ID   A0A3Q3LSH5_9LABR        Unreviewed;       551 AA.
AC   A0A3Q3LSH5;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=GDNF family receptor alpha 4b {ECO:0000313|Ensembl:ENSLBEP00000011465.1};
OS   Labrus bergylta (ballan wrasse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Labriformes; Labridae; Labrus.
OX   NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000011465.1, ECO:0000313|Proteomes:UP000261660};
RN   [1] {ECO:0000313|Ensembl:ENSLBEP00000011465.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the GDNFR family.
CC       {ECO:0000256|ARBA:ARBA00005961}.
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DR   AlphaFoldDB; A0A3Q3LSH5; -.
DR   STRING; 56723.ENSLBEP00000011465; -.
DR   Ensembl; ENSLBET00000012056.1; ENSLBEP00000011465.1; ENSLBEG00000008788.1.
DR   GeneTree; ENSGT00940000160491; -.
DR   InParanoid; A0A3Q3LSH5; -.
DR   Proteomes; UP000261660; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   Gene3D; 1.10.220.110; GDNF binding domain; 1.
DR   InterPro; IPR016017; GDNF/GAS1.
DR   InterPro; IPR037193; GDNF_alpha.
DR   InterPro; IPR003438; GDNF_rcpt.
DR   PANTHER; PTHR10269:SF2; GDNF FAMILY RECEPTOR ALPHA-4; 1.
DR   PANTHER; PTHR10269; GDNF RECEPTOR ALPHA; 1.
DR   Pfam; PF02351; GDNF; 3.
DR   PRINTS; PR01316; GDNFRECEPTOR.
DR   SMART; SM00907; GDNF; 3.
DR   SUPFAM; SSF110035; GDNF receptor-like; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261660};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           26..551
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018738291"
FT   DOMAIN          29..108
FT                   /note="GDNF/GAS1"
FT                   /evidence="ECO:0000259|SMART:SM00907"
FT   DOMAIN          148..228
FT                   /note="GDNF/GAS1"
FT                   /evidence="ECO:0000259|SMART:SM00907"
FT   DOMAIN          238..332
FT                   /note="GDNF/GAS1"
FT                   /evidence="ECO:0000259|SMART:SM00907"
SQ   SEQUENCE   551 AA;  58791 MW;  FB399AFBF25AABD4 CRC64;
     MLRPLIRLFS VLIGSLTALL EVIQAGRDCL LAGDSCSGNE TCSPRLRTLR QCVAGNGSVK
     LGPGARSQCA NAVSALLSSP LQGCQCKRGM KKEKNCLSIY WSLHQSIMHG LNLVESFPYE
     PVHREYDYVR LASIAAESKV GMTTVNRCLD AAKACNVDDL CQKLRTEYVS ACIKPTAKSG
     LCNRPKCNKA LRRFFDRVPA DYTHELLFCP CTDTACAERR RQTIVPSCSY ESGDKPNCIT
     QMGICNADYV CRSRLAQFQY DCEPSETSAN GCSRKDHGAC LLAYTGLIGS TMTPNYVDNS
     TSSVAPWCTC SSSGSRKDEC ETFLGHFTNN ICLQNVEHLL TFSLSPSSVS LSSLSSLSPL
     SLPLLPLSSL SSLSLPSLPL SPLSLSPSLS SLPPSLSLSL LSLSSPLSLS SLSLSLALPP
     SLSLSLSLLS LSLSLSLSSL SLSLLFSLLS SLSLSLLLSL SSLSLSSLSF SLPLPLSLSL
     ALLPLSFSLS SLSPPLLSLS LLLSPCSPFS LSLSSLSPLY LSLSLPFSPR SPSLPLSLLS
     LPLFPPLFLS L
//