ID A0A3Q3LRH3_9TELE Unreviewed; 1087 AA.
AC A0A3Q3LRH3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like {ECO:0000313|Ensembl:ENSMAMP00000016858.2};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000016858.2, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000016858.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR AlphaFoldDB; A0A3Q3LRH3; -.
DR Ensembl; ENSMAMT00000017311.2; ENSMAMP00000016858.2; ENSMAMG00000011398.2.
DR GeneTree; ENSGT00940000159303; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR GO; GO:0022008; P:neurogenesis; IEA:UniProt.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF65; SEMAPHORIN-6D; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..1087
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030081220"
FT TRANSMEM 650..673
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 34..507
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT REGION 781..872
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 916..965
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1023..1087
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 789..810
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 839..872
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 948..965
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1034..1049
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1087 AA; 119656 MW; 2E65DC457BF0E91E CRC64;
MGQRAALLLS ELLLLLLLLT ASRTLLAVSF PEDIVPLDVV DAHFSRRYPV FRGRPSGNES
QHRLDFQLMT KIQDTLFIIP HTNIVSHSLK LTWRSGQADR EMCAVKGKHR DECHNFIKVL
VPRNDDLVFI CGTNGFNPMC RYYRLDNLEL DGEEINGLAR CPFDSKQTNV ALFAEGKLYS
ATVADFQASD SVIYRSMGDG SALRTIKYDS KWLKEPHFLH AAEYGNYVYF FYREIAVEHS
NLGKVVYSRV ARICKNDVGG SQRVLEKHWT SFVKARLNCS VPGESFFYFD VLQSITDIIN
INGVPSVVGV FTTQMNSIPG SAVCAFSMAD IEKVFQGRFK EQKTPDSVWT PFPEEKLPKP
RPGCCAGQGP AAAFKSSIEF PDDTLQFIKS HPLMDTAVPS IGDEPWFTKT RVRYRLTALA
VDNEAGPHKN YTVVFIGAES GVVLKVLAKT TAVSLNDSLL LEEIDVFNRA KCLSNHEDDK
RVLSLHVDKD THSLYVSFSS CVIRIPLSRC ERHSSCHKSC IALRDPYCGW KPHGVCERIQ
PGVLTGYEQD VEFGNTSQLG DCHGMNLISI PYMEFSSAPV TVQPSGPIHP PVLIPTQSPS
SGPGPELYGS GFVLQDDPAT SHSLDSIPGG QEGVWDIQAG ETNQMVHMNI LITCVFAAFL
MGALLAGLIV FCYRDSFLRK PRHVHKDAES APSCSDSTGS FVKLNGLFDS PVKEYQTNIE
SPKLYTNLLS NVKDLNTPNG DTKTMILRDG CQAPELAALP TPESTPVLQQ KGLQPIKNQW
DRAHGKVSGP NKESNSSAKS PQYLLSSPAP PNSTPHHPHL GHSHIPSAVV LPNATHDHPN
LENGDETLPH SSEKKLKNPD SKGSKKDQKR SVDARNTLND LLKHLNDSVA NPKAILQEGS
VPRPRQQLTL EPMQELTELP PKVPSREASL YSPSSSLPRH SPTKRVDVPM PTTPTTPTGS
LSMGGTLERQ RGGYQLHRSA SHRHSLSTSP NGVTMGVSVS RQHSMNRGGY MPPTPPSRLD
SHGGVMGTGM HSAHPPSVSR QSSYSGHGSL PRTGLKRTPS LKPDVPPKPN GFSPQTPQMR
VVNKYSY
//
