ID A0A3Q3KMV8_9TELE Unreviewed; 726 AA.
AC A0A3Q3KMV8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=CBFA2/RUNX1 partner transcriptional co-repressor 3 {ECO:0000313|Ensembl:ENSMAMP00000002807.1};
GN Name=CBFA2T3 {ECO:0000313|Ensembl:ENSMAMP00000002807.1};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000002807.1, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000002807.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q3KMV8; -.
DR STRING; 205130.ENSMAMP00000002807; -.
DR Ensembl; ENSMAMT00000002863.2; ENSMAMP00000002807.1; ENSMAMG00000001967.2.
DR GeneTree; ENSGT00950000183176; -.
DR InParanoid; A0A3Q3KMV8; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 6.10.250.230; -; 1.
DR Gene3D; 1.20.120.1110; TAFH/NHR1 domain; 1.
DR InterPro; IPR013289; CBFA2T1/2/3.
DR InterPro; IPR014896; NHR2.
DR InterPro; IPR037249; TAFH/NHR1_dom_sf.
DR InterPro; IPR003894; TAFH_NHR1.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR10379; MTG8 ETO EIGHT TWENTY ONE PROTEIN; 1.
DR PANTHER; PTHR10379:SF6; PROTEIN CBFA2T3; 1.
DR Pfam; PF08788; NHR2; 1.
DR Pfam; PF07531; TAFH; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR PRINTS; PR01875; ETOFAMILY.
DR SMART; SM00549; TAFH; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF158553; TAFH domain-like; 1.
DR PROSITE; PS51119; TAFH; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 149..244
FT /note="TAFH"
FT /evidence="ECO:0000259|PROSITE:PS51119"
FT DOMAIN 601..637
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 56..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 265..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 442..508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 647..726
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 540..582
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 89..142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..291
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..331
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 465..490
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..505
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 649..726
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 726 AA; 79413 MW; 319153C0F68BCE00 CRC64;
MKTNTANTFA LRVPTVTLIS HRELRDKPAA HRLQPVILGP NLATSGRYRC SEDSRVQKVG
TMPDSPADVK TQPRSTPPTM PPPPPAVSQA TNRNASFTPT TSKSMLNGSS HSPTSLNGAP
STPNGFSNGP AMSSTASLSN QQLPPACGAR QLCKLKRFLT TLQQFGTDIS PEIGERVRSL
VLGLVNSTLT IEEFHSKLHE ATNFPLRPFV IPFLKANLPL LQRELLHCAR LAKQTPAQYL
AQHEQLLLDA NASSPLDSSE IMLEMNEHGK RRTPDRTKDS SERDGLHQEH LAKRPCTISP
SQRFSPSTGL PAHPPPNGLP THPPNGLSHP PNPQVGPQHY RLEDMALAHQ YRDAYRHNEH
RDARDRHRQT AVHGARQEEV IDHRLTDREW AEEWKHLDNL LNCIMDMVEK TRRSLTVLRR
CQEADREEMN HWIRRYSDVE EMKKGGSNGQ HCLPPPPLPP PTPHHNSSSN TASSSESLPI
GTSSAAERQT GRQTEIHRDF LHRPPSGYLP EEIWRKAGTT SIPLSPAQKH LQNKQEEAVN
EVKRQAMSEL QKAVSDAERK AHEMISAERS KMERALAEAK RQASEDALTV INHQEDSSES
CWNCGRKASE TCSGCNTARY CGSFCQHKDW EKHHHVCGQG LQGLPGGSSV PLGTPSSSST
PSASSSVPPT HSESTPPGPL SLTGQSSIAG GAGSGSVSAS PKESSSSSAS RSTTPATPAL
LDATSR
//
