ID   A0A3Q3M9X5_9TELE        Unreviewed;      1412 AA.
AC   A0A3Q3M9X5;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Cytoplasmic linker associated protein 2 {ECO:0000313|Ensembl:ENSMAMP00000017819.2};
OS   Mastacembelus armatus (zig-zag eel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX   NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000017819.2, ECO:0000313|Proteomes:UP000261640};
RN   [1] {ECO:0000313|Ensembl:ENSMAMP00000017819.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC       {ECO:0000256|ARBA:ARBA00004629}. Golgi apparatus, trans-Golgi network
CC       {ECO:0000256|ARBA:ARBA00004601}.
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DR   Ensembl; ENSMAMT00000018292.2; ENSMAMP00000017819.2; ENSMAMG00000011902.2.
DR   GeneTree; ENSGT00940000155574; -.
DR   Proteomes; UP000261640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0000776; C:kinetochore; IEA:UniProtKB-KW.
DR   GO; GO:0015631; F:tubulin binding; IEA:InterPro.
DR   GO; GO:0031110; P:regulation of microtubule polymerization or depolymerization; IEA:UniProt.
DR   GO; GO:1902903; P:regulation of supramolecular fiber organization; IEA:UniProt.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 4.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR024395; CLASP_N_dom.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR034085; TOG.
DR   InterPro; IPR048491; XMAP215_CLASP_TOG.
DR   PANTHER; PTHR21567; CLASP; 1.
DR   PANTHER; PTHR21567:SF30; CLIP-ASSOCIATING PROTEIN 2; 1.
DR   Pfam; PF21040; CEP104-like_TOG; 1.
DR   Pfam; PF12348; CLASP_N; 1.
DR   Pfam; PF21041; XMAP215_CLASP_TOG; 1.
DR   SMART; SM01349; TOG; 4.
DR   SUPFAM; SSF48371; ARM repeat; 2.
DR   PROSITE; PS50077; HEAT_REPEAT; 1.
PE   4: Predicted;
KW   Centromere {ECO:0000256|ARBA:ARBA00023328};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Kinetochore {ECO:0000256|ARBA:ARBA00022838};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          8..228
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   REPEAT          169..207
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT   DOMAIN          308..528
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   DOMAIN          777..1014
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   DOMAIN          1168..1408
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   REGION          257..281
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          525..575
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          614..700
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1013..1055
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1156..1175
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1181..1212
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        525..548
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        614..669
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1412 AA;  156981 MW;  F5DDC575EA926A3E CRC64;
     MEEHDNMDYF YQQILQKDVS RRLQVGQDLI DYLNDPQRSP DVEQDKPRLD KTIDELPGWV
     NASNFKVALL GIDICGAFVD RLGERFKGYL GTVLPALVDR LGDGKDQVRE NSQALILRCM
     EQAAPPMYVW ERLFPGFKHK NFRCREGICL CLSATLTTYG AQPLGLSKIV PYLCSLTEDQ
     NPQVREASVT TLVDVYRHIG EKVRADLGKR GLPAARFHVD DNTLLSPLLP DRSFEDDDSV
     DGSRSFSAQA AFKVPKVPKK PVESSSARRP SATGGKLVSK ESAGAVDEED FIRAFTDVPT
     VQIYSTRDLE DNLNKIREVC SDDKHDWDQR AIALKKIRSL LVAGAPNYDC FYQHLRLLDG
     AFKLSAKDLR SQVVREACIT VAHLSSVLGN KFDHGAEAIV PVLFNLIPNC AKVMATSGVS
     AIRIIIRHTH VPRLIPLITS NCTSKSVAVR RRCYDFLDLL LQEWQTHSLE RHTAVLVDST
     YRHFLKLCYV EEKNHFPAEA DALYNSLEPS YQRTLQSYLK TSGSVASLPQ SDRSSSSSQE
     SLNRPLSSKW SAAPGRVTAG SKGGVTPASL QRSRSDVDVN AAAAAKYRLT KCVSVASIVF
     LQFPLYIQTG RVRTKQPLST ASSVSSQVDS RGRSRTKMVS QSQPGSRSGS PGRVLTSTAL
     STMSSGAHRV LGSASGDGRR RSRIPRSQGC SRDSSPTRLS VGFGISQSSR LSSSVSAMRV
     LNTGSDVEEA LADALKKPAR RRYENYSMYS DDDANSDASS ACSERSYSSR NGGAIPTYMR
     QTEDVAEVLN RCASANWSER KEGLLGLQAL LKNQRTLSRV ELKRLCEIFT RMFADPHSKV
     FSMFLETLVD FIQVHKDDLQ DWLFVLLTQL LKKMGADLLG SVQAKVQRAL DITRESFPND
     LQFTILMRFT VDQTQTPNLK VKVAILKYIE TLTLQMEAPD FVNSSETRLA VSRIITWTTE
     GKSSDVRKAA QSVLIALFQL NTPEFTMLLA ALPKTFQDGA TKLLQNHLKN TGNIAPMGSP
     LTRHTPRSPA SWSSPVTSPT NTSQNTPSPS AFDYDTENMN SEDIYSSLKG VTEAIQNFSV
     RSQEDMNEPV QRRDGEEVGI QAHMELLHGT DGRDSMDGVR MALDNKTSLL NTPLLSSSPR
     GARELFSDSP FKYGRRDTSL DDSEHLTDGT QTRPDRRSEL VAELLKELSN HNERIEERKA
     ALCELLKLIR ENTLQVWDEH FKTILLLLLE TMGDREHVIR TLALRVLREI LSKQPWRFKN
     YAELTIMKAL EAHKDPHKEV IRAAEETAAM LALSISPDQC IKVLCPIIQS ADYPINLAAI
     KMQTRVVERI PRESLISMVP EIVPGLIQGY DNSESSVRKA CVFCLVAVHA VIGEDLKPHL
     SQLSSSKLKL LNLYIKRAQS GSSGGEPPSE GL
//