ID A0A3Q3KXA0_9TELE Unreviewed; 887 AA.
AC A0A3Q3KXA0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=F-BAR domain only protein 2 {ECO:0000256|ARBA:ARBA00018998};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000001736.1, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000001736.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane, clathrin-coated pit
CC {ECO:0000256|ARBA:ARBA00004283}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004283}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004283}.
CC -!- SIMILARITY: Belongs to the FCHO family.
CC {ECO:0000256|ARBA:ARBA00011064}.
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DR AlphaFoldDB; A0A3Q3KXA0; -.
DR Ensembl; ENSMAMT00000001771.2; ENSMAMP00000001736.1; ENSMAMG00000001025.2.
DR GeneTree; ENSGT00940000157105; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0005905; C:clathrin-coated pit; IEA:UniProtKB-SubCell.
DR CDD; cd07673; F-BAR_FCHO2; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR036168; AP2_Mu_C_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR030122; FCHo2_F-BAR.
DR InterPro; IPR028565; MHD.
DR InterPro; IPR018808; Muniscin_C.
DR PANTHER; PTHR23065:SF8; F-BAR DOMAIN ONLY PROTEIN 2; 1.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF10291; muHD; 1.
DR SMART; SM00055; FCH; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF49447; Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS51072; MHD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640}.
FT DOMAIN 4..250
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 619..887
FT /note="MHD"
FT /evidence="ECO:0000259|PROSITE:PS51072"
FT REGION 280..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 347..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 406..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 462..568
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 87..114
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 170..208
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 281..306
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..375
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..430
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..479
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 887 AA; 97471 MW; 86F48B4C58A14F45 CRC64;
MITPYFLENF WGEKNNGFDV LYHNMKHGQI SSKELTDFIR ERSTIEEAYA RSMTKLAKSA
GNFSQLGTFA PMWEVFKTST EKLASCHMEL VRKLQELIKE VQKYVEEQAK AHKKTKEEVA
STLEAVQNIQ TISQSLQKSK EIYNAKTVEQ ERLRKEGATQ RDVDKAGVKA KKATETYKSY
VEKYATAKAE FEQKMAETAQ KFQDIEENHI LHMKEIIQSY SQSVEETHIH IGEVHYEFVR
NIENTSLESL IQKLAESKGT GKERPGPIEF EECNIAIATE GAKPRRRKPF GIPGRRKDKD
TDSTESTEVE AANTANGAPP GYYGAIDIQN ANVPQVDEDG FCIRPEINEN DAKENSFNSS
SDSEDEDEPR KFHVEIKPVQ PNNSTHQTQA TIDELKASIG NIILSPSTSG QMRRNQSRIS
GVSTLSSKAQ GPGDELAKNK VPTYELTNND LLSLDPFSPN LAAGSSSSVP SSAVQPPNRP
TTPLMAGALV PPPRPSSRPK LPTGKLTGIN EIVRPFSPPK TSSASPPPTA PLARAESSSS
LSSNASLSAG NTPTVGAEHT FAHPLSSPEP ELLSLSPSFL LSQKDDVFIA KLPTFEKQCE
TPAGTSRGPS PVTLASQDAL PIAVAFTESV NAYFKGADPT KCIVKITGDM TLSFPVGIIK
VFTTNPSPAV LTFKLKNTSR LEQILPNQQL LYSDPSQSDS NSKDFWFNMQ ALTSYLRKAL
DQNPAASYYN VDILKYQVLS DGIHSTPLNL AVYWKCTPST TDLRLDYRYN PDSMASPGPL
TNVQILVPVD GGVTNMQSLP SSVWNSEQNK CLWKLSDISE KSEIEGAASL RAKFDLSNGP
STPSTLAVQF MNEGTTLSGV DMELQGTGYR ISLSKKRFAT GRYMADC
//
