ID   A0A3Q3MNT7_9TELE        Unreviewed;       184 AA.
AC   A0A3Q3MNT7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 1B {ECO:0000256|ARBA:ARBA00020090};
DE   AltName: Full=DARPP-32 {ECO:0000256|ARBA:ARBA00029874};
DE   AltName: Full=Dopamine- and cAMP-regulated neuronal phosphoprotein {ECO:0000256|ARBA:ARBA00030254};
GN   Name=PPP1R1B {ECO:0000313|Ensembl:ENSMAMP00000024486.1};
OS   Mastacembelus armatus (zig-zag eel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX   NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000024486.1, ECO:0000313|Proteomes:UP000261640};
RN   [1] {ECO:0000313|Ensembl:ENSMAMP00000024486.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Inhibitor of protein-phosphatase 1.
CC       {ECO:0000256|ARBA:ARBA00002900}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the protein phosphatase inhibitor 1 family.
CC       {ECO:0000256|ARBA:ARBA00007775}.
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DR   AlphaFoldDB; A0A3Q3MNT7; -.
DR   STRING; 205130.ENSMAMP00000024486; -.
DR   Ensembl; ENSMAMT00000025117.2; ENSMAMP00000024486.1; ENSMAMG00000016479.2.
DR   GeneTree; ENSGT00730000111283; -.
DR   InParanoid; A0A3Q3MNT7; -.
DR   OrthoDB; 4018581at2759; -.
DR   Proteomes; UP000261640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   InterPro; IPR008466; PPP1R1A/B/C.
DR   PANTHER; PTHR15417:SF2; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1B; 1.
DR   PANTHER; PTHR15417; PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN; 1.
DR   Pfam; PF05395; DARPP-32; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261640}.
FT   REGION          1..74
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          108..184
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..24
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        116..150
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        166..184
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   184 AA;  20694 MW;  D87A6E8828A55D62 CRC64;
     MDPLLPADTE VMEREADKDS RRKIQFSVPS SVPTQLDPGQ VEMIRRRRPT PATLFRLTDQ
     PSPEEDSGPH QWVLGENGAL RPKLVHMSTY QPPSLKAVQR MAQAHFSSLD MTSVDKEEPS
     SGEEEEHGEI KSQQKGLATD LREESKLFRD QCAPSDISAA STELSLHCRA EEEEAKDRQE
     GKQE
//