ID A0A3Q3MG72_9TELE Unreviewed; 1164 AA.
AC A0A3Q3MG72;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Integrin, alpha 11b {ECO:0000313|Ensembl:ENSMAMP00000021836.1};
GN Name=ITGA11 {ECO:0000313|Ensembl:ENSMAMP00000021836.1};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000021836.1, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000021836.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
CC -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC {ECO:0000256|ARBA:ARBA00008054, ECO:0000256|RuleBase:RU003762}.
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DR AlphaFoldDB; A0A3Q3MG72; -.
DR Ensembl; ENSMAMT00000022390.2; ENSMAMP00000021836.1; ENSMAMG00000014552.2.
DR GeneTree; ENSGT00940000155465; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd01469; vWA_integrins_alpha_subunit; 1.
DR Gene3D; 1.20.5.930; Bicelle-embedded integrin alpha(iib) transmembrane segment; 1.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 2.
DR Gene3D; 2.60.40.1460; Integrin domains. Chain A, domain 2; 1.
DR Gene3D; 2.60.40.1510; ntegrin, alpha v. Chain A, domain 3; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR000413; Integrin_alpha.
DR InterPro; IPR013649; Integrin_alpha_Ig-like_1.
DR InterPro; IPR048285; Integrin_alpha_Ig-like_2.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR032695; Integrin_dom_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF21; INTEGRIN ALPHA-11; 1.
DR Pfam; PF01839; FG-GAP; 2.
DR Pfam; PF08441; Integrin_A_Ig_1; 1.
DR Pfam; PF20805; Integrin_A_Ig_2; 1.
DR Pfam; PF00092; VWA; 1.
DR PRINTS; PR01185; INTEGRINA.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00191; Int_alpha; 5.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR SUPFAM; SSF69179; Integrin domains; 2.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS51470; FG_GAP; 4.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW ECO:0000256|RuleBase:RU003762};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037, ECO:0000256|RuleBase:RU003762};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU003762};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU003762};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003762};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU003762}.
FT TRANSMEM 1084..1108
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT REPEAT 42..100
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT DOMAIN 182..363
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REPEAT 480..543
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 545..603
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 607..667
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REGION 1118..1148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1164 AA; 128834 MW; E583F0FA6707FC2D CRC64;
SGPVGLAVLS DSSMLEHTPG VLSLHIPVAI DKKSELCFNF DTKNFKIFFG SKEAQFGYTV
QQHEAGGRQW LLVGAPFEST GRQQTGDVYR CPLDTRNSAN CSRLNLGKLS LDNVSERKDN
MRLGMTLTSN PKDSSFVTCG PLWSHECGSS LYSTGLCSRI GRNFRLSHTI APALQRCEMF
MDIVIVLDGS NSIYPWYEVQ DFLINVLHKF YIGPGQTQVG VVQYGSTVVH EFSLGEYHTV
EEVVEAARSI SQRGGEETRT ALGINVARLE AFQRGGRPGA QKVMIVITDG ESHDSPQLVQ
AVADSERDNI TMYAIAVLGY YNRRGINPEA FLKEIKFIAT DPDEKHFFNV TDESALKDIV
DALGERIFSL EGQNGRGFGL QMAQAGFSSH LVKDGVLLGA VGAYDWNGAV LKDTKHGKVV
PPKSSYKDEF PEDLKNHGAY LGYAVGSLVS SRGSQLYVAG APRFNHTGKV IIFTLRNTGN
LTILHALLGE QIGSYFGSEL LSMDVDSDGH TDVLLVAAPM YYSQGWERGR VYIYTVTPQM
PFFLQGALEV SDRPQNSRLG SALAQIPDMN GDGFTELVVG APLEDDHQGA VYVFYGQDKT
IRRQYRQRLS AATFSSGLQY FGQSLHGVLD MNADGLVDLA VGALGAAVII WSRGVVRIHA
KLTFEPEKVN IFNKDCQRGG KDVTCMSVIV CLSLDSRTNV RAKTRTDVAL WYSLVLDERR
FPPRAVLDEL DRQQPRTVIL PVTHTLAKHF CEQETTDYGR PIAVVLETGM QDPDEGPVLD
PDWPSTLRAE LPFWNGCEQE DTCVPDLILH SHTDLMDVQQ FCSSRDQSTW SLCRQQGGSE
SSGFVVEAGR RRMVVFARLE NQGENAYGAA IHISTSSNLL FSSLIVKDQS DIQIECYAED
QLANQRFCNI SAPFMKSLSQ VLIYTILLDL PASTQVTVTL RGRLQLPALL AVSISDTIHP
FSIPTYSLTR VTGISKSQVA NPGPSCCEAT VLTTQPPCCS VCLFVSTRTS ALRVQPFGYQ
ECGSVKCHQT PDTVHSLFQV NFRSLEILVA ASIQLEASSP MFLQEDRPVR QIILELRKEE
DYSIPVWVIL GSLLGGLLLL ALLVLALWKV RARARTHTHT HTHTHTHTHP HTRTHTHTHT
HTHTHTHTHT HTHLCQQWTS PLFL
//
