ID A0A3Q3MFJ2_9TELE Unreviewed; 2091 AA.
AC A0A3Q3MFJ2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Fras1 related extracellular matrix 1b {ECO:0000313|Ensembl:ENSMAMP00000023932.1};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000023932.1, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000023932.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the FRAS1 family.
CC {ECO:0000256|ARBA:ARBA00005529}.
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DR Ensembl; ENSMAMT00000024542.2; ENSMAMP00000023932.1; ENSMAMG00000016024.2.
DR GeneTree; ENSGT00940000165098; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007154; P:cell communication; IEA:InterPro.
DR Gene3D; 2.60.40.2030; -; 1.
DR InterPro; IPR038081; CalX-like_sf.
DR InterPro; IPR003644; Calx_beta.
DR InterPro; IPR039005; CSPG_rpt.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR045658; FRAS1-rel_N.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR PANTHER; PTHR45739:SF3; FRAS-RELATED EXTRACELLULAR MATRIX PROTEIN 1B PRECURSOR; 1.
DR PANTHER; PTHR45739; MATRIX PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF16184; Cadherin_3; 11.
DR Pfam; PF03160; Calx-beta; 1.
DR Pfam; PF19309; Frem_N; 1.
DR SMART; SM00237; Calx_beta; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF141072; CalX-like; 1.
DR PROSITE; PS51854; CSPG; 11.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..2091
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018556817"
FT REPEAT 275..369
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 394..481
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 502..596
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 763..854
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 875..969
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1011..1114
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1135..1243
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1264..1362
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1383..1475
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1496..1588
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1619..1716
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT DOMAIN 1722..1822
FT /note="Calx-beta"
FT /evidence="ECO:0000259|SMART:SM00237"
FT REGION 1840..1878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1890..1959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1843..1860
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1861..1875
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1913..1946
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2091 AA; 231227 MW; 7FCDFE6FA9EDD396 CRC64;
MAAVRAVLSL VLTAVCSAGL VVVNSGVEVG RGRSVFITEK ELKINVEPTA DCKVEVVMNE
PVTQRVGKLT PQVFDCSFLQ DEVKYTHSGS PLLDEDTVML RVYRFTSSDT QVETVVLPVR
VVDSMSGVVE LGSAPLVVSQ FYGLSNAIDS SILHIRTRVD LVCTVRLIST DTNVPAVGQL
VTEEDSTQRK GRQTAALCPG NKPCPHDTKE VRFLKTSCQD FLNSGLKYQH LSPPSPQIDY
IPIRVELREQ ATRVLLESEA VWLPVLIHGA MQNQPPQAAF MASFILEVDQ FILTPFTTAA
LDAKDHETPQ ERLVFNITVQ PAEGYVTHLD DHTKPVTSFT WLDLHDMKVA YQPPNSGQAH
RRNYEVEFQA IDGSYMTSPP ITVHISIRAA ETNAPRVSWN MGLDLLEGQS RPITWEELQI
VDNDNINAVY LVAVDGPLHG SLSVRGGKAF MFRVRDLREG VVVYHHSDSD TTRDHIVFRI
SDGRHSIRHK FPINILPKDD SPPFLINNVA VEVQEGGAVR LEEYLLLASD LDSSDDYILY
QIVSTPRAGQ LVRKTSTHET GAPVDSFLQR DLIQGLIYYQ HSGEEQFEDS FDVTLSDSHQ
PPNLSQTYTV VVHVFPVKDQ LPVEVSGSVR SLRVKETEVV YITQAHLHFT DREHPDSDLT
YVITQHCFSP LLMDAGRLFY TDSINAMKKD HMVPVLKSFT QVWTETSCLA HAVKHRKVAF
MPPVEDVGPE PLFVQFGFSV SDQHGGTVSG LLFNITVTPV DDQAPEAFTN LLRVEEGGAA
YVTEEHLLVQ DRDTHEEGLR VQVQRTARHG RLELQGQTLL QGDKFSLQDL RGLRLRYIHD
DSETSEDEVG LKVTDGLNSA DVVLLIQVLP MNDEPPQLGA GLRGELSCEE GGRVQVTVDY
LSATDRDSDD SRLTYMLARS PSRGELQKTG LTVDKFSQQD LLQGHIYYVH TGGEIGPEPV
FDTVTLIISD GEAGSTDSCC HGDAPPPPVP LHGTLPVYDL NITIIPVNNK VPTVTLGESM
LVVDEGSSAC LCAGVLAASD PDSPPDQLIF HLESPPLHGF LENTLPTPGS EKSNAGVRVE
SFRLIHLTSG FINYVQSEHK WAEPTVDQLS ISVSDGLHRS APVPFYIIIN PTNDELPSLL
LANFTVKEGG MRELTPSILD GLDLDAPPDI LTFTVVQPPA HGVLINGIYG TEMSRYKEMG
ADLLQRSLPV TSFTLQELQQ GMKIVYMHDD TETLEDTVAL RLTDGVHTVQ GTAQVTVLPV
NDEKPRLLRN AGLDVDSGDH RVISSVVLEA EDLDTPANQV YYFVNAAPRF GKLQLKSGWQ
ELTAGQNFTQ DDVEMNRLWY RHVAAAGTPG FKGHDSFRFT LSDLDNDTPA QSFFIAVHTV
HKGDIELHSK AVHLREGQRV VLNTDILLAS DSAGHPEELV FMVSVPPRHG LVHAVQRPGV
ALISFTQLDV AAHRVCYTHD NSHDTEADSF SFVVTNGDSS RSGTLHFTIE HGDRIPPTLN
HNTGLRLQAG STETITSSHI QLTDPDTATT NLTYIVTQPP RYGKLLLRAV PLRPPLRFTQ
TDVDELKLAY RHNPGSPAEI DRFYFLPTDG NNRGYLEFGQ LREEPAVFNI QVDQVDRTPP
SLTTRRSPST VVDLGGERYG LFITNKHLQG FDPDSPTEEL EFSIIRPPHF GYLENAHTGA
YIKGRFTQRD VDQRAVVFVL PADMEVTADS FQFRLTDPAG NAMLPETLEL SWSRVELSAT
CYRTCETAGT LQIQIQRHGR SIDPAYVAIQ VEEGSAKPGR DFTHSTASLV QFDPGVGVKA
WNIYLIDDGL EENHETFTVT LKNPKNAILG QRTSASVEII DPRGGRCDPD DLRVEEDKKS
PPAPPPGLPD PPMPEEDPVT DIEAELLWEN QPHPPRGDVP NRQPYLDYGE AQPQDQGGSS
YSHTHYHIRQ LPGTSAESSG STGSRVRHEE PTVGDSSSFG CYKRLSPPTK GSLWLILTCF
HSLLILSSPQ SISWSCPDGW TLYSGHCYIL GSSVATWASA KQSQPGALAQ WTWTGRRIIS
TPLLRGAWLD PFEPATAGHC VLVEHTRLWS RTSCTKKTQH KFICSFRAHG D
//
