ID A0A3Q3GQN1_9LABR Unreviewed; 945 AA.
AC A0A3Q3GQN1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Seizure protein 6 homolog {ECO:0000313|Ensembl:ENSLBEP00000033579.1};
GN Name=SEZ6 {ECO:0000313|Ensembl:ENSLBEP00000033579.1};
OS Labrus bergylta (ballan wrasse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrus.
OX NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000033579.1, ECO:0000313|Proteomes:UP000261660};
RN [1] {ECO:0000313|Ensembl:ENSLBEP00000033579.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR AlphaFoldDB; A0A3Q3GQN1; -.
DR STRING; 56723.ENSLBEP00000033579; -.
DR Ensembl; ENSLBET00000035050.1; ENSLBEP00000033579.1; ENSLBEG00000025291.1.
DR GeneTree; ENSGT00940000156995; -.
DR InParanoid; A0A3Q3GQN1; -.
DR Proteomes; UP000261660; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00033; CCP; 5.
DR CDD; cd00041; CUB; 2.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 5.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 3.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR PANTHER; PTHR45656:SF1; SEIZURE PROTEIN 6 HOMOLOG; 1.
DR Pfam; PF00431; CUB; 2.
DR Pfam; PF00084; Sushi; 5.
DR SMART; SM00032; CCP; 5.
DR SMART; SM00042; CUB; 2.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 5.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 3.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS50923; SUSHI; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261660};
KW Signal {ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..945
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018736401"
FT TRANSMEM 879..901
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 314..373
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 375..486
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 489..550
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 552..663
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 667..726
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 728..791
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 795..856
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 30..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..140
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 375..402
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 697..724
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 945 AA; 103229 MW; 0093CEBD0B18A2B8 CRC64;
MKAITDYFAL LLVLVAAGTD MSTKASEDAL SITPGVPQES RSGLYPTTQD SGGRPPVVTT
APPVNVLNHH PVYRNPHQQH DLLNPRGQPN YFEDSGGSTP PPKTLQASDV TTESSDVRTT
VVMHTSAPAA HSSSHVPVTS EVLKDSEHTE MSPSSSPAAG EEDEARKNQT GPQQTVRPSR
DEEETTTTTI TTTTIITTMQ SPVPCQLNLT GPEGFIEAPP QSSSAFHSTI DCSYIITVYM
GYGVEVQVMN VNLSEGDKVV FEDVGHRENT MLANESILMR GLVVRSHSNQ ISIRFHSPRS
QAASVLLRYQ AFVLSCVFPQ RPLYGDVSVS SLHSGGEAFF SCLTGYQLQG PSVLTCRNAS
TPYWSGKEPH CLAACGGLMR NITVGRIVSP GFPSNYSNNL TCHWLLEAPE GQKLHVHFEK
VALAEDDDRL LIKNGNSIDA AALYDSYEVE YLPNEGLLSS SKHLFIELTT DAAGTSTGMA
IRYQAFAAGH CYEPFVKYGN LTSSDITWAV GAVVEFTCDP GYTLEQGSVT IECMDPNNPQ
WNETEPACRA VCSGEITDSA GVVLSPNWPE AYDKGQDCIW GIHVEEDKRI MLDIQVLNIG
KNDLVTFYDG DDLTAKVLGQ YGGSKSRFKL YTSTSDVTIQ FQSDPATNVY GYGNGFIVHF
FEVARNDTCP ELPEITNGWK STSHPELVQG TVVTYQCYPG YQVIGAELLM CQWDLTWSGD
LPSCERVVSC PDPGKVEHSR RVLSGPHFTV GSTIQYVCNK GFTLSGNSLL TCFNRGSAGP
RWNQKLPRCI PETFEPCSHP GTPTYGIPDS TKLHFQPGEM LHYSCLSGHQ LLGEPVLHCV
PGHPSQWSGL PPVCKGHPAD DEHRLDVSTA DLRMEGAQAA FVVIIPVILL LVLIIGIYLY
FSKVQRKPLR LSLASSLPYE NISAESTFDN TVHETTETRE YEVSI
//
