ID A0A3Q3L483_9TELE Unreviewed; 451 AA.
AC A0A3Q3L483;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Growth differentiation factor 10b {ECO:0000313|Ensembl:ENSMAMP00000004386.2};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000004386.2, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000004386.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR AlphaFoldDB; A0A3Q3L483; -.
DR STRING; 205130.ENSMAMP00000004386; -.
DR Ensembl; ENSMAMT00000004493.2; ENSMAMP00000004386.2; ENSMAMG00000002975.2.
DR GeneTree; ENSGT00940000157214; -.
DR InParanoid; A0A3Q3L483; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd19394; TGF_beta_GDF10; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF265; BMP3B; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..451
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030080994"
FT DOMAIN 338..451
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 122..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..136
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 451 AA; 51046 MW; D9E570016B888EE3 CRC64;
MINRVFHILH LFLILESIWG KLVSEDLIRA VRQGAEAAPA VEQRVFAHDS ANRDMVSISM
FKVYEKYSKE PQSQRDGNTV RSFKAVPRVL HGKEMFQFNL SSIQDSEIIL FASFHFLHKR
HHQRPWRSRR PRHPSGSFQH PHSPSTQLLF HGSSTNSAFA TLLGNITLAP FKKGSWQTRD
ITAVVKHARD VKELVVTVEF DIGFGVARVN QRSPQGQERL SPANLPYILV YADDQAIDEP
NSVAMSLQRY GPFPVGDDAS SSASASRIRR ELHLQIQTND IPEVQFNTLK NHELWQNTYF
PAKAKAAVKS GRKQGQENSE GLSKPQVLSF DERTMKKARR RQWSEPRVCA RRYLRVDFAD
IGWSEWVLAP KSFDAYYCAG TCGFPIPKVL RPSNHATIQS IVRAVGIIPG VPEPCCVPEK
MSPLSVLFLD PNRNMVLKVY PGMSVDTCAC R
//
