ID A0A3Q3H2K1_9LABR Unreviewed; 1659 AA.
AC A0A3Q3H2K1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=FERM and PDZ domain-containing protein 4-like {ECO:0000313|Ensembl:ENSLBEP00000037873.1};
OS Labrus bergylta (ballan wrasse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrus.
OX NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000037873.1, ECO:0000313|Proteomes:UP000261660};
RN [1] {ECO:0000313|Ensembl:ENSLBEP00000037873.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR Ensembl; ENSLBET00000039436.1; ENSLBEP00000037873.1; ENSLBEG00000028253.1.
DR GeneTree; ENSGT00950000183035; -.
DR Proteomes; UP000261660; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13183; FERM_C_FRMPD1_FRMPD3_FRMPD4; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR049385; FAK1-like_FERM_C.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR041779; FRMPD1/3/4_FERM_C.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46221:SF4; FERM AND PDZ DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR46221; FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER; 1.
DR Pfam; PF21477; FERM_C_FAK1; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00295; B41; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000261660}.
FT DOMAIN 75..152
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 201..516
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 567..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 698..738
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 756..775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 788..901
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 930..1051
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1063..1086
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1118..1146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1180..1252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1264..1292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1397..1454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1469..1530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1549..1617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 636..656
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 872..901
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 935..951
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 967..998
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1026..1051
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1122..1144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1180..1194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1420..1441
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1489..1503
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1505..1519
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1555..1572
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1573..1600
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1601..1617
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1659 AA; 181289 MW; 70EFE315CAC5DCA8 CRC64;
MFGFSKMPKL SGHKNKMSGW PPPGPGSWSG LQGPPYSWES MNSSREGRDC LTSQVSTSSS
LEEVHLDGVP PAPRLIEMRR DPVLGFGFVA GSEKPVVVRS VTPGGPSEGK LLPGDEIILI
NDEPVSSAQR ERVIDLVRSC KESIVLTVIQ PYPSPKSAFI SAAKKAMLKS NPVKVRFAEE
VIINGQVPNP VKDNSLLFMP NVLKVYLENG QTKSFRFDSS TSIKDVILTL QEKLSIKCIE
HFSLVLEQRE EGSGSKLLLL HEQEMLTQVT QRPGCDKMKC FFRVSFVPRD PVELLRRDAV
AFEYLYVQSC NDVVLERFGP ELKYDAALRL AALQMYILTM TTRQSQKVSL KYIQKEWGLP
LFLPPVVLSS MKEKNIKKAL THILKTNQNL VPPGKKLTAL QAKVHYLRYL SELRLYGGRE
FKSILLQGEK QTDVTLLVGP RYGISHVINA RTNLVALLAD FSHVNRIEIL TEDETNVRLE
LHVLDVRPIT LIMDSSDAMN LACLTAGYYR LLVDARRSIF SVPHSNSSGG EDPSQDRVLE
WPYSTSLGYN EEPIQGEVYN RDARYSDNGQ RENSISPYFH EPQNPDRDLR ERRSPVPPPL
PPATRHRTQD SPRSAKVSFI FGGDPPLNKP KNSGYERLLE SPEEPEHRQP YMHNHSDFRG
QDRVPFQFSG LTHVYSNIIS EEGAEEPVLR DLFYRDTTDD AEDDDDASCE EDSTGGTPVG
DERGGGGENG GDQGGGLATA AGKATFLKMS GSTDDIIDLT ALPPPEGDDG VDEDEDDTLL
QTLNLAIAAP PPGFRDSSDE DAVPEGRPLS THGNDDIPVS LIDAVPTDGE GEESGGGERR
LENAVMHTLQ ALEALSVSEQ RPPPPPPPNS NNQGAYASQG FSPESSSDSG NETNSSEMTE
ICELAATHRL SESHMRLLVA TREGYQPLLE EKTEFPVSPS TTGTIQKKPR SPTRHLQPPA
VPPRRSPLLD TSTSGQAGSD VRAHANLSST LQRPSSTTPG GKHHKKSADS SGKYNTFSTR
DGYRGEGSGI RGRLDMDQRT SFCERGESQR RHISFLEEDS AAAGHGMNSH PHDHHRNPRP
CSSTSDRLLD VVNMGDGHAD NGAAGVDQDE RLVVASLLSP TKKPRTGGSE QGSDTQSDHP
PMSRQQSVAR LCEYHLAKRI SNLQGEAHSS LQGSLCSSLD AGGSTNSSAC ATPTDSPLGP
GPFESKHHHL QRHPLSSSSS SLLRVLNYDD NKPRGNPGQS AQGKDPHPHA DPALLRKMLP
NIHAPAEPAR PSSATPSKHK ESTGTGSKRA HNDLHAKQQA HLKGLNQKEG SEAYRQLINY
LTVSQMHQGG KLHSAGMGAA VKKDTRRFIT SNPQLVEMVK NRGNTIARCP CMPSSISSPF
LSPNVVPPNA SAPMQLANKS QRSYHSATLP AKLKRSPEMH SQMLNDNLDY RSSTSERRSS
FSGLESELER SGMDPEQFLS MYKREGCMSP EGRFITGGNH EDGGNPNRHP PRSRSQPSGT
TDDWFRSEPR AKHAVRQSSH QRPSDSLCFS AAPSVSGQQL DFNTFSLGRG DHPSAFIRQT
STGPRACITS PSRNPQSPPP PPPPPPPPPP PPPPPSSLLP LPVQANTSSS NSGCQQNSIH
TMQFHPSQNH IQALTQPLRR ILWATACNGV GSSNGAPAM
//
