ID   A0A3Q3M2J5_9TELE        Unreviewed;       766 AA.
AC   A0A3Q3M2J5;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Cullin-3-like {ECO:0000313|Ensembl:ENSMAMP00000016836.2};
OS   Mastacembelus armatus (zig-zag eel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX   NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000016836.2, ECO:0000313|Proteomes:UP000261640};
RN   [1] {ECO:0000313|Ensembl:ENSMAMP00000016836.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   AlphaFoldDB; A0A3Q3M2J5; -.
DR   Ensembl; ENSMAMT00000017287.2; ENSMAMP00000016836.2; ENSMAMG00000011362.2.
DR   GeneTree; ENSGT00940000155066; -.
DR   InParanoid; A0A3Q3M2J5; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000261640; Unplaced.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF168; CULLIN-3; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          381..633
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          675..696
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        680..696
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   766 AA;  88646 MW;  B59F9B80D7604D67 CRC64;
     MSNLKGGTKK DTKMRIRAFP MTMDEKYVNN IWDLLKNAIQ EIQRKNNSGL SFEELYRNAY
     TMVLHKHGEK LYTGLREVVT EHLINKVRED VLNSLNNNFL QTLNQAWNDH QTAMVMIRDI
     LMYMDRVYVQ QNNVENVYNL GLIIFRDQVV RYGCIRDHLR QTLLDMIARE RKGEVVDRGA
     IRNACQMLMI LGLDGRSVYE EDFEGPFLDM SAEFFQMESQ KFLAENSASV YIKKVEARIN
     EEIERVMHCL DKTTEEPIVK VVERELISKH MKTIVEMENS GLVHMLKNGK TEDLACMYKL
     FSRVPNGLKT MCECMSSYLR EQGKALVSEE GEGKNPVDYI QGLLDLKTRF DRFLLESFNN
     DRLFKQTIAG DFEYFLNLNS RSPEYLSLFI DDKLKKGVKG LTEQEVESIL DKAMVLFRFM
     QEKDVFERYY KQHLGRRLLS NKSVSDDSEK NMISKLKTEC GCQFTSKLEG MFRDMSISNT
     TMDEFRQHIQ TTSASLSGVD LTVRVLTTGY WPTQSATPKC TIPPAPRHAF EVFRRFYLAK
     HSGRQLTLQH HMGGADLNAT FYGAVKKEDG SEVGVGGAQV TGSNTRKHIL QVSTFQMTIL
     MLFNNREKCT FEEIQQETDI PERELVRALQ SLACGKPTQR VLTKEPKSKE IENGHVFTVN
     DQFTSKLHRV KIQTVAAKQG ESDPERKETR QKVDDDRKHE IEAAIVRIMK SRKKMQHNVL
     VAEVTQQLRA RFLPSPVVIK KRIEGLIERE YLARTPEDRK VYTYVA
//