ID   A0A3Q3KRZ7_9TELE        Unreviewed;       958 AA.
AC   A0A3Q3KRZ7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Neuronal PAS domain protein 3 {ECO:0000313|Ensembl:ENSMAMP00000000039.2};
GN   Name=NPAS3 {ECO:0000313|Ensembl:ENSMAMP00000000039.2};
OS   Mastacembelus armatus (zig-zag eel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX   NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000000039.2, ECO:0000313|Proteomes:UP000261640};
RN   [1] {ECO:0000313|Ensembl:ENSMAMP00000000039.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q3KRZ7; -.
DR   STRING; 205130.ENSMAMP00000000039; -.
DR   Ensembl; ENSMAMT00000000039.2; ENSMAMP00000000039.2; ENSMAMG00000000032.2.
DR   GeneTree; ENSGT00940000158051; -.
DR   InParanoid; A0A3Q3KRZ7; -.
DR   Proteomes; UP000261640; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd19731; bHLH-PAS_NPAS1_PASD5; 1.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR013655; PAS_fold_3.
DR   PANTHER; PTHR23043; HYPOXIA-INDUCIBLE FACTOR 1 ALPHA; 1.
DR   PANTHER; PTHR23043:SF30; NEURONAL PAS DOMAIN-CONTAINING PROTEIN 3; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50888; BHLH; 1.
DR   PROSITE; PS50112; PAS; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261640}.
FT   DOMAIN          1..42
FT                   /note="BHLH"
FT                   /evidence="ECO:0000259|PROSITE:PS50888"
FT   DOMAIN          91..155
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          274..329
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   REGION          151..194
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          383..798
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        164..194
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        398..438
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        472..486
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        553..570
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        582..596
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        601..650
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        661..716
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        735..798
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   958 AA;  102124 MW;  16F9A486320314E7 CRC64;
     RRGKENFEFY ELAKMLPLPG AITSQLDKAS IIRLTISYLK MRDFANQGDP PWNLRIEGPP
     PNTSVKAIGN QRRRSPSVVA SEIFEPHLGS HILQSLDGFV FALNKEGRFL YISETVSIYL
     GLSQVELTGS SVFDYIHPGD HVEMAEQLGM KLPPGRGMSL SQGAVNEDGA SSASSSSHSE
     TPEPVESSSP SLLAPDNSLE RSFFIRMKST LTKRGVHIKS SGYKVIHITG RLRIRMALTH
     SRSVPNQIMG MVVVAHALPP PTINEVRIDC QMFVTRVNMD LKIVYCENRI SDYMDLTPVD
     IVGKRCYQFI HAEDVEGIRQ CHLDLMNKGQ CVTKYYRWIQ KNGGYIWIQS SATIAINAKN
     ASEKNVIWVN YVLSNPEYKD TPIDIAQLPN LPEKTSESSE TSDSESESKE NSDNENAKSE
     GKPGHQSERS EDPEADSKRQ QQSGQSHCSS EQELKRQEEG DSSSNPESQD SDDSLEPSDG
     EGEEQEEANG GGGGGGGGGG GGGGRLGRLA GLGGLGGLGA IGGLGNLGGL HIKVEHYGEG
     EEVQLHNSQT SSSEEEEEEE DDDEEEEGGM QGCDSANPGS QLQKRRKRRK LQKWDGSRSR
     RLRLSSTTPS PVSMGDTTPL VDPSQTTSAT SSHLLASSGS PHSTGAASSV LKIKTEMAEP
     INFDNDSSIW NYPPNREISR NESPYSMTSK PAAPGTHETF PSPQGGSLQV SIPDSVLTPP
     GTEGGAGGGR KPPYNGSSAP SSASSAVSLA PPSSASSADP LSPPLSASPR DKQQGTPTTS
     STSSSSSTSS SSSTSSSSLL YSGDLEALQR LQAGNVVLPL VHRVTGTLAS TSTTSPRVYT
     AGTIRYAPAD VTLAMAQGNL LPNAAMNFVD GSGFGLDPKT PMEMLYHHVH RLNMSAAAAA
     GPFVGSPTAT GGNGALGGQM STTANVFTTA EGLFSTLPFP VYSNGIHTTQ TTLERKED
//