ID A0A3Q3LDR7_9TELE Unreviewed; 1515 AA.
AC A0A3Q3LDR7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Adhesion G protein-coupled receptor L3-like {ECO:0000313|Ensembl:ENSMAMP00000007564.2};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000007564.2, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000007564.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR Ensembl; ENSMAMT00000007772.2; ENSMAMP00000007564.2; ENSMAMG00000005041.2.
DR GeneTree; ENSGT00940000155527; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd22846; Gal_Rha_Lectin_LPHN3; 1.
DR Gene3D; 1.25.40.610; -; 1.
DR Gene3D; 2.60.120.740; -; 1.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 4.10.1240.10; GPCR, family 2, extracellular hormone receptor domain; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR032471; GAIN_dom_N.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR036445; GPCR_2_extracell_dom_sf.
DR InterPro; IPR001879; GPCR_2_extracellular_dom.
DR InterPro; IPR003924; GPCR_2_latrophilin.
DR InterPro; IPR003334; GPCR_2_latrophilin_rcpt_C.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR017983; GPCR_2_secretin-like_CS.
DR InterPro; IPR000203; GPS.
DR InterPro; IPR000922; Lectin_gal-bd_dom.
DR InterPro; IPR043159; Lectin_gal-bd_sf.
DR InterPro; IPR003112; Olfac-like_dom.
DR PANTHER; PTHR12011:SF60; ADHESION G PROTEIN-COUPLED RECEPTOR L3; 1.
DR PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF16489; GAIN; 1.
DR Pfam; PF02140; Gal_Lectin; 1.
DR Pfam; PF01825; GPS; 1.
DR Pfam; PF02793; HRM; 1.
DR Pfam; PF02354; Latrophilin; 2.
DR Pfam; PF02191; OLF; 1.
DR PRINTS; PR00249; GPCRSECRETIN.
DR PRINTS; PR01444; LATROPHILIN.
DR SMART; SM00303; GPS; 1.
DR SMART; SM00008; HormR; 1.
DR SMART; SM00284; OLF; 1.
DR PROSITE; PS00650; G_PROTEIN_RECEP_F2_2; 1.
DR PROSITE; PS50227; G_PROTEIN_RECEP_F2_3; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
DR PROSITE; PS51132; OLF; 1.
DR PROSITE; PS50228; SUEL_LECTIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00446};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 925..948
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 960..978
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 984..1006
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1027..1045
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1065..1085
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1097..1124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1130..1153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 97..186
FT /note="SUEL-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50228"
FT DOMAIN 191..450
FT /note="Olfactomedin-like"
FT /evidence="ECO:0000259|PROSITE:PS51132"
FT DOMAIN 544..601
FT /note="G-protein coupled receptors family 2 profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50227"
FT DOMAIN 923..1154
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 1174..1195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1404..1466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1483..1515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1404..1423
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 192..374
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00446"
SQ SEQUENCE 1515 AA; 169545 MW; 7B66CF0833297E4D CRC64;
MHEREPPQTC VGVCVRAPVS RRGKTATLGP PPLGPTSPPA RFGSAVNSRI LPDRLSALAR
SNKHLLTPCF LPVCSLSEAH SFSRAPIPMA VVRRELSCES YPIELRCPGT DVIMIESANY
GRTDDKICDA DPAQMENTRC YLPDAYKIMS QRCNNRTQCA VVAGPDVFPD PCPGTYKYLE
VQYECVPYIF LCPGLLRRVY QSEHLFESDH QSGAWCKDPL QASDKIYYMP WTPYRTDTLT
EYSSKEDFIA GRPTTTYKLP HRVDGTGFVV YDGALFFNKE RTRNIVKFDL RTRIKSGEAI
IANANYHDTS PYRWGGKSDI DLAVDENGLW VIYATEQNNG RIVISQLNPY TLRVEGTWDT
AYDKRSASNA FMICGILYVV KSVYEDDDNE ATGNKIDYIY NTELSKDGFL DIPFPNSYQY
IAAVDYNPRD NLLYVWNNYH VVKYSLDFGA LDNRLETSSS VMIYMDTTTT TMKTTTRPTT
VTMTTTTAKT TTTNMPATTA AIAPWPRTTS TVVALVQTMV EGLVPEDEER APPSSKLPNI
RVEYCNPLMM MDISWPKTKQ GIVAKMPCPA GTTGVATYMC MGPEGYWDPQ GPDISNCTSP
WVNLISQKLK AGETAAVIAR ELAEQTKSNL QAGDITYTVK AMVQLVELLD VQLRNLTPGG
KDSAARSLNK LQKRERSCRF YVQAMVETVN NLLQPQAQAA WRELSTSEQL RAATMLLDTV
EQGAFVLADN LLKTDIVQEN TDNIQLEVAR MSTDGNLPDL KFPQIGGQGN SIHLSANTLK
QHGRNGEIRI AFVLYKHIGV YLSTENASMK LGSDAMATNY SVIVNSPVIT AAINKDSNKV
YLSDPVIFTI RHLQQSEENF NPNCSFWNYN KRTMTGYWST QDCRLLGTNK THTTCSCTHL
TNFAVLMAHV DVKNTDPVHD MLLDVITWVG ILLSLVCLLI SLFTFCFFRG LQSDRNTIHK
NLCISLFIAE SLFLVGINRG DQPIACAVFA ALLHFFFLAA FTWMFLEGVQ LYIMLVEVFE
SEHSRRRYFY LVGYGVPALI VAVSAAVDYR SYGTDRVCWL RLDTYFIWSF IGPATLIIML
NVIFLEHSDR SDMYVLTCFR SWVIGAIALL CLLGLTWAFG LMYVNESTVV MAYLFTIFNS
LQGMFIFIFH CVLQKKVRKE YGKCLRTHCC SGKSVDSSMG SGKGTTSRAP GRYSTGSQSR
IRRMWNDTVR KQSESSFMTG DINSSASLNR GTWSHKGILN NARDTSVMDT LPLNGNHGNS
YSIASAEYMS DCVQIIDRGY NHKETTLEKK ILKELTSNYI PSYLNNSHER SSEHNRNLMN
KLVNNVIGMG MNVALSLDDH STFGPHHDEG LGLELIREES NAPLLPQRPP PSLQAVDNLH
NHLHQSVRIP QENSESFFPL LTNEHTENEG SSPTHNHQRD SLYTSMPMLP GLPDVSAESA
DSSKDGGDTK SPEASSDDVY YKSMPNLGSR NHLHQLHSYY QLGRGSSDGF IVPPNKEDVS
PEEASQEPPH LVTSL
//
