ID   A0A3Q3L4A0_9TELE        Unreviewed;       252 AA.
AC   A0A3Q3L4A0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Neuferricin {ECO:0000256|ARBA:ARBA00039568};
DE   AltName: Full=Cytochrome b5 domain-containing protein 2 {ECO:0000256|ARBA:ARBA00042241};
OS   Mastacembelus armatus (zig-zag eel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX   NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000008272.1, ECO:0000313|Proteomes:UP000261640};
RN   [1] {ECO:0000313|Ensembl:ENSMAMP00000008272.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Heme-binding protein which promotes neuronal but not
CC       astrocyte differentiation. {ECO:0000256|ARBA:ARBA00037690}.
CC   -!- SIMILARITY: Belongs to the cytochrome b5 family. MAPR subfamily.
CC       {ECO:0000256|ARBA:ARBA00038357}.
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DR   AlphaFoldDB; A0A3Q3L4A0; -.
DR   STRING; 205130.ENSMAMP00000008272; -.
DR   Ensembl; ENSMAMT00000008493.2; ENSMAMP00000008272.1; ENSMAMG00000005622.2.
DR   GeneTree; ENSGT00940000160156; -.
DR   InParanoid; A0A3Q3L4A0; -.
DR   Proteomes; UP000261640; Unplaced.
DR   Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR   InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR   InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR   PANTHER; PTHR10281; MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED; 1.
DR   PANTHER; PTHR10281:SF4; NEUFERRICIN; 1.
DR   Pfam; PF00173; Cyt-b5; 1.
DR   SMART; SM01117; Cyt-b5; 1.
DR   SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           16..252
FT                   /note="Neuferricin"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018675590"
FT   DOMAIN          40..136
FT                   /note="Cytochrome b5 heme-binding"
FT                   /evidence="ECO:0000259|SMART:SM01117"
SQ   SEQUENCE   252 AA;  27525 MW;  34A6CBE1898ACEF3 CRC64;
     MLGYVLVAFL SISLALLFVP REWSPKFASD PSQETPERLL SRSDLSRYDG EDGSRGLYLA
     ILGHVFDVHK GHKHYGPGGA YHFMAGKDAS LAFITGDFTE KGLTDDVSSL SPLQVLALYD
     WLAFYQREYQ SVGFLIGRFY SETGQPTQAL LQVRASLAEG RRIKTQSEAE SQRFPACNSE
     WSTTKGGRVW CSTKSGGVVR EWAGVPRKLF SPGSSGARCV CVADPSAAEE DPNLQQYKGC
     PPHAESCSVG GK
//