ID A0A3Q3L2E7_9TELE Unreviewed; 643 AA.
AC A0A3Q3L2E7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=RAP1 GTPase activating protein 2 {ECO:0000313|Ensembl:ENSMAMP00000003716.2};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000003716.2, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000003716.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q3L2E7; -.
DR Ensembl; ENSMAMT00000003801.2; ENSMAMP00000003716.2; ENSMAMG00000002443.2.
DR GeneTree; ENSGT00940000165230; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 6.10.140.210; -; 1.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR15711:SF17; RAP1 GTPASE-ACTIVATING PROTEIN 2; 1.
DR Pfam; PF21022; Rap-GAP_dimer; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 585..607
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 162..378
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT REGION 33..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 389..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 446..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 519..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..469
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 519..534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 549..573
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 643 AA; 70817 MW; 96210ABC7454C8C7 CRC64;
TLIDVLEKGG PYPQVILPQF GGYWIEDVEA QAGTPSSSES SFCEEEEGGE GMSPGGGHNY
RLECNSTARA YRKHFLGKEH MNYYCTGSSI GNLIMSLKHE EAEAQEFLRI MLRSRTKTVH
DRISLAGINQ LPSVPQIAKL FCDDATGLKF NPVLYPRGSQ LIVAYDEHEV NNTFKFGVIY
QKFGQTSEEE LFGNNEETPA FKEFLSILGN NTELQDFKGF RGGLDVSHGQ TGSESVYTVF
RQREIMFHVS TKLPFTEGDV QQLQRKRHIG NDIVAAVFQE EPTPFVPDMI ASNFLHAYVL
VQAENPCTEH TTYKVSVTAR EDVPPFGPPL PNPAVFKKGP EFRDFLLTKL INAENACYKS
DKFAKLEGRT RAALLDNLHD ELHRQSQATL GLGQPGEEDK LENGGHGGLL ESFKRAMRVR
SHSMETMVGS HRHRSPGVGG GVPASLSGGG LPQSTSECTK STFTPPALSA KSPLKSPVKR
RSGLFPRLHS MFSCFQVTSL MCCFVCSDQK SAETCPLSQE VRSETSSNPS SPEICPNKDR
PFIKMKESSS GRPNISRSSS STSSFSSTTG ETEALEELEP VSATLTMFFT VMSISFLLFP
FPSCLIADGK NKTSPRTNLK FRFDKMSHSS TSTVGHLVIS GSL
//
