ID A0A3Q3MJD1_9TELE Unreviewed; 565 AA.
AC A0A3Q3MJD1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Segment polarity protein dishevelled homolog DVL-3-like {ECO:0000313|Ensembl:ENSMAMP00000027668.2};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000027668.2, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000027668.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the DSH family. {ECO:0000256|ARBA:ARBA00008735}.
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DR AlphaFoldDB; A0A3Q3MJD1; -.
DR STRING; 205130.ENSMAMP00000027668; -.
DR Ensembl; ENSMAMT00000028382.2; ENSMAMP00000027668.2; ENSMAMG00000018559.2.
DR GeneTree; ENSGT00950000182903; -.
DR InParanoid; A0A3Q3MJD1; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd04438; DEP_dishevelled; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.240.130; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR024580; Dishevelled_C-dom.
DR InterPro; IPR008339; Dishevelled_fam.
DR InterPro; IPR003351; Dishevelled_protein_dom.
DR InterPro; IPR001158; DIX.
DR InterPro; IPR038207; DIX_dom_sf.
DR InterPro; IPR015506; Dsh/Dvl-rel.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10878; SEGMENT POLARITY PROTEIN DISHEVELLED; 1.
DR PANTHER; PTHR10878:SF6; SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-3; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF02377; Dishevelled; 1.
DR Pfam; PF00778; DIX; 1.
DR Pfam; PF12316; Dsh_C; 2.
DR Pfam; PF00595; PDZ; 1.
DR PRINTS; PR01760; DISHEVELLED.
DR SMART; SM00021; DAX; 1.
DR SMART; SM00049; DEP; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50841; DIX; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687, ECO:0000256|PROSITE-
KW ProRule:PRU00069}.
FT DOMAIN 2..83
FT /note="DIX"
FT /evidence="ECO:0000259|PROSITE:PS50841"
FT DOMAIN 168..240
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 332..406
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT REGION 103..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 446..565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..146
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..490
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 496..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..552
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 565 AA; 61801 MW; 727572C9DC2EE4C1 CRC64;
MAEGTRVIYH LDDQETPYLI RINVPAQRVT LADFKQVLNK PNVKFFFKSV DDDFGVVKEE
ISDEDARLPC VNGRVICWVV SSDTCQSDIQ SVATPISLAP PPIERTGVIG DSRPPSFQFS
QSTEQSSSSP RLVRRQRRRH RKPKTARMER SVSFSSVTDS TMSLNIITVT LNMERYNFLG
ISIVGQSNDR GDGGIYIGSI MKGGAVAADG RIEPGDMLLQ VNDINFENMS NDDAVRVLRE
IVHKPGPVTL TVAKCWDPNP RGCFTLPRSE PVRPIDPAAW VSHTAAMTGR LLPHYGTTPI
SHCSIVPSIT CSENQLNIHS DMTAVVKAMA NPESGLEVRD RMWLKITIPS AFIGSDVVDW
LHRNVEGFTD RREARKYAGN LLKAGFIRHT VNKVTFSEQC YYVFGDLYLG LMTLLDHEGA
SSRAGGSDCD PLALASGPQW PPAFPYQYPI PDPYSSPQLP AWGGGEGGSQ HSEGSRSSGS
NCSDAQKEGG GSEPTKQLES PGNSSICRPQ ISIAGLHGNK DLKDPPSPPR GQHQDLSSAP
PEISTSRQSF RLAMGNPGDF FVDVM
//
