ID   A0A3Q3LI04_9LABR        Unreviewed;       905 AA.
AC   A0A3Q3LI04;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Periodic tryptophan protein 2 homolog {ECO:0000313|Ensembl:ENSLBEP00000008370.1};
OS   Labrus bergylta (ballan wrasse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Labriformes; Labridae; Labrus.
OX   NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000008370.1, ECO:0000313|Proteomes:UP000261660};
RN   [1] {ECO:0000313|Ensembl:ENSLBEP00000008370.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604}.
CC   -!- SIMILARITY: Belongs to the WD repeat PWP2 family.
CC       {ECO:0000256|ARBA:ARBA00010226}.
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DR   AlphaFoldDB; A0A3Q3LI04; -.
DR   STRING; 56723.ENSLBEP00000008370; -.
DR   Ensembl; ENSLBET00000008792.1; ENSLBEP00000008370.1; ENSLBEG00000006388.1.
DR   GeneTree; ENSGT00550000074981; -.
DR   InParanoid; A0A3Q3LI04; -.
DR   Proteomes; UP000261660; Unplaced.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProt.
DR   CDD; cd00200; WD40; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR027145; PWP2.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR007148; SSU_processome_Utp12.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR19858:SF0; PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG-RELATED; 1.
DR   PANTHER; PTHR19858; WD40 REPEAT PROTEIN; 1.
DR   Pfam; PF04003; Utp12; 1.
DR   Pfam; PF00400; WD40; 4.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 12.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 3.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261660};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   REPEAT          184..216
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          370..411
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          484..517
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   DOMAIN          757..860
FT                   /note="Small-subunit processome Utp12"
FT                   /evidence="ECO:0000259|Pfam:PF04003"
FT   REGION          225..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          870..905
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        875..892
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   905 AA;  101058 MW;  030A0BBAA54A473D CRC64;
     MKFAYRFSNL LGAVYRQGNL NFSKDGNAVI SPVGNRVSVF DLKNNTSETL PISTTKNITC
     VGLSPDGNIA IVVDEDGAAL LVSLITRAIL HHFHFHKPVN SIRFSPDGRR FVVTKENVAL
     MYHAPGKQRE FNAFVLDKSY YGPYDETTCI DWTDDSKCFV VGSKDMSTWV FGAERWANLI
     YYSLGGHKDV IVGCFFEKDS LDLYTVSQDG TLCVWESDTE LDGLILPKKS KPQPPGPGEE
     EEGEDEVERV EGEEGEVIRG KVEAPKEKKT RNVRFKHRSK HFFNKEGDFN NLTAAAYHKP
     THILITGFAS GIFHLHELPE FNLIHSLSIS DQRISSVSIN CSGDWIGFGC SGMGQLLVWE
     WQSESYVFKQ QGHFNNMASL AYSPDGQYIV TGGDDGKVKV WNTNSGLCFV TFTEHTSSVT
     NVTFTSSAFD LHRYRNFRTF TSPRPAQFSS LAVDVSGELV SAGAQDSFEI FLWSMQTGRL
     LEVLGGHEGP VSCLCFSPVQ SILASASWDR TIRLWDMLDS WQVKETLPLT SDALSVTYRP
     DGQELAVATL NGEICFWNPQ SAAQTGSVSG RHDLETGRKE TDKITAKQSA KGKSFTSLCY
     SADGESILAG GQSKFVCIYN IREQMLMKKF EISCNLSFDA MEEFLDRRKM TEFGSLALVD
     EGAGDGDGVN ISLPGVRRGD MSSRHFKPEI RVSSLRFSPT GRSWAATTTE GLLVYSLDGS
     LVFDPYDLDL DVTPASIRKQ LRLQEWTSAI ILAFRLNEKA LKQEVLESVP HDQIRVVCGS
     LPDIYVEKLL SFVAACLEKS GHLQFYMTWA QNLLMLHGQK LKNRSGAILP TLQALQKSIQ
     RHFEDLSKLC DFNVFNIRYA VALSKQRGMK RAAEDDEEEE EEEEEDRELS EEMSEASLDG
     ADMIL
//