ID A0A3Q3LX00_9LABR Unreviewed; 802 AA.
AC A0A3Q3LX00;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};
OS Labrus bergylta (ballan wrasse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrus.
OX NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000012955.1, ECO:0000313|Proteomes:UP000261660};
RN [1] {ECO:0000313|Ensembl:ENSLBEP00000012955.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the OSBP family.
CC {ECO:0000256|RuleBase:RU003844}.
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DR AlphaFoldDB; A0A3Q3LX00; -.
DR Ensembl; ENSLBET00000013638.1; ENSLBEP00000012955.1; ENSLBEG00000009796.1.
DR GeneTree; ENSGT00940000155957; -.
DR Proteomes; UP000261660; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd13287; PH_ORP3_ORP6_ORP7; 1.
DR Gene3D; 2.40.160.120; -; 1.
DR Gene3D; 3.30.70.3490; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR037239; OSBP_sf.
DR InterPro; IPR000648; Oxysterol-bd.
DR InterPro; IPR018494; Oxysterol-bd_CS.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041680; PH_8.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10972; OXYSTEROL-BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR10972:SF15; OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 3; 1.
DR Pfam; PF01237; Oxysterol_BP; 1.
DR Pfam; PF15409; PH_8; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS01013; OSBP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055,
KW ECO:0000256|RuleBase:RU003845};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000261660};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003845}.
FT DOMAIN 51..146
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 386..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 733..760
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 802 AA; 90942 MW; C7D7971EEF4ED9CD CRC64;
MGSEERSSAM SQKISSVSRS NSSSSSKHDS RQDSWEIVEG LRGGFSSVLE PQKQEGYLLK
KRKWPMKGWH KRYFFLDKGI LKYGKCSTDI EKGKLHGCID VGLSVMAIKK KSKCIDLDAE
ENIYHLKIKS PELFDEWVSK LRHHRLYRQN EIAMYSNEKS FYYPHYPSPI SPGMPESASV
RKVYLSGAVA LSCSSQAKVT AWLQSSNDMD KCSKDLSVCE AHLLELNHLL QSMEILHRTY
SAPSIQALQV PSCISSGSIR LHASNPNLSS AAMVNDKVDT ESLDSTFDVA KLQEDFCRVA
TNLHATMTSA LSSLTSERER LKQCLDHETC PPTSPQVVGL KNALSSVTSV DESHPLVHQV
SNESRASITE SLSEFFDAHE VLLSASSSEN EASEDDSNIS DISDNISIDN FSNETESERP
NSGLCQRRSC LPSPCPNNST ISLWNILRNN IGKDLSKVAM PVQLNEPLNT LQRLCEELEY
SELLDRAANT HDPFERMVYI ATFVVSGYAS SYYRTGGKPF NPILGETYEC DRPDKGFRFV
AEQVSHHPPI SACHAESKNF IYWQDVRCKN KFWGKSMEIV PVGTIHVALP GTGDHYEWNK
VTSCIHNILS GQRWIEHYGE ISIRNSASDI CQCKITFVKA KYWNSSVNEI EGTITDNKGK
VTRRLFGKWH ESVFCGDPPS ATCVWRANAM PVDHEQYFGF TKFAIELNEL DPSLKQLLPP
TDTRLRVDQR LLEEGNLEAA EEHKQRIEQL QRERRRLLEE SNSVHQPKFF RKSKDDTWVS
NNTYWELRKE TNFNHMESPT LW
//
