ID A0A3Q3ME53_9TELE Unreviewed; 461 AA.
AC A0A3Q3ME53;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Paired box protein Pax-8 {ECO:0000256|ARBA:ARBA00039822};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000019294.1, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000019294.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3Q3ME53; -.
DR STRING; 205130.ENSMAMP00000019294; -.
DR Ensembl; ENSMAMT00000019794.2; ENSMAMP00000019294.1; ENSMAMG00000012962.2.
DR GeneTree; ENSGT00940000161868; -.
DR InParanoid; A0A3Q3ME53; -.
DR OrthoDB; 5393942at2759; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00131; PAX; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR043182; PAIRED_DNA-bd_dom.
DR InterPro; IPR001523; Paired_dom.
DR InterPro; IPR022130; Pax2_C.
DR InterPro; IPR043565; PAX_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR45636; PAIRED BOX PROTEIN PAX-6-RELATED-RELATED; 1.
DR PANTHER; PTHR45636:SF6; PAIRED BOX PROTEIN PAX-8; 1.
DR Pfam; PF00292; PAX; 1.
DR Pfam; PF12403; Pax2_C; 1.
DR PRINTS; PR00027; PAIREDBOX.
DR SMART; SM00351; PAX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00034; PAIRED_1; 1.
DR PROSITE; PS51057; PAIRED_2; 1.
PE 4: Predicted;
KW Paired box {ECO:0000256|ARBA:ARBA00022724};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 8..134
FT /note="Paired"
FT /evidence="ECO:0000259|PROSITE:PS51057"
FT REGION 150..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 189..203
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 461 AA; 49458 MW; 041B694F2FB3E773 CRC64;
MSNNTGRGHG GLNQLGGMFV NGRPLPEVIR QRIVDMAHQG VRPCDISRQL RVSHGCVSKI
LGRYYETGSI KPGVIGGSKP KVATPKVVEK IAEYKRQNPT MFAWEIRDRL LAEGVCDSDT
VPSVSSINRI IRTKVQQPFN LSLDGKGLSP GQTLIPSSAV TPPESPQSDS LGSTYSISGL
LGIPQPSGEG KRTHDDSDQE SCRHSVDSQG SGGVPRKQMR VDHFSTATQH LDCGFDRHHY
PSDSFSSASS SKTEQTLYPL SLINGSLDEA KTSLSTSSAI GRNLTAHQSY TMVTEPLQPL
SLCLKQEMSP DVTSTSSSPN MTTSNLAFME LQALQKPVSV SSSCSSSNHF ANAFNSFSHH
APVYGQFSSQ PIISGRDMVS STLPGYPPHI TSPAQTGYSS SAITGMVAAG ADYTGQSYSH
SPYTSYSEAW RFTNSSILGS PYYYSSASRT APPSAAAYDH L
//
