ID A0A3Q3KWT9_9TELE Unreviewed; 1062 AA.
AC A0A3Q3KWT9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Zinc finger protein 516 {ECO:0000313|Ensembl:ENSMAMP00000001571.2};
GN Name=ZNF516 {ECO:0000313|Ensembl:ENSMAMP00000001571.2};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000001571.2, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000001571.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR AlphaFoldDB; A0A3Q3KWT9; -.
DR Ensembl; ENSMAMT00000001602.2; ENSMAMP00000001571.2; ENSMAMG00000026383.1.
DR GeneTree; ENSGT00940000160839; -.
DR InParanoid; A0A3Q3KWT9; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR45925; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR45925:SF3; ZINC FINGER PROTEIN 516; 1.
DR Pfam; PF00096; zf-C2H2; 4.
DR Pfam; PF13909; zf-H2C2_5; 1.
DR SMART; SM00355; ZnF_C2H2; 9.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 4.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 6.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 7.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 34..61
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 62..84
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 212..236
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 240..267
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 300..323
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 492..519
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1012..1039
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 87..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 437..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 509..566
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 589..623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 718..862
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 888..965
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..131
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..150
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..464
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 465..479
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..535
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..566
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..620
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 758..814
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 830..861
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 893..953
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1062 AA; 116930 MW; 7A55ACEB4CDB7B7B CRC64;
MEIQAGGQKE KLIAVKAYPE NEIEAEDDKI PGAYDCNICG RSFPFLSSLS QHMRRHTGAR
PYKCPYCDHR ASQKGNLKVH IRSHKLGTLS RHHSNEDEEG GAEEEEMSVS EGLDGGTSPT
KSSSACNRMI NGDSGEENRR KVPARTLKRE KSATDQRPYC CRLCGYKAQR EDQLLSHIEK
VHITADTEEE TTVKEEAIAE SDVIQPHSDG TFPCETCGQV FTQAWFLKSH MKKHAGILDH
CCRICGRRFR EAWFLKSHMK THNTKSRSRS KADSAEHPAT INDVAQDPDT VTSSVTSVYQ
MCSKCGNLFH SRESLRAHDK VHSLGNCRKS QSPCSLSDDE DRPAAKRRLL DYLDLQPVEE
KTLNSDEESE KMILGQRIPE LDPVCSYQAW QLATKGRVVE PVEHSYKASF GGGSMGEEAF
AGAAVVFEKE SSRYVLQGQE KRSSSRRSST GLGSHASSGD RTPESLSDSE YRPSSRQDRR
RPSQSQVSSK SNECFECGKL FRSRHQMIVH QRVHRKDGGR PSVGDKEKTA RADRWGSTSD
PESGSPSRPS TPGYGDSPPA STLGDQASEM ASSDFFIHLT PHLIRLSSGN WSHHVAKSTP
EDRRSPTPSP SSSSDRGTPN SYPKLKKALL QGLNNTASTT AYFSAPSSPL DQSMTPVDLC
VRAEGSRSIT SLTLDKKNLP IHKCSFCSHS TRYPEVLWMH QTVAHRINSS SSNVAPKWAL
KNNSKRSKDS LLSSRRRTGP PPVLEGKECP SLPPVMRTLR TQPPTYSGEV LTKNRPPSLA
ATPSPSSSST HSSSARRVPV RPGSSSSSAR QKEDQSHQSC FRPKVDIYPR GSSLSSSSSL
EKSTGTLSRP SVPSPSSATA SRMADRYLMP QEGLGFMLSS KHGLAEYSRA KGSPHHSLSN
SQSQTRANAQ RTSTITHNST TGHNYGTSQV HGGILQNSPS SSSSSSSLTS EAHGDVKQEP
ITEAQEMPSD ILSVLKNYSP HELAALYHRW GTANALLDPT GMLTSLMRQG QYFCHECGKS
FSQPSHLRTH MRSHTGKHNT AHTRGLHKIL QIPLKNHFSV SY
//
