOLD"
FT /evidence="ECO:0000259|PROSITE:PS50866"
SQ SEQUENCE 234 AA; 26617 MW; 728FBE17F29F84AB CRC64;
MGALRMKIKP GGRLLGLAVV ILWCAASVRC FRPSQDSEFT FLLPAGRSEC FYQTAIKNGT
MEVEYQVIAG AGMDVDFTIL SPHGVRVIIE SRHSDGVHVV EPTEEGDYEI CFDNSFSRFS
EKMVFFEIII EGQGGDVGGD DEWPGLEEPD GNLLEYKLDD IRESMDSLHK RLERSRQMQT
VLRAFEARDR NLLEDNLWRV SFWSCASVLV MLGVALTQVY TVRKLFDDKR RVYT
//
