ID   A0A3Q3GV99_9LABR        Unreviewed;       768 AA.
AC   A0A3Q3GV99;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE            EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
OS   Labrus bergylta (ballan wrasse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Labriformes; Labridae; Labrus.
OX   NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000038412.1, ECO:0000313|Proteomes:UP000261660};
RN   [1] {ECO:0000313|Ensembl:ENSLBEP00000038412.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC       receptor class 4 subfamily. {ECO:0000256|ARBA:ARBA00034734}.
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DR   AlphaFoldDB; A0A3Q3GV99; -.
DR   Ensembl; ENSLBET00000039990.1; ENSLBEP00000038412.1; ENSLBEG00000028630.1.
DR   GeneTree; ENSGT00940000164289; -.
DR   Proteomes; UP000261660; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR   GO; GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR047170; PTN12/18/22.
DR   InterPro; IPR000242; PTP_cat.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   PANTHER; PTHR45983; TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR45983:SF3; TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 12; 1.
DR   Pfam; PF00102; Y_phosphatase; 1.
DR   PRINTS; PR00700; PRTYPHPHTASE.
DR   SMART; SM00194; PTPc; 1.
DR   SMART; SM00404; PTPc_motif; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261660}.
FT   DOMAIN          29..294
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          208..285
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
FT   REGION          308..768
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        314..336
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        357..372
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        396..474
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        499..551
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        599..660
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        702..734
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        750..768
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   768 AA;  84386 MW;  E47B9143F402BCFC CRC64;
     MDQAGILRKF IQGVKAMSEG DEERGEDNFG SDFMRLRRLS TKYRTEKIYP TNVGEREENV
     KKNRYKDILP FDHSRVKLTL KTTNQDTDYV NANFIKGMDG PEAYIATQGP LQNTVIDFWR
     MNWEYNVAVI VMACREFEMG RKKCERYFPL LVEEPMSFGP FRISYESEQA RTDYVIRTLM
     VEYENESRRI TQFHYMNWPD HDVPSSFDSI LDMIGLMREY QENDDVPICV HCSAGCGRTG
     AICAIDYTWN LLKAGKIPED FNVFRLIQEM RTQRHSAVQT KEQYELVHRA IAQIFQKQLL
     LLESPTNTQI HDGMDESSPD KASHQSDDER WDTPPPKPPR IRSSQAEGDV KEEILQPPEP
     HPVPPILTPS PPSAFPTVTN VRQDNDRYHP KPVIHVLATS QTQNKEADKQ QNKSTSLNKQ
     TSPSEQKDQD LQGLKQQTQV SNLDLNENYN NKTSSTSTKT ECGQTPSSPL SSAVECSGAP
     RIERKLSIEI KKVPLQEGPR SFDTSTSMGV AGGISNSSTN NTGMLQRSHA FKARASQSLL
     TSSSSLSEDS GTEGGAGGYG ESNADGGVLT RPNHLPVKSE KLETPGGGER AEVKAGHAAW
     SQSCSSPDKH FPKTTSSSSS SSERVAPSSS SSSHLSSSSS SSSSTPVRTA LSFTNPLHSD
     NSDNEEGDGE MSGGKEGYRT TATAVVTASL HHGDQQPIRK VSPMSIAGQS TPSPSANTAN
     PLELKTSASA EWSGSHKDVS DCVKKTSPAD PGSAGTTATS KPDLGGVQ
//