ID A0A3Q3LXS6_9TELE Unreviewed; 1394 AA.
AC A0A3Q3LXS6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Par-3 family cell polarity regulator {ECO:0000313|Ensembl:ENSMAMP00000017962.2};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000017962.2, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000017962.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endomembrane system
CC {ECO:0000256|ARBA:ARBA00004308}.
CC -!- SIMILARITY: Belongs to the PAR3 family.
CC {ECO:0000256|ARBA:ARBA00005358}.
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DR Ensembl; ENSMAMT00000018436.2; ENSMAMP00000017962.2; ENSMAMG00000011996.2.
DR GeneTree; ENSGT00950000183214; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.
DR CDD; cd00992; PDZ_signaling; 3.
DR Gene3D; 2.30.42.10; -; 3.
DR InterPro; IPR021922; Par3/HAL_N.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR16484:SF10; PARTITIONING DEFECTIVE 3 HOMOLOG; 1.
DR PANTHER; PTHR16484; PARTITIONING DEFECTIVE 3 RELATED; 1.
DR Pfam; PF12053; Par3_HAL_N_term; 1.
DR Pfam; PF00595; PDZ; 3.
DR SMART; SM00228; PDZ; 3.
DR SUPFAM; SSF50156; PDZ domain-like; 3.
DR PROSITE; PS50106; PDZ; 3.
PE 3: Inferred from homology;
KW Cell junction {ECO:0000256|ARBA:ARBA00022427};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Tight junction {ECO:0000256|ARBA:ARBA00022427}.
FT DOMAIN 279..355
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 474..548
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 602..677
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 81..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 383..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 774..844
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 871..894
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 939..1394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..465
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 781..795
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 807..821
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 874..894
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 968..990
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 991..1116
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1133..1153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1154..1179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1211..1240
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1252..1277
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1291..1307
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1322..1338
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1339..1353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1394 AA; 154556 MW; 48EB5046AEAC25A1 CRC64;
MKVTVCFGRT RVVVPCGDGN IKVRTLIQQA VMRYKKAIAK DASYWLQVHR LEHGDGGILD
LDDVLCDVAD DKDRLIAIYD EQEPHHGGDG TSASSTGTQS PDLFAADLSA GSGASAFQPY
QAASEIEVTP SALRTNMPLH VRRSSDPALM TVNGPFVSGE SRVQTEEQPS RKNPTRWSTT
AGFLKARHSS GTNSLERKGK GMDTYRSLPR DAGTWASQRE FQRETARSSL SANHPMVDHW
LMRQEQEEEA REEENGRIEP VGRADSCMDH TPVKSLEDIV RLVEVSNDGG PLGIHVVPFS
GRDRRTLGLL VKRLEKGGKA EQEGLFQEND CIVRINNGDL RNIRFEQAQN MFRQAMRSPV
IMFHVVPSTM KVHYEQLSQA ERNPAYTSGR FSPDSLTGST VSGMDQTPQR VSRHGAQTHL
HSQTHADATD GYTPLTHPAV TAAKPPTGHT HSPQRGLSSA STGGYTKKVG RRLNIQLKKG
PEGLGFSITS RDVPIGGSAP IYVKNILPRG AAIQDGRLKA GDRLLEVNGV DLNGRTQEEV
VSLLRATPMG GAVGLLVLRQ EDAFLPREAN AEPQMQSPRG LKTEDDDLVL TPDGTREFLT
FEIPLSDSGS AGLGVSVKGN RSKENHADLG IFVKSIINGG AACKDGRLRV NDQLIAVNGE
SLLGKTNQDA METLRKSMST EGNKRGMIQL IVARRVAKRN EATPGSPLGP QQTVNTSLDD
HERRISHSLY GGLEGLDDNL KPRQGMMPRT IGNYQLSPTV NMPQDDTVII EDDRPPLLPP
HLSDQSSSSS HDDVGFTADM TPPWAKEMPN QNDSSMSPDE NHPDGVFQRE GFGRQSMSEK
RTKQFGDATQ LDIIKTRKSK SMDLVADEIN LTPRPETSKG SSTKDVGPSL GLKKSSSLES
LQTAVAEVTL NGDLPFHRPR PRIIRGRGCN ESFRAAIDKS YDRPAATEDD DEGMETLEED
TEESSRSGRD SVSTVADQTP LSGTEKTLVN GTNRTKEEKK KDKDKGGKEK KKQDGGKEKD
KGKAKKGMLK GLGDMFRFGK HRKDERPGEK MDRKGSSKWR PEEMQASEEE TMKMRMEQER
IQAKTRELRE RQARERDYAE ILDISRTSER SSEEEHPYAG INPLNSSVDS GHSRPHSPRD
DYPHMHPHHQ HQHSDSLYTQ VSKARNDRPP SADSNRLAPS NHDRIQRLRQ EFQQAQNVQD
DPDDRRRTYS FEQPWSNASS NGPGGYSQPG RHSVSVEVQM QRQRQEERDS FAQAQRQYSS
LPRQPRKNPS SISQDSWDKA YPPGEGFQTA KDNPRYSSYQ GSRNGYPGGS GVNARVLLEA
QELLRQEQRR REQEAKGKLM QESTSNSSYE GYSTGHLKDP ASPKGPYRQD VPPSPSQLAR
LNRLGSEKGR LFYS
//
