ID A0A3Q3LHE9_9TELE Unreviewed; 585 AA.
AC A0A3Q3LHE9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Insulin-like growth factor 2 mRNA binding protein 3 {ECO:0000313|Ensembl:ENSMAMP00000012652.1};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000012652.1, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000012652.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RRM IMP/VICKZ family.
CC {ECO:0000256|ARBA:ARBA00009094}.
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DR AlphaFoldDB; A0A3Q3LHE9; -.
DR STRING; 205130.ENSMAMP00000012652; -.
DR Ensembl; ENSMAMT00000012985.2; ENSMAMP00000012652.1; ENSMAMG00000008545.2.
DR GeneTree; ENSGT00940000154957; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.310.210; -; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR10288:SF158; INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 3; 1.
DR PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR Pfam; PF00013; KH_1; 4.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00322; KH; 4.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 4.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50084; KH_TYPE_1; 4.
DR PROSITE; PS50102; RRM; 1.
PE 3: Inferred from homology;
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 2..75
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 161..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 564..585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 585 AA; 63651 MW; 153264ACA7D5EEB7 CRC64;
MNKLYIGNVS AEASEKDFET IFEQWKIPHS GPFLVKTGYA FVDCPDEKAA MKAIDVLSGK
VELHGKVLEV EHSVPKRQRS CKLQIRNIPP HMQWEVSANR LLTASRVGHH GTAQLGSYLV
ASGVTLPPSG FQLSIAMEKL NGFMMENYAL KVSYIPDETA APEGPSAGGR RGFNARGPPR
SSSPGLGARP KVQSDIPLRM LVPTQFVGAI IGKEGATIRN ITKQTHSKID IHRKENAGAA
EKPITIHSTP EGCSNACRTI MEIMQKEALD TKFTEEIPLK ILAHNNFVGR LIGKEGRNLK
KIEQDTETKI TISPLQDLTL YNPERTITVK GSIEACSRAE EEVMKKIRES YESDMAAMNL
QSNLIPGLNL NALGLFPSGA PGMGPSMSNV PPPGAHGGCS SFGGHPESET VHLFIPALAV
GAIIGKQGQH IKQLSHFAGA SIKIAPAEGM DAKQRMVIII GPPEAQFKAQ CRIFGKLKEE
NFFGPKEEVK LEAHIKVPSF AAGRVIGKGG KTVNELQNLT CAEVVVPRDQ TPDENDQVIV
KISGHFFACQ LAQRKIQEIL AQVRRQQQQQ AKPASGAQPP LPRRK
//
